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APR 14, 2021 12:00 PM PDT

New Challenges for SARS-CoV-2 Diagnostics: Viral Load Testing and Variant Strain Genotyping

Sponsored by: LGC Seracare
C.E. Credits: P.A.C.E. CE Florida CE
Speakers
  • Chief Scientific Officer, LGC SeraCare
    Biography

      Russell Garlick, PhD, is the Chief Scientific Officer at LGC SeraCare Life Sciences. Since 2012 he has been focusing on expanding the company's technologies, R&D organization, and product development pipeline. Throughout his career he has worked on the development, regulatory approval, and launch of a variety of technologies and assays, including an HIV/AIDS patient management program, molecular genomics technologies, and HIV drug discovery systems. Prior to joining LGC Clinical Diagnostics, Dr. Garlick was co-founder of Life Sciences Group and served as CEO and CTO of Protein Forest, Inc. He has also held executive R&D positions at PerkinElmer Life Sciences and DuPont NEN Life Sciences.

    • Professor and Vice Chair, Pathology; Medical Director, Medical College of Wisconsin
      Biography

        Nathan A. Ledeboer, PhD, is a Professor and Vice Chair of Pathology and Medical Director of Microbiology, Molecular Diagnostics, reference services, and Laboratory Client Services at Froedtert Hospital and Wisconsin Diagnostic Laboratories in Milwaukee, WI.  His research endeavors, particularly in the area developing diagnostic tools for infectious diseases, have led to numerous publications in peer-reviewed journals and more than 100 funded research projects.  Dr. Ledeboer is also a senior editor for the Journal of Clinical Microbiology.


      Abstract

      Even as COVID-19 vaccines are being deployed around the world, the clinical laboratory will continue to play a major role this year helping to control the pandemic by diagnosing new infections and improving disease management. This webinar will discuss two critically important issues clinical labs are facing today: 1) SARS-CoV-2 viral load testing and the clinical correlates and 2) early detection of new strains that are more infectious or more pathogenic using genotyping assays. Dr. Nate Ledeboer, PhD Professor and Vice Chair, Pathology; Medical Director, Medical College of Wisconsin will present his views on these topics and will share data from his laboratory. Dr. Russell Garlick, PhD, Chief Scientific officer LGC Clinical Diagnostics, will present the technologies used to advance viral load standardization and strain genotyping by qPCR and NGS assays. The webinar will include a 15 minute Q&A session.

      Learning Objectives:

      1. Discuss the benefits and barriers to reporting Ct values in SARS-CoV-2 PCR tests

      2. Explore the process of developing quantitative standards to support SARS-CoV-2 viral load testing

      3. To review and understand SARS-CoV-2 variants and their impact on laboratory testing

      4. To review and understand the use of SARS-CoV-2 recombinant viral reference materials for assay development and QC of genotyping assays


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