Webinars

MAR 14, 2018 9:00 AM PDT

IPSC-Derived Human Neurons: Introduction and Application

Presented at: Neuroscience 2018

Sponsored by: BrainXell

Speaker

Michael Hendrickson
Project Manager, BrainXell, Inc.
Biography
Mr. Hendrickson has worked for over a dozen years in the biotech industry, half of which in CNS drug development. He has a background in a range of neuroscience techniques, including rodent and human neuronal culture, as well as high-end microscopy. Currently, he provides technical support and customer interface for neuron and glia products from BrainXell.

Abstract

Biomedical research depends on the use of model systems to explore basic biology, probe disease mechanisms, and conduct drug discovery and development. However, results from such systems are often not recapitulated in man. This observation has led us to adopt the principle that a biomedical researcher should select a model system with the greatest physiological relevance to human physiology (or pathophysiology) that is technical and economically feasible for a given project. For early stage neuroscience and CNS drug discovery studies, human neurons derived from induced pluripotent stem cells (iPSCs) can meet this need. They can replace animal cells and immortalized human cell lines, which have limited predictive power to drive research in the right direction. This presentation will provide an overview of the technology used to create iPSC-derived neurons and describe some of the characteristics of these neurons. We will also discuss examples of how these neurons can be used in research applications, with a particular emphasis on drug discovery.

Show Resources

You May Also Like

DEC 02, 2020 8:00 AM PST

C.E. CREDITS

DEC 02, 2020 8:00 AM PST

Optimize your bioprocess - From shaker to bioreactor

DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...

OCT 08, 2020 7:00 AM PDT

C.E. CREDITS

OCT 08, 2020 7:00 AM PDT

Protect your cells with proper pipetting - How liquid handling...

DATE: October 8, 2020 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop thinking about ho...

NOV 18, 2020 8:00 AM PST

C.E. CREDITS

NOV 18, 2020 8:00 AM PST

Whole-organ mapping using AI and light sheet microscopy

DATE: November 18, 2020 TIME: 08:00am PDT We develop and implement technologies to solve some of the major bottlenecks in biomedical research. In particular, we establish new imaging approac...

DEC 16, 2020 8:00 AM PST

C.E. CREDITS

DEC 16, 2020 8:00 AM PST

Adding Dimensions to Multiplex Molecular Imaging

Date: December 16, 2020 Time: 8:00am (PST), 11:00am (EST) Molecular imaging of living specimens offers a means to draw upon the growing body of high-throughput molecular data to better under...

NOV 16, 2020 8:00 AM PST

C.E. CREDITS

NOV 16, 2020 8:00 AM PST

Targeted single-cell RNA sequencing enables genome-scale CRISPR...

Date: November 16, 2020 Time: 8:00am (PST), 11:00am (EST) CRISPR screening has become the prime discovery tool in modern biomedical research and drug discovery. At the same time, most screen...

Speaker: Wieland Keilholz, Ph.D. , Pawel Zajac, Ph.D. , Dr. Tilmann Buerckstuemmer

Sponsored By: Illumina

NOV 10, 2020 7:00 AM PST

C.E. CREDITS

NOV 10, 2020 7:00 AM PST

Move Forward with Automation

DATE: November 10, 2020 TIME: 7:00am PDT, 10:00am EDT Automation can provide tremendous benefits such as increased pipetting precision and accuracy, productivity, and throughput. Numerous wo...