OCT 27, 2015 08:00 AM PDT

Multidimensional High-Throughput Imaging with the New ImageXpress Micro Confocal System

  • Applications Scientist, Cellular Imaging, Molecular Devices, LLC
      Jayne Hesley is an Applications Scientist for Cellular Imaging at Molecular Devices, LLC. She has more than 6 years' experience developing cell-based applications using ImageXpress high content imaging systems and MetaXpress analysis software. Most recently her focus has been on utilizing stem-cell derived hepatocytes, cardiomyocytes and neurons for toxicity studies of cell viability, apoptosis, morphological changes, mitochondrial damage and autophagy. These studies include live-cell timelapse experiments as well as screening assays in 384 or 1536 well microplates. Prior to working in the imaging field, Jayne developed colorimetric and fluorescence assays, including TR-FRET and fluorescence polarization, for high-throughput screening on multi-mode readers. She has a B.S. in Animal Science and M.S. in Biology.
    • Senior Product Manager, Cellular Imaging at Molecular Devices, LLC.
        Grischa Chandy is the Senior Product Manager for Cellular Imaging at Molecular Devices. Grischa's scientific background is in cell biology, physiology and biophysics. He has used and developed imaging techniques and technologies throughout his career starting with his doctoral work at U.C. Irvine, his postdoc at U.C. Berkeley as well as Research Scientist position at Stanford University. Grischa has been with Molecular Devices for over 10 years, driving launches of the ImageXpress® Micro XL and ImageXpress Micro XLS systems, MetaXpress® Software version 3 onward, and most recently, the launch of the ImageXpress Micro Confocal system.

      Date: October 27th, 2015
      TIME: 8am PDT, 11am EDT, 3pm GMT, 11pm Beijing

      In recent years there have been great advances in automated microscopy and imaging for generating more predictive, physiologically relevant measurements for drug discovery and environmental toxicity applications. There is an increasing interest in using three-dimensional (3D) models, including cancer spheroids and tissue structures, to further enhance assay predictivity and relevance. Next-generation high-content, high-throughput tools for microscopy offer innovative and automated techniques for evaluating this complex biology.

      During this webinar, you will learn how the latest advances in our confocal high-content imaging technologies will help you tackle:
      - Drug screening of 3D cancer spheroids
      - Screening surface binding antibodies in no-wash homogenous assays with high background
      - Achieving confocal screening results at the speed of a widefield screening system

      In addition to its widefield capabilities, the new ImageXpress® Micro Confocal Imaging system’s revolutionary optical design gives you crisp confocal images whenever your assays require it. You will be able to use complex cell models, such as spheroids or cells grown in a thick matrix, with resulting data that will be more quantitative and statistically relevant than typical widefield experiments. This exciting new technology confirms Molecular Devices’ commitment to helping you maximize the impact of your research.

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