OCT 25, 2017 06:00 AM PDT

WEBINAR #3: Enabling neurological disease research via DNA fragment analysis on the new SeqStudio genetic analyzer

SPONSORED BY: Thermo Fisher Scientific
C.E. CREDITS: P.A.C.E. CE | Florida CE
Speakers
  • Senior Vice President, Research and Development, Asuragen
    Biography
      Dr. Gary Latham is Senior Vice President of R&D for Asuragen, a molecular diagnostics company focused on genetics and oncology. Gary joined Asuragen when it was founded in 2006, and currently oversees the company's research, assay development, partnered R&D, and bioinformatic teams. He guided the development of AmplideX® PCR technology for fragile X syndrome and other DNA repeat disorders, and DNA- and RNA-based QuantideX® NGS products for oncology applications. Gary is an inventor on 12 issued US patents, has received >$13M in research grants from the NIH and the Cancer Prevention and Research Institute of Texas (CPRIT), and has authored >40 peer-reviewed publications.

    Abstract:

    DATE: October 25, 2017
    TIME: 06:00am PDT, 09:00am EDT

    This is the third topic in the webinar series on ‘Sanger Sequencing & Fragment Analysis made easy’.

    Repetitive DNA sequences comprise half of the human genome and include at least 1.6 million short tandem repeats with dark functions and unknown disease implications. Recent genome-wide studies have illuminated thousands of associations of such repeat elements with changes in gene expression. In addition, over 30 Mendelian disorders are known to be caused by triplet repeat expansions. Thus there is a rapidly growing appreciation that repetitive “dark” DNA is discoverable, discernible and diagnostic.

    In this webinar, we will discuss:

    • How reliable, long-read AmplideX® PCR technology can be combined with the SeqStudio Genetic Analyzer to operationalize the routine detection of established and emerging repeat DNA markers in an easy-to-use assay system
    • Data showing sensitive and accurate analyses of GC- and AT-rich repeat expansions and length polymorphisms associated with Fragile X Syndrome, ALS/FTD, Myotonic Dystrophy, Huntington’s Disease, and Alzheimer Disease
    • The implications of high-resolution repeat DNA genotyping for scientific and clinical research of neurodevelopmental, neurodegenerative, and neuromuscular disorders

    Other topics in the webinar series:


    Show Resources
    You May Also Like
    MAY 22, 2018 08:00 AM PDT
    C.E. CREDITS
    MAY 22, 2018 08:00 AM PDT
    DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
    MAY 03, 2018 11:00 AM PDT
    MAY 03, 2018 11:00 AM PDT
    DATE: May 3, 2018TIME: 11:00AM PDT, 2:00PM EDTWhile stress is one of the leading causes of neuropsychiatric disorders, the molecular underpinnings of how stress induces alterations in b...
    MAY 24, 2018 09:30 AM PDT
    C.E. CREDITS
    MAY 24, 2018 09:30 AM PDT
    DATE: May 24, 2018 TIME: 9:30PM PDT The current gold standard in in vitro pre-clinical cancer treatment screening remain cell lines,...
    APR 27, 2018 10:00 AM PDT
    C.E. CREDITS
    APR 27, 2018 10:00 AM PDT
    DATE: April 27, 2018TIME: 10:00am PST, 1:00pm ESTGlioblastoma (GBM) and Medulloblastoma (MB) are the most common adult and paediatric brain tumours, both of which can have devastating c...
    AUG 15, 2018 08:00 AM PDT
    C.E. CREDITS
    AUG 15, 2018 08:00 AM PDT
    DATE: August 15, 2018TIME: 08:00AM PDT, 11:00AM EDTThe failure of current chemotherapeutic strategies in the fight against cancer can be largely attributed to the occurrence of drug res...
    JUN 29, 2018 09:00 AM PDT
    C.E. CREDITS
    JUN 29, 2018 09:00 AM PDT
    DATE: June 29, 2018TIME: 09:00AM PDT, 12:00PM EDT There is significant epidemiological evidence to suggest that the consumption of a high-broccoli diet is associated with a r...
    Loading Comments...