JUN 10, 2019 12:10 PM PDT

Tart Cherry and Pain Management in Breast Cancer Patients

WRITTEN BY: Nouran Amin

In patients with non-metastatic breast cancer, treated with aromatase inhibitors, tart cherry was found to reduce the musculoskeletal effects of the drug. The findings were based on a clinical trial by researchers at Marshall University Joan C. Edwards School of Medicine and Edwards Comprehensive Cancer Center.

"The flavonoids and anthocyanins in tart cherry have anti-inflammatory properties and may be playing a role in reducing the side effects of joint pain and muscles aches, although etiology of aromatase-induced arthralgias remain unclear at this time," said principal investigator Maria Tria Tirona, M.D., professor of hematology-oncology at the Marshall University Joan C. Edwards School of Medicine and director of medical oncology at Edwards Comprehensive Cancer Center. "There was a statistically significant difference in the pain levels experienced by patients in the group that received the tart cherry concentrate compared to the placebo group."

Currently, aromatase inhibitors (AIs) therapeutics are the standard treatment option for hormone receptor-positive breast cancer in postmenopausal women. The drug can prevent reemergence of the disease by blocking the activity of aromatase, an enzyme that is responsible for converting androgens to estrogens. However, an estimated half of all patients treated with AIs will suffer from joint and muscle pain. That particular pain is known as aromatase inhibitor induced arthralgia and at times can often be so painful and debilitating that it leads to patients to stop treatmetns earlyleading to patients stopping treatments.

Learn more about aromatase inhibitors (AIs):

But, in the randomized, double-blind trial of 60 participants, the consumption of 1 ounce of tart cherry concentrate in 8 ounces of water daily for six weeks with a placebo group in women was compared with stage 1, 2 or 3 non-metastatic breast cancer.

Patients were required to document their pain intensity at the beginning of the trial, weekly and at study completion. Upon completion, 34.7% of patients reported a mean decrease in pain compared to just 1.4% in the placebo group.

Source: Joan C. Edwards School of Medicine

 

About the Author
  • Nouran earned her BS and MS in Biology at IUPUI and currently shares her love of science by teaching. She enjoys writing on various topics as well including science & medicine, global health, and conservation biology. She hopes through her writing she can make science more engaging and communicable to the general public.
You May Also Like
OCT 21, 2020
Microbiology
The First Treatment for Ebola is Approved by FDA
OCT 21, 2020
The First Treatment for Ebola is Approved by FDA
Ebola virus can pass from animals to humans, and between people. Rarely, it causes outbreaks but when it does, they can ...
OCT 23, 2020
Drug Discovery & Development
FDA Gives Full Approval to Remdesivir to Treat COVID-19
OCT 23, 2020
FDA Gives Full Approval to Remdesivir to Treat COVID-19
The US Food and Drug Administration (FDA) has approved antiviral drug Remdesivir, sold under the name ‘Velkury&rsq ...
OCT 27, 2020
Cardiology
Boron Could Prevent Myocardial Fibrosis and Assist in Recovery
OCT 27, 2020
Boron Could Prevent Myocardial Fibrosis and Assist in Recovery
When you pass by the nutrition section at the local grocery store, there is a chance you’ll come across row upon r ...
OCT 29, 2020
Drug Discovery & Development
Scientists Create Antibiotic from Komodo Dragon Blood
OCT 29, 2020
Scientists Create Antibiotic from Komodo Dragon Blood
Researchers from George Mason University in Washington DC have created a synthetic molecule from Komodo Dragon blood tha ...
NOV 26, 2020
Cannabis Sciences
Women More Likely than Men to Swap Prescription Medication for Cannabis
NOV 26, 2020
Women More Likely than Men to Swap Prescription Medication for Cannabis
The stigma around cannabis usage is fading as cannabis laws become increasingly lax. Now, researchers from DePaul Univer ...
NOV 30, 2020
Microbiology
Common Antibiotic Could be Effective Zika Treatment
NOV 30, 2020
Common Antibiotic Could be Effective Zika Treatment
Zika virus cause a devastating epidemic in 2015, and led to the birth of hundreds of children that had congenital brain ...
Loading Comments...