AUG 29, 2019 9:00 AM PDT

Enabling Next-Generation Targeted siRNA Therapies with ExpiCHO

Speaker

Abstract
DATE:  August 29, 2019
TIME:   9:00am PT / 12:00pm ET
 
Monoclonal antibodies (mAbs) are a cornerstone of modern biomedical research and biotherapeutics. Therefore, reproducibly obtaining high yield and high purity mAbs while minimizing time and cost is critically important. In pursuit of this goal, we utilized the Gibco ExpiCHO Expression System to produce multiple mAbs. By optimizing several parameters, we obtained high yields from 30 mL shaker cultures at concentrations approaching 1 mg/mL in under 2 weeks. These results demonstrate the value of the ExpiCHO system as a game changing technology that brings high quantities of pure mAb within the reach of more scientists, enabling much more rapid and streamlined development of targeted therapies
 
Learning Objectives:
  • Understand the need for high-yield and high-purity monoclonal antibodies for development of biotherapeutics.
  • Understand the value of the Gibco ExpiCHO Protein Expression System in production of monoclonal antibodies
 
 
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AUG 29, 2019 9:00 AM PDT

Enabling Next-Generation Targeted siRNA Therapies with ExpiCHO



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