JUN 20, 2019 10:30 AM PDT
Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar

Outlier Kinases as Targets for Precision Therapy

C.E. CREDITS: P.A.C.E. CE | Florida CE
Speakers
  • Research Assistant Professor of Urology, Northwestern University, Feinberg School of Medicine
    Biography
      The overall theme of my research is to identify, characterize and target the genes that help in the progression of aggressive prostate cancers. During my postdoctoral fellowship, I developed novel approaches to identify outlier kinases in breast and pancreatic cancer and studied the role of these kinases in oncogenic progression. I continued to apply this novel matrix to identify novel biomarkers to distinguish indolent from aggressive prostate cancer and to interrogate therapeutic targets in advanced prostate cancer. Apart from identifying biomarkers and therapeutic targets, I also have an expertise in delineating oncogenic signaling and resistance mechanisms and carry out translational research. My goal is to delineate the molecular and biological differences between the prostate cancers in African-American and Caucasian men, to help progress the field towards personalized medicine.

    Abstract:

    In this presentation, Dr. Kothari will provide an overview of the Precision Medicine Initiative from NIH and how NGS technologies have helped the researchers to look deep inside the human transcriptome. Focusing on kinases, Dr. Kothari will discuss the sample centric versus gene centric approaches to analyze the transcriptome data to identify new drug targets. He will finally share his thoughts on how integrative omics approaches can help researchers find better drug targets and robust biomarkers of disease progression, that will help in achieving the goals of precision medicine initiative. 

    Learning Objectives: 

    1. To understand the merit of sample centric transcriptome analysis to identify new drug targets using NGS.
    2. To understand the merit of gene centric transcriptome analysis to identify new drug targets using nGS.
     


    Show Resources
    You May Also Like
    FEB 26, 2019 09:00 AM PST
    C.E. CREDITS
    FEB 26, 2019 09:00 AM PST
    DATE:  February 26, 2019TIME:   9:00am PST, 12:00pm EST In an era of increasingly high-throughput, large-scale biology, with companies, government and non-prof...
    MAY 16, 2019 04:00 PM CEST
    C.E. CREDITS
    MAY 16, 2019 04:00 PM CEST
    DATE: May 16, 2019TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST The emergence of NGS is revolutionizing the microbiological sciences and transforming medicine. Deep sequencing has...
    JUN 05, 2019 05:00 PM CEST
    C.E. CREDITS
    JUN 05, 2019 05:00 PM CEST
    DATE: June 5, 2019TIME: 8:00am PDT, 11:00am EDT, 5:00pm CEST Eukaryotic cell cultures respond to the most subtle influence. Apart from the risk of contamination, minimal chan...
    FEB 27, 2019 08:00 AM PST
    C.E. CREDITS
    FEB 27, 2019 08:00 AM PST
    DATE:  February 27, 2019TIME:  8:00am PST Pluripotent stem cells (PSCs) can form any tissue or cell in the body, and are the ideal starting material to manufacture...
    MAR 26, 2019 02:00 PM PDT
    C.E. CREDITS
    MAR 26, 2019 02:00 PM PDT
    DATE:  March 26, 2019TIME:  2:00pm PDT, 5:00pm EDT  Prostate cancer is the second most common form of cancer in males, affecting one in eight men by the time t...
    JUN 19, 2019 10:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    JUN 19, 2019 10:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    DATE: June 19, 2019TIME: 10:00am PDT, 1:00pm EDT As we develop new methods to create more biologically relevant models for research in understanding disease etiology and in...
    Loading Comments...
    Show Resources
    Event Countdown
    • 0 Days
    • 0 Hours
    • 0 Minutes
    • 0 Seconds