Head of Molecular and Cellular Pharmacology, Bioprojet BiotechBiography
Dr. Thierry Calmels is currently heading the Molecular and Cellular Pharmacology department at Bioprojet Biotech, with a focus on Neuroscience and Inflammation therapeutic areas. Dr. Calmels' main research focus is on G-protein Coupled Receptors (GPCRs) with the aim of setting up screening and secondary assays, as well as to dissect their signaling mechanisms for proposed drug targets. Dr. Calmels has specialized in implementing calcium mobilization assays for GPCRs in drug discovery as well as for human iPSC-derived cardiomyocytes in cardiac safety. Dr. Calmels got his Ph.D. in Applied Genetics at the University of Toulouse (France), after which he moved to Pittsburgh (USA) for a Post-Doc in Pharmacology with Dr. J. Lazo. After spending 3 years in Pittsburgh, Dr. Calmels joined the Molecular Oncology department with Pr. D. Stéhelin at the Pasteur Institute in Lille, France, followed by 5 years at GlaxoSmithKline (GSK) within the Cardiology Unit before joining Bioprojet in 2001.