MENU
APR 08, 2015 7:00 AM PDT

Introduction to the new USP <787>: "Subvisible Particulate Matter in Therapeutic Protein Injections"

Speaker
  • Life Science Application Manager, Beckman Coulter, Particle Counting and Characterization
    BIOGRAPHY

Abstract
This educational session will focus on some of the new demands in counting particles in liquids, with a focus on the challenges of preparing and sampling protein-based materials. USP has recently posted a new test for protein-based materials, known as USP <787>, and indicated that a companion informational chapter, USP <1787>, will be crafted to further describe methods and options for evaluating protein-based materials. This presentation will delineate the differences between the more well-known USP 788 and the new USP 789, focusing on critical sample preparation and handling to provide good data on particulate concentration in protein solutions. Two types of instruments that could be employed for this method are discussed and compared, one based on light obscuration and a second on the Coulter principle.

Learning Objectives:
  • Learn about the new demands in counting particles in liquids, with a focus on the challenges of preparing and sampling protein-based materials
  • Learn about the new test USP has recently posted for protein-based materials, known as USP <787>
  • This presentation will delineate the differences between the more well-known USP 788 and the new USP 789, focusing on critical sample preparation and handling to provide good data on particulate concentration in protein solutions
  • Learn about and compare two types of instruments that could be employed for this method, one based on light obscuration and a second on the Coulter principle

Show Resources
You May Also Like
MAY 11, 2021 10:00 AM PDT
C.E. CREDITS
MAY 11, 2021 10:00 AM PDT
Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
OCT 12, 2021 9:00 AM PDT
C.E. CREDITS
OCT 12, 2021 9:00 AM PDT
Date: October 12, 2021 Time: 9:00am (PDT), 12:00pm (EDT) SCIEX’s next-generation Biologics Explorer software is an innovative platform for the comprehensive and deep characterization o...
AUG 24, 2021 11:00 AM PDT
C.E. CREDITS
AUG 24, 2021 11:00 AM PDT
Date: August 24, 2021 Time: 11:00am (PDT), 1:00pm (EDT) Electron-based dissociation mechanisms have shown great promise for advanced characterization of biomolecules. However, routine adopti...
OCT 21, 2021 9:00 AM PDT
C.E. CREDITS
OCT 21, 2021 9:00 AM PDT
Date: October 21, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Industry guidelines for host cell protein impurity analysis emphasize the importance of process-specific and product-specific assessm...
OCT 27, 2021 6:00 AM PDT
C.E. CREDITS
OCT 27, 2021 6:00 AM PDT
Date: October 27, 2021 Time: 6:00 AM PDT, 9:00 AM EDT Etanercept is a recombinant Fc fusion protein therapeutic that has a complex distribution of post-translation modifications (PTM), such...
JUL 15, 2021 8:00 AM PDT
C.E. CREDITS
JUL 15, 2021 8:00 AM PDT
Date: July 15, 2021 Time: 8:00am (PDT), 11:00am (EDT) High dimensional full spectrum flow cytometry grants unprecedented access to previously unattainable parameters in cellular biology. Flu...
Loading Comments...
Show Resources