AUG 02, 2022 6:30 AM PDT

A New, Innovative Process for Clarifying and Sterile Filtering Cells for Protein Purification Workflows

SPONSORED BY: Pall Life Sciences


Centrifugation and filtration have been widely accepted as techniques required for clarifying complex cell cultures to recover extracellular proteins such as monoclonal antibodies (mAbs). However, these steps can be time consuming and costly for labs growing their cultures in 24-well plates. This scientific brief offers an alternative to the use of centrifugation/filtration/flocculation to clarify and sterilize mammalian cell cultures. It describes an assessment of a new 24-well clarification and sterile filtration plate and a 24-well sterilization-only filter plate for the recovery of proteins present in the supernatant.

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Scientists and engineers at heart, we thrive on helping customers protect people, the environment and our natural resources. We are often called "the original clean technology company" because our products provide clear environmental benefits. Pall fluid management solutions enable customers to purify and conserve water, consume less energy, make alternative energy possible and practical, advance medicine, and minimize emissions and waste. By doing so we're helping to make our world safer, greener and better every day.
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