OCT 22, 2020 12:05 PM PDT

Molecular Testing of NSCLC Biopsies: Making mountains out of molehills

C.E. Credits: P.A.C.E. CE Florida CE
Speaker
  • Medical Director, Molecular Oncology Diagnostics Laboratory - U.S. Department of Veterans Affairs
    Biography



      Dr. Kletecka a board certified and fellowship trained Molecular Pathologist. She performed her residency training in anatomic and clinical pathology at Case Western Reserve University Hospitals of Cleveland and fellowship subspecialty training in Molecular Genetic Pathology and Surgical Pathology at TriCore Reference Laboratories and the University of New Mexico Hospital. She currently serves as the Medical Director of the VISN22 Molecular Diagnostics Laboratory in Los Angeles where she and her team implemented molecular oncology testing by next generation sequencing for the VA system.


    Abstract

    Molecular testing of NCSLC biopsies is extremely important in the care and management of these patients.  However, NCSLC biopsies are typically very small and require multiple types of analysis for complete workup including H&E for diagnosis, IHC for classification, and FISH, IHC and NGS for biomarker testing.  This talk will focus on overcoming some of the challenges laboratories face when working with such a limited amount of tissue and how NGS can help.

    Learning Objectives:

    1. Review clinical guidelines for molecular testing of testing of non-small cell lung cancer specimens

    2. Become familiar with recommendations for biopsy tissue stewardship 

    3. How NGS can be used for molecular testing of NSCLC biopsies


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