SEP 13, 2017 1:30 PM PDT

The escalating challenges of antimicrobial resistance and the efforts to conquer these threats

Speaker
  • Consultant Medical Microbiologist
    Biography
      Glenn Tillotson has 30+ years pharmaceutical experience in early pre-clinical and clinical research, commercialization, medical affairs, scientific communications including publication planning strategic drug development, life cycle management and global launch programs. Dr Tillotson has been instrumental in the development and launch of ciprofloxacin, moxifloxacin, gemifloxacin, fidaxomicin and most recently solithromycin. Glenn has held several key committee positions at the American College of Chest Physicians, he is on the Scientific Steering Committee for the GTCBio the Annual Summit on Anti-infective Partnering. Currently Dr Tillotson has published >150 peer-reviewed manuscripts, presented >270 scientific posters and is on several journal Editorial Advisory Boards including the Lancet Infectious Disease, eBioMedicine Expert Reviews in Anti-Infective Therapy and F1000.

    Abstract

    The global threat of antimicrobial resistance has been recognized by the World Health Organization, the United Nations and many other expert bodies. The burden of resistant pathogens is immense and only likely to escalate with predictions of millions of deaths annually and massive economic impact. Since antibiotics were available clinically bacteria have become resistant to these drugs with multi-drug resistant mutants now causing many different types of infection. Bacteria have multiple methods of becoming resistant involving target site alteration, access to the cell or modification of the removal of various molecules. Some antibiotics can be affected by all three mechanisms , such as B-lactams, while others succumb to a single change to lose their effectiveness.
    Despite major advances in new antibiotics in the 1980-1990's there have been no new classes approved since 2005, daptomycin, thus there is an impetus to identify potential new classes of agents which are safe and effective. Presently there are several novel approaches being studied which may provide some hope for new therapies. These include siderophore modifications of a standard B-lactam, agents which alter the cell membrane, quorum sensing blocking, novel targets which involve protein synthesis and other sites. This presentation will provide a brief refresher on antimicrobial resistance and then focus on a selection of new agents and platforms of research. 


    Show Resources
    You May Also Like
    MAY 11, 2021 10:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    C.E. CREDITS
    MAY 11, 2021 10:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
    DEC 02, 2020 8:00 AM PST
    C.E. CREDITS
    DEC 02, 2020 8:00 AM PST
    DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
    JUN 09, 2021 7:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    C.E. CREDITS
    JUN 09, 2021 7:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
    MAR 16, 2021 10:00 AM PDT
    C.E. CREDITS
    MAR 16, 2021 10:00 AM PDT
    Date: March 16, 2021 Time: 10:00am (PST) Scientific progress and breakthroughs today are often too expensive for most institutions to acquire. Each year, the National Institutes of Health (N...
    DEC 15, 2020 10:00 AM PST
    C.E. CREDITS
    DEC 15, 2020 10:00 AM PST
    DATE: December 15, 2020 TIME: 10:00am PST Scientists from Thermo Fisher Scientific will walk us through the world of microorganisms. They will discuss their most recent research on viruses,...
    DEC 16, 2020 8:00 AM PST
    C.E. CREDITS
    DEC 16, 2020 8:00 AM PST
    Date: December 16, 2020 Time: 8:00am (PST), 11:00am (EST) Molecular imaging of living specimens offers a means to draw upon the growing body of high-throughput molecular data to better under...
    SEP 13, 2017 1:30 PM PDT

    The escalating challenges of antimicrobial resistance and the efforts to conquer these threats


    Specialty

    Health

    Clinical Diagnostics

    Clinical Research

    Earth Science

    University

    Antibiotic Resistance Laboratory Network

    Microbiology

    Diagnostics

    Medicine

    Biomarkers

    Research

    Molecular Microbiology

    Clinical Microbiology

    Infectious Disease

    Disease

    Geography

    North America50%

    Asia25%

    Registration Source

    Website Visitors100%

    Job Title

    Executive33%

    Facility/Department Manager33%

    Medical Laboratory Technician33%

    Organization

    Diagnostic Company25%

    Manufacturer - Other25%

    Industrial Company25%


    Show Resources
    Loading Comments...
    Show Resources
    Attendees
    • See more