OCT 14, 2019 11:18 AM PDT

Aspirin May Reduce Effects of Air Pollution on Lungs

WRITTEN BY: Nouran Amin

New research findings, published in the American Journal of Respiratory and Critical Care Medicine, are the first to suggest that the nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin can reduce the adverse effects of air pollution on lung function.

"Our findings suggest that aspirin and other NSAIDs may protect the lungs from short-term spikes in air pollution," says first and corresponding author Xu Gao, PhD, a post-doctoral research scientist in the Department of Environmental Health Sciences at the Columbia Mailman School. "Of course, it is still important to minimize our exposure to air pollution, which is linked to a host of adverse health effects, from cancer to cardiovascular disease."

Learn more on how air pollution impacts the body:

The study was generated from analysis examining the relationship between test results, self-reported NSAID use, and ambient particulate matter (PM) and black carbon in the month preceding the test. The study also examined health status of participants and whether or not they smoked. Results showed that NSAID used almost halved of the effect of PM on lung function.

"While environmental policies have made considerable progress toward reducing our overall exposure to air pollution, even in places with low levels of air pollution, short-term spikes are still commonplace," says senior author Andrea Baccarelli, MD, PhD, chair of the Department of Environmental Health Sciences at the Columbia Mailman School. "For this reason, it is important to identify means to minimize those harms."

Although most of the modifying effects was observed from aspirin use as opposed to any other NSAID, researchers believe that NSAID generally mitigates inflammation in the lungs when exposed to pollutants in the air. However, the exact mechanism remains largely unknown as more research is needed.

Source: Mailman School of Public Health

About the Author
BS/MS
Nouran is a scientist, educator, and life-long learner with a passion for making science more communicable. When not busy in the lab isolating blood macrophages, she enjoys writing on various STEM topics.
You May Also Like
APR 14, 2022
Drug Discovery & Development
COVID-19 Drug Combo More Effective than Single Drugs
APR 14, 2022
COVID-19 Drug Combo More Effective than Single Drugs
COVID-19 is more effectively treated by a combination of drugs than singular drugs alone. The corresponding study was pu ...
APR 20, 2022
Health & Medicine
The Link between Mental Health and COVID Breakthrough Infection
APR 20, 2022
The Link between Mental Health and COVID Breakthrough Infection
Researchers from University of California San Francisco and the San Francisco Veterans Affairs Health Care System conduc ...
MAY 20, 2022
Drug Discovery & Development
Drug Shows Promise in treating Spinal Cord Injury
MAY 20, 2022
Drug Shows Promise in treating Spinal Cord Injury
A drug developed by AstraZeneca preserves 80% of nerve function following spinal cord compression injury. The correspond ...
JUN 07, 2022
Health & Medicine
Drug that lowers blood sugar also reduces blood vessel dysfunction caused by aging
JUN 07, 2022
Drug that lowers blood sugar also reduces blood vessel dysfunction caused by aging
Cardiovascular diseases (CVDs) are the leading cause of death globally, taking an estimated 17.9 million lives ...
JUN 11, 2022
Drug Discovery & Development
Inhaled Aerosol Vaccines More Effective than Nasal Sprays
JUN 11, 2022
Inhaled Aerosol Vaccines More Effective than Nasal Sprays
Inhaled aerosol vaccines provide more protection than nasal sprays and evoke a stronger immune response. The correspondi ...
JUN 16, 2022
Cancer
Dance/Movement Therapy Benefits Cancer Patients
JUN 16, 2022
Dance/Movement Therapy Benefits Cancer Patients
For cancer treatment, standard of care (sometimes referred to as best practice or standard therapy) defines medical trea ...
Loading Comments...