NOV 19, 2019 09:02 PM PST

Antibiotics from the Sea?

WRITTEN BY: Nouran Amin

Many of the clinically relevant antibiotics are sourced from natural substances, produced by bacteria. But because of the growing threat of antibiotic resistance, there is a dire need of antibiotic developments—with targeted cultivation of potential antibiotics producers.

"Talented producers are primarily microorganisms with complex lifestyles, an unusual cell biology and large genomes," explains microbiologist Christian Jogler of Friedrich Schiller University, Jena. "Such organisms produce antibiotic compounds and deploy them in the fight against other bacteria for nutrients and habitats," he adds.

Researchers are now looking at the sea as a potential antibiotic source.

Specifically, they are examining the marine bacterium ‘Planctomycetes’ with 79 samples of pure cultures from the Mediterranean, the North Sea, the Baltic Sea and the Black Sea, as well as the Atlantic, the Pacific and the Arctic Ocean.

"We know that Planctomycetes live in communities with other microorganisms and compete with them for habitat and nutrients," says Jogler, explaining what makes this group of bacteria of interest to the researchers.

Uni-Jena.de: Posidonia oceanica off the coast of Corsica. On this plant many planctomycetes have been found. Image Credit: Christian Jogle

"These pure cultures together represent 31 new genera and 65 new species," adds lead author Dr. Sandra Wiegand. "The bioinformatic analysis was holistic in its approach. The results of these analyses show that the newly obtained Planctomycetes have extraordinarily complex lifestyles and have the potential to produce new antibiotics.”

Researchers used bioinformatics and microscopic methods that were used to characterize the newly obtained samples with a focus on their bacterial cell division. "They divide in a very different way from all other important pathogenic bacteria," says Jogler. "Hypothesis-driven cultivation and holistic characterization are essential for discovering something really new and opening up new therapeutic avenues.”

Source: Science Daily

About the Author
  • Nouran enjoys writing on various topics including science & medicine, global health, and conservation biology. She hopes through her writing she can make science more engaging and communicable to the general public.
You May Also Like
DEC 12, 2019
Microbiology
DEC 12, 2019
Potential New Antibiotic Discovered in Soil-Dwelling Microbe
Many of our best antibiotics have come from microbes, which have to use them to battle other microorganisms in a struggle for resources....
DEC 12, 2019
Drug Discovery & Development
DEC 12, 2019
Therapeutic Targets Inflammation Associated with Genetic Heart Disease
Often times when young athletes collapse during the game it is due to sudden cardiac death as a result of the inherited arrhythmogenic cardiomyopathy (ACM)...
DEC 12, 2019
Drug Discovery & Development
DEC 12, 2019
Novel Therapeutic For Eradicating The Flu Virus
Public Health officials have long warned about pandemic pathogens flying fast around the world. One virus already spreads across the globe annually leading...
DEC 12, 2019
Drug Discovery & Development
DEC 12, 2019
Psychedelic DMT Creates Vivid Waking Dream State in Brain
In a new study, scientists at Imperial College London investigated how powerful psychedelic dimethyltryptamine (DMT) alters the brain’s electrical ac...
DEC 12, 2019
Drug Discovery & Development
DEC 12, 2019
New Injection that Treats Peanut Allergy
Peanut allergies affect between 1 and 3% of the US population. Associated with a heightened risk of severe anaphylactic reactions, oral immunotherapy is th...
DEC 12, 2019
Microbiology
DEC 12, 2019
Hybrid Antibiotic Can Destroy Dangerous Staph Biofilms
When staph begins to grow on medical devices like implants used on wounds, artificial joints, or catheters, they can cause chronic, serious infections....
Loading Comments...