OCT 30, 2019 10:20 AM PDT

Advancing Nanocontainers for Drug Delivery

WRITTEN BY: Nouran Amin

Nanocontainers work by delivering drugs to a localized region in the body, many chemotherapeutics work in that matter. The high specificity of this drug delivery method often is advantageous in avoiding unusual and unwanted side-effects. However, there is always room for improvement--"My group wants to understand in as much detail as possible how the container molecules and the active substances arrange and what properties result from this," says chemistry professor Ann-Christin Pöppler from Julius-Maximilians-Universität (JMU) Würzburg in Bavaria, Germany.

As the loading with curcumin (yellow) increases, the dissolution rate of the containers made of polymeric micelles (blue) decreases. (Image: Ann-Christin Pöppler / Universität Würzburg)

The latest research regarding advancing drug delivery includes a chain of molecules known as polymeric micelles that assemble into spherical structures. "Little is known about the molecular origin of the properties of these structures," says Pöppler. They are already on the market as drug containers and have been used in cosmetics and cancer therapy. The micelles work when they touch fat-soluble products causing them to form a "water-loving" outer shell and a "fat-loving" core.

Learn more about micelles:

Findings were published in the scientific journal Angewandte Chemie which describe the polymeric micelles used in the study. The micelles were derived from substance classes poly(2-oxazoline)s and poly(2-oxazine)s. One of the active substances was taken from the Curcumin spice plant as it is easy to spectroscopically visualize.

Source: Science Daily

About the Author
  • Nouran earned her BS and MS in Biology at IUPUI and currently shares her love of science by teaching. She enjoys writing on various topics as well including science & medicine, global health, and conservation biology. She hopes through her writing she can make science more engaging and communicable to the general public.
You May Also Like
FEB 21, 2020
Health & Medicine
FEB 21, 2020
Frequent Cannabis Use Could Affect Driving Safety
A new study suggests that heavy marijuana users have the potential to be dangerous drivers. However, hazardous driving appears to be isolated to users who ...
FEB 25, 2020
Drug Discovery & Development
FEB 25, 2020
China Approves Trials for Favipiravir to Treat Coronavirus
As of February 25th 2020, there have been 80, 354 reported cases of COVID-19 (Wuhan coronavirus), including 2,707 deaths and 27,898 recoveries. Currently w...
FEB 26, 2020
Microbiology
FEB 26, 2020
NIAID Tests Remdesivir as a Treatment for COVID-19
A case of coronavirus has now occured in the US in someone without a known link to an infected person or travel....
MAR 02, 2020
Drug Discovery & Development
MAR 02, 2020
DIY Fecal Transplants Improve Symptoms in 82% of People
Fecal transplants (FMT), the process of putting a healthy person’s fecal matter into another person’s colon, has been approved as a procedure t...
MAR 19, 2020
Drug Discovery & Development
MAR 19, 2020
Does Sucking Zinc Lozenges Help Fight off Coronavirus?
As panic is spreading over the novel coronavirus, the time is ripe for both misinformation and disinformation to thrive. In particular, sucking zinc lozeng...
MAR 12, 2020
Drug Discovery & Development
MAR 12, 2020
Brain Stimulants Help with Focus
Drugs like Ritalin, Adderall and similar medications have been assumed by the public as fuels to help people focus. But, how exactly do they work? Now, a n...
Loading Comments...