JUL 12, 2021 7:01 AM PDT

Testosterone Supplements Reduce Heart Attack and Stroke Risk

WRITTEN BY: Annie Lennon

Taking testosterone supplements significantly reduces risk of heart attack and stroke among men with low levels of the hormone. The findings were presented at the European Association of Urology Congress

Previous research has found a link between testosterone deficiency in men and an increased risk of cardiovascular conditions. Over 100 studies have also shown that testosterone therapy, or supplementing with testosterone, has a positive effect on cardiovascular conditions and risk factors. 

For the study, researchers recruited over 800 men from both Germany and Qatar with low testosterone and symptoms including low mood, decreased appetite, and depression. Assessments of each participant's family history, blood pressure, cholesterol levels, diabetes, and weight showed that they were at significant risk of having a heart attack or stroke. 

All in all, 412 of the men chose to take long-term testosterone supplements, whereas the other half chose not to. This allowed the researchers to assess the effects of testosterone supplementation on cardiovascular risk factors over a 10-year timeframe. Nevertheless, all men were encouraged to improve their cardiovascular health via lifestyle changes, including adjusted diets, alcohol consumption, smoking, and exercise.

 In the end, the researchers noted that of the 412 men on testosterone therapy, 16 died during the study period, although none suffered from a heart attack or stroke. Meanwhile, of the 393 men not on testosterone supplements, 74 died, 70 had a heart attack, and 59 had a stroke. Even when factors such as age were considered, this discrepancy remained. 

The researchers noted that men on testosterone therapy also saw improvements in other aspects of health. These participants also lost more weight, had more lean muscle mass, and more regulated cholesterol levels. Their liver function also improved, their diabetes was better under control, and their blood pressure fell. 

The researchers said that their results were surprising, given that all of the men in the study, including those on testosterone therapy, were expected to suffer a heart attack or stroke within five to ten years. 

"For those at high risk of heart attack and stroke, who are deficient in testosterone, it's likely that bringing the hormone back to normal levels helps them to maximize the benefits of other steps necessary to improve their overall health." says Omar Aboumarzouk, from the Hamad Medical Corporation in Qatar, "This includes increasing exercise levels, eating healthier food, giving up smoking and reducing alcohol consumption."

"We believe that physicians treating patients with low testosterone, who are at high risk of heart attack or stroke, should consider testosterone therapy as one aspect of their treatment," he added. 

 

Sources: European Association of Urology CongressEur CardiolEurekAlert

About the Author
Other
Annie Lennon is a writer whose work also appears in Medical News Today, Psych Central, Psychology Today, and other outlets. When she's not writing, she is COO of Xeurix, an HR startup that assesses jobfit from gamified workplace simulations.
You May Also Like
DEC 02, 2022
Genetics & Genomics
Tips on Establishing a Reliable Cell Free DNA Workflow
Tips on Establishing a Reliable Cell Free DNA Workflow
Ever since its first discovery in 1948, circulating cell-free DNA (cfDNA) has captured the attention and imagination of ...
NOV 29, 2022
Cell & Molecular Biology
How a Master Regulator May be Working to Protect Cancer
How a Master Regulator May be Working to Protect Cancer
Scientists have now discovered yet another way that MYC proteins can promote cancer. MYC has been called a master regula ...
DEC 03, 2022
Neuroscience
Promising Epilepsy Treatment Suppresses Neuroinflammation
Promising Epilepsy Treatment Suppresses Neuroinflammation
A team of City University of Hong Kong (CityU) neuroscientists recently identified and developed a new drug candidate fo ...
DEC 12, 2022
Clinical & Molecular DX
NIH Awards Millions of Dollars to Develop a Drug to Target the Emerging Chikungunya Virus
NIH Awards Millions of Dollars to Develop a Drug to Target the Emerging Chikungunya Virus
Chikungunya virus is a mosquito-borne illness, meaning it is spread by the bite of an infected mosquito. The virus can c ...
JAN 24, 2023
Immunology
Remove Dead Cells for Increased Accuracy
Remove Dead Cells for Increased Accuracy
Even viability dyes need controls. Don’t have time to “kill” a control for this? Don’t worry- we ...
JAN 11, 2023
Plants & Animals
Canadian sea sponge contains COVID-blocking compounds
Canadian sea sponge contains COVID-blocking compounds
Since the start of the COVID-19 pandemic, researchers have studied the virus with a near singular purpose: finding ways ...
Loading Comments...