DEC 09, 2020 10:51 PM PST

Rapid-Release Capsule for IBS

WRITTEN BY: Nouran Amin

Researchers have developed a rapid-release capsule to treat symptoms of irritable bowel syndrome with constipation (IBS-C).

"We know bile acids are capable of helping with motility, but what has been attempted in the past is giving a bolus -- a boatload of bile acid all at once. This manifests in increased bowel movements, but also pain," said Giovanni Traverso, MD, PhD, of the Brigham's Division of Gastroenterology, Hepatology and Endoscopy and the Department of Mechanical Engineering at MIT. "Could we take this endogenous, natural product and deliver it in a way that overcomes this risk of contractions?"

Findings were published in the journal Clinical and Translational Gastroenterology.

"While further studies are necessary to demonstrate the therapeutic potential of these systems in humans, our findings suggest that controlled delivery of bile acids to the colon may represent a novel approach to treating gastrointestinal diseases such as constipation," said co-author Joshua Korzenik, MD, of the Brigham's Gastroenterology and Hepatology Division.

Learn more about irritable bowel syndrome:

 

 

Source: Science Daily

About the Author
  • Nouran earned her BS and MS in Biology at IUPUI and currently shares her love of science by teaching. She enjoys writing on various topics as well including science & medicine, global health, and conservation biology. She hopes through her writing she can make science more engaging and communicable to the general public.
You May Also Like
NOV 02, 2020
Immunology
New Cancer Drug Reboots Stalled Immunotherapies
NOV 02, 2020
New Cancer Drug Reboots Stalled Immunotherapies
In contrast to traditional chemotherapies, immunotherapies reprogram the patient’s own immune system to fight tumo ...
NOV 01, 2020
Cannabis Sciences
Can Cannabis Treat ALS?
NOV 01, 2020
Can Cannabis Treat ALS?
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative illness that damages motor neurons and leads to progressive m ...
NOV 06, 2020
Drug Discovery & Development
New Vaccine Shows Promise for Herpes
NOV 06, 2020
New Vaccine Shows Promise for Herpes
The World Health Organization estimates that over 500 million people have Herpes Simplex Virus Type 2 (HSV-2), a sexuall ...
NOV 09, 2020
Microbiology
Fighting COVID-19 with Help From Llamas
NOV 09, 2020
Fighting COVID-19 with Help From Llamas
Camelids, which include llamas, alpacas and camels have immune systems that generate two kinds of antibodies when confro ...
DEC 25, 2020
Drug Discovery & Development
Class of Antibiotics May Target Resistant Bacteria
DEC 25, 2020
Class of Antibiotics May Target Resistant Bacteria
Researchers found a new class of antibiotics for combatting antimicrobial resistance (AMR). Learn more about antibiotic ...
JAN 09, 2021
Drug Discovery & Development
Anticoagulant Drugs Prevent Cancer Spreading to Brain
JAN 09, 2021
Anticoagulant Drugs Prevent Cancer Spreading to Brain
Researchers from the Heidelberg University in Germany have found that anticoagulant drugs that inhibit thrombin (an enzy ...
Loading Comments...