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Monday, April 19th, 11:15AM EDT

ASH Anticoagulation Guidelines in Patients with COVID-19: A moving target

Sponsored by: Diagnostica Stago, Inc.
C.E. Credits: P.A.C.E. CE Florida CE
Speaker
  • Professor of Anesthesiology and Critical Care & Professor of Surgery (Cardiothoracic) - Duke University School of Medicine
    Biography

      Jerrold Levy is Professor of Anesthesiology, Critical Care, Surgery (Cardiothoracic) at Duke University Medical Center in Durham, NC. He obtained his medical degree from the University of Miami, where he was an intern in internal medicine, and undertook his residency in the Department of Anesthesiology of the Massachusetts General Hospital and Harvard Medical School in Boston, where he was also Chief Resident, and completed fellowships in both Respiratory ICU and Cardiac Anesthesiology. He previously was Professor, Deputy Chair for Research, and Chief of Cardiothoracic Anesthesiology at Emory University. His clinical and research interests include anticoagulation and its reversal, therapeutic strategies to prevent and treat coagulopathy and acute inflammatory responses in critically ill patients, clinical applications of recombinant and purified protein concentrates, and pharmacologic approaches to treat shock. His clinical practice involves managing critically ill patients with cardiopulmonary dysfunction, shock, and extracorporeal circulation in the ICU. His current appointments include Chair of the Subcommittee on Perioperative and Critical Care Thrombosis and Hemostasis for the International Society of Thrombosis and Hemostasis, Executive Editor of Anesthesiology, and consultant to the FDA‘s Biologic Products Advisory Committee. He is an elected Fellow of the American Heart Association and Society of Critical Care Medicine, and the author of over 500 publications, including original research articles, reviews, chapters, and editorials with over 78,000 citations and an h-index of 88. He is also fluent in French and conversational in Spanish and Japanese.



      Wikipedia page: https://en.wikipedia.org/wiki/Jerrold_Levy Faculty



      Website: https://scholars.duke.edu/person/jerrold.levy



      Google Scholar page: https://scholar.google.com/citations?user=qnH5V28AAAAJ&hl=en



      Twitter: @JerroldLevy



      Publications: https://pubmed.ncbi.nlm.nih.gov/?term=levy+jh&sort=date


    Abstract
    ASH Anticoagulation Guidelines in Patients with COVID-19: A moving target
     

    The American Society of Hematology (ASH) published in February 2021 “Anticoagulation Guidelines in Patients with COVID-19”. (https://ashpublications.org/bloodadvances/article/5/3/872/475154/American-Society-of-Hematology-2021-guidelines-on). Despite the extensive work and using evidence-based methodology their findings were as follows:

    The panel agreed on 2 recommendations. The panel issued conditional recommendations in favor of prophylactic-intensity anticoagulation over intermediate-intensity or therapeutic-intensity anticoagulation for patients with COVID-19–related critical illness or acute illness who do not have confirmed or suspected VTE.

    These recommendations were based on very low certainty in the evidence, underscoring the need for high-quality, randomized controlled trials comparing different intensities of anticoagulation. They will be updated using a living recommendation approach as new evidence becomes available.

    However, ongoing interim analysis of three randomized controlled trials, REMAP-CAP, ACTIV-4, and ATTACC (ClinicalTrials.gov: NCT 02735707, 04505774, and 04372589, respectively) will be used to update this recommendation.

     
    Learning Objectives
    • Summarize the recent American Society of Hematology (ASH) guideline
    • Update the ongoing data based changes in recommendations based on ACTIV studies
    • Discuss relevance to coagulation laboratory based testing practices and clinical relevance
    • Offer some clinical perspectives from managing hemostatic dysfunction in COVID-19 and using laboratory testing for optimal management
     
     
    LabRoots is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E. ® Program. By attending this webinar, you can earn 1 Continuing Education credit once you have viewed the webinar in its entirety.  CE credits are available for this webinar up to 2 years from the date of the live broadcast

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