SEP 02, 2015 10:30 AM PDT

Growing together: Lessons learned from the characterization of the pediatric microbiome

Presented At Microbiology
  • Assistant Professor, Department of Pathology & Immunology, Baylor College of Medicine - Director, Bioinformatics and Microbial Ecology, Texas Children's Microbiome Center
      Dr. Hollister is a microbial ecologist and bioinformaticist. She is interested in quantifying and characterizing microbial communities from a wide variety of environments, including the human body. Utilizing high throughput, next-generation DNA and RNA sequence approaches, her research seeks to improve our understanding of microbial communities, their distribution across time and space, the ways in which they function, and their influence at broader scales. Dr. Hollister currently serves as the Director of Microbial Ecology and Bioinformatics for the Texas Children's Microbiome Center.


    Advances in sequencing technology and increasing recognition of the importance of our microbial world have led to unprecedented discoveries in recent years with respect to the human microbiome. We have begun to appreciate the degree to which the human microbiome is dynamic, can be highly personalized, and may be shaped by a variety of factors, including life stage. We also recognize that human-associated microbial communities have the potential to play important roles with respect to development, immunity, and health outcomes later in life. Given the potential importance of early-life exposures, establishing a baseline understanding of the pediatric microbiome is essential. Here we will address the state of the science regarding microbiome development in infancy and childhood and discuss recent findings related to the pediatric microbiome.

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