NOV 06, 2019 10:30 AM PST

Drug discovery and pharmacology of antivirals targeting drug-resistant influenza viruses

Presented at: Influenza 2019
C.E. Credits: Florida CE P.A.C.E. CE
Speaker
  • Assistant Professor, Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona
    BIOGRAPHY

Abstract

The efficacy of current influenza antiviral drugs is compromised by emerging drug resistance. To address this unmet medical need, we have made progress in developing novel influenza antivirals by targeting the drug-resistant mutants of M2 and the viral polymerase. In this presentation, I will introduce our work in designing inhibitors targeting the viral M2-S31N mutant proton channel and the viral polymerase PA-PB1 interactions. The designed M2-S31N inhibitors and the PA-PB1 inhibitors have been shown to inhibit drug resistant influenza viruses with potent antiviral efficacy and a high selectivity index. 


Show Resources
You May Also Like
MAY 11, 2021 10:00 AM PDT
C.E. CREDITS
MAY 11, 2021 10:00 AM PDT
Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
SEP 14, 2021 7:00 AM PDT
C.E. CREDITS
SEP 14, 2021 7:00 AM PDT
Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...
JUN 09, 2021 7:00 AM PDT
C.E. CREDITS
JUN 09, 2021 7:00 AM PDT
Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
OCT 20, 2021 10:00 AM PDT
C.E. CREDITS
OCT 20, 2021 10:00 AM PDT
Date: October 20, 2021 Time:10:00am (PDT), 1:00pm (EDT) As the prevalence of Diabetes continues to rise in many areas across the globe, healthcare providers continue to look for methods that...
OCT 12, 2021 9:00 AM PDT
C.E. CREDITS
OCT 12, 2021 9:00 AM PDT
Date: October 12, 2021 Time: 9:00am (PDT), 12:00pm (EDT) SCIEX’s next-generation Biologics Explorer software is an innovative platform for the comprehensive and deep characterization o...
JUL 15, 2021 8:00 AM PDT
C.E. CREDITS
JUL 15, 2021 8:00 AM PDT
Date: July 15, 2021 Time: 8:00am (PDT), 11:00am (EDT) High dimensional full spectrum flow cytometry grants unprecedented access to previously unattainable parameters in cellular biology. Flu...
NOV 06, 2019 10:30 AM PST

Drug discovery and pharmacology of antivirals targeting drug-resistant influenza viruses

Presented at: Influenza 2019
C.E. Credits: Florida CE P.A.C.E. CE

Specialty

Molecular Biology

Microbiology

Clinical Diagnostics

Immunology

Biotechnology

Infectious Disease

Cancer Research

Laboratory Testing

Biochemistry

Gene Expression

Genetics

Dna

Animal Research

Biomarkers

Genomics

Geography

Asia54%

North America39%

Europe7%

Registration Source

Website Visitors86%

Email Promotions11%

Social Media Promotions4%

Job Title

Student36%

Research Scientist16%

Medical Laboratory Technician12%

Medical Doctor/Specialist8%

Educator/Faculty8%

Microbiologist8%

Clinical Laboratory Scientist4%

Veterinarian4%

Lab Management4%

Organization

Academic Institution50%

Medical School7%

Government7%

Research Institute7%

Clinical Laboratory7%

General Laboratory4%

Hospital4%

Pharmaceutical Company4%

Medical Center4%

Veterinary School4%

Manufacturer - Other4%


Show Resources
Loading Comments...
Show Resources