Explore the transformative role of three-dimensional (3D) cell models, like organoids and spheroids, in advancing medicine. These models provide a more physiologically relevant environment than traditional two-dimensional (2D) cultures, offering crucial insights into disease understanding and targeted treatment development. However, the complexity of 3D models requires innovative solutions to maintain their integrity and viability. High-throughput processing is essential for efficiently generating and analyzing large volumes of data, with life science instrument technology companies developing solutions to meet these demands.
Advancements include live-cell imaging platforms like Incucyte® Live-Cell Analysis, enabling continuous monitoring of 3D cultures without disturbing cellular biology, and providing real-time insights into gene expression and cell behavior. Automated systems such as Incucyte and CellCelector Flex facilitate high-throughput workflows, maintaining the viability and integrity of delicate structures like induced pluripotent stem cells (iPSCs) and organoids.
The eBook highlights the importance of standardized workflows for high-throughput cell manipulation and analysis, featuring application notes on culturing, maintaining, and characterizing iPSCs, as well as label-free, real-time live cell assays for 3D organoids. These technologies enhance the reproducibility, efficiency, and physiological relevance of 3D cell models, accelerating breakthroughs in precision medicine and translational research.
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The Sartorius Group is a leading international partner of biopharmaceutical research and the industry. With innovative laboratory instruments and consumables, the Group's Lab Products & Services Division concentrates on serving the needs of laboratories performing research and quality control at pharma and biopharma companies and those of academic research institutes. The Bioprocess Solutions Division with its broad product portfolio focusing on single-use solutions helps customers to manufacture biotech medications and vaccines safely and efficiently.
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