NOV 10, 2021 6:00 AM PST

High-throughput, high resolution purity and heterogeneity characterization of biologics using breakthrough multi-capillary technology

Sponsored by: SCIEX
C.E. Credits: P.A.C.E. CE Florida CE
Speaker

Event Date & Time
Date:  November 10, 2021
Time: 6:00am (PST),  9:00am (EST)
Abstract
Over the last 20 years, automated capillary electrophoresis (CE) has become an industry-preferred technique for quantitative purity and heterogeneity characterization of a variety of biotherapeutics, including monoclonal antibodies, antibody derivatives, peptides, oligonucleotides, vaccines and cell and gene therapy modalities. Innovations such as the development of a replaceable sodium dodecyl sulfate capillary gel electrophoresis (SDS-CGE) separation matrix, capillary isoelectric focusing (cIEF) workflows and high-resolution glycan CE separations have emerged as key workflows. These workflows enable highly reproducible and portable multi-attribute analysis of therapeutic quality. Over time, however, new challenges around sample throughput and workflow complexity have appeared, requiring processing of a growing number of molecules in clinical pipelines while delivering critical results more efficiently.
 
In this webinar, we take a detailed look at a new system developed by SCIEX to help address these challenges. The BioPhase 8800 system is a parallel separation CE platform that uses a multi-capillary approach to accelerate analytical throughput, which has the potential to drastically minimize product development time. This system incorporates novel technical features, including a precision-manufactured, liquid-cooled multi-capillary cartridge along with integrated UV/LIF detection, 96-well plate compatibility and on-board sample storage. Additionally, the system provides simplicity through the incorporation of intuitive method development software and touchscreen instrument control, placing system monitoring at the user’s fingertips. The BioPhase 8800 system represents an evolution in CE technology, providing innovative, intuitive workflows while maintaining industry-leading assay accuracy and precision to help you accelerate your biologic drug development.
 
Learning Objectives
  • Achieve parallel processing of eight samples to dramatically accelerate analysis and shorten new therapy development; experiment design speed can increase from 1 month to as quick as 1 week.
  • Streamline analysis by implementing consistent, comparable data throughout the pipeline, from bioprocessing to R&D to QA/QC.
  • Discover innovative data analysis to accelerate characterization from start to finish with easy-to-use drag and drop methods and sequences through the intuitive software interface on the panel touch screen.
 
 
Webinars will be available for unlimited on-demand viewing after live event.
 
LabRoots is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E. ® Program. By attending this webinar, you can earn 1 Continuing Education credit once you have viewed the webinar in its entirety.

You May Also Like
Loading Comments...
  • See More