JUN 20, 2019

Precision Medicine 2019



 

Our 4th Annual Precision Medicine Virtual Event is now available On-Demand! The Precision Medicine planning committee carefully planned and selected speakers that best embodied the overall challenges, opportunities, and issues in the current landscape around precision medicine. The event will remain open 6 months from the date of the live event.  The webinars will be available for unlimited on-demand viewing.


Topics for this years event included:

  • History and Future of the Next Generation DNA Sequencing Revolution
    • Short Reads Versus Long Reads Technologies
  • Drug Development in the Era of Precision Medicine
    • Regulatory Landscape and Challenges
  • The Precision Medicine Initiative - NIH
  • Systems Pharmacology in Designing Precision Therapeutics
    • Single Cell Sequencing 
       

Continuing Education
LabRoots is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E. ® Program. By attending this event, you can earn 1 Continuing Education credit per presentation for a maximum of 14 credits.

Use #LRprecisionmed to follow the conversation!


Speakers

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Agenda
  • JUN 20, 2019 06:00 AM PDT
    Connecting Genetic and Transcriptional Variation in Acute Myeloid Leukemia at Single-Cell Resolution
    Speaker: Stephen Williams, PhD
  • JUN 20, 2019 06:00 AM PDT
    Precise DNA Sequencing: A Necessity for Precision Medicine
    Speaker: Jonas Korlach, PhD
  • JUN 20, 2019 06:00 AM PDT
    See Further: Expanded Carrier Screening Tools That Take You From Sample to Insight
    Sponsored By: QIAGEN
    Raed Samara, PhD
    Senior Global Product Manager, QIAGEN
    Rupert Yip, PhD
    Director, GPM Genetic Disease Informatics, QIAGEN
  • JUN 20, 2019 07:30 AM PDT
    Keynote Presentation: The Impact of Patient-to-Patient Variability on Combination Cancer Therapy and Precision Oncology
    Speaker: Adam Palmer, PhD
  • JUN 20, 2019 09:00 AM PDT
    Keynote Presentation: Transforming Drug Discovery with Precision Medicine
    Speaker: Khyati Shah, PhD
  • JUN 20, 2019 09:00 AM PDT
    Precision Medicine & Health in Action: Practicing an N-of-1 Approach in the Clinic
    Speaker: Florence Comite, MD
  • JUN 20, 2019 10:30 AM PDT
    Beyond the Score: Tools for Pan-Biomarker Analysis and TMB Estimation Enabling Deeper Understanding of Somatic Alterations that Contribute to Cancer Initiation, Progression and Recurrence
    Sponsored By: QIAGEN
    Beate Litzenburger, PhD
    Product Owner of QIAGEN Clinical Insight (QCI™) Intepre...
    Raed Samara, PhD
    Senior Global Product Manager, QIAGEN
  • JUN 20, 2019 10:30 AM PDT
    Outlier Kinases as Targets for Precision Therapy
    Speaker: Vishal Kothari, PhD
  • JUN 20, 2019 10:30 AM PDT
    The Massively Parallel Sequencing (MPS) Revolution
    Speaker: David Smith, PhD
  • JUN 20, 2019 12:00 PM PDT
    Antiplatelet Agents for Secondary Stroke Prevention - Can We Be More Precise?
    Speaker: Karen Albright, DO, PhD, MPH
  • JUN 20, 2019 12:00 PM PDT
    NGS Target Enrichment Solutions to Drive Discovery in Precision Medicine Research
    Sponsored By: Twist Bioscience
    Duane Hassane, PhD
    Assistant Professor of Computational Biomedicine in Med...
    Guannan Wang, PhD
    Senior Research Investigator, University of Pennsylvani...
  • JUN 20, 2019 12:00 PM PDT
    Tissue and cfDNA Rare Alleles: How Low Can We Go?
    Speaker: Seth Crosby, MD
  • JUN 20, 2019 01:30 PM PDT
    Introducing the therascreen FGFR RGQ RT-PCR Kit and Day-One Readiness at Insight Molecular Labs
    Sponsored By: QIAGEN
    David Hout, PhD
    Chief Operating Officer, Insight Genetics
    Benjamin Chaffey, PhD
    Global Product Manager, Oncology & Precision Diagnostic...
  • JUN 20, 2019 01:30 PM PDT
    Rapid Variant Modeling in a Hospital Setting
    Speaker: Matthew Bainbridge, PhD
  • JUN 20, 2019 01:30 PM PDT
    Single Cell CNV End-to-End Workflow to Dissect Tumor Heterogeneity
    Speaker: Lee Gibbs, PhD
  • History and Future of the Next Generation DNA Sequencing Revolution
  • JUN 20, 2019 06:00 AM PDT
    Connecting Genetic and Transcriptional Variation in Acute Myeloid Leukemia at Single-Cell Resolution
    Speaker: Stephen Williams, PhD
  • JUN 20, 2019 06:00 AM PDT
    Precise DNA Sequencing: A Necessity for Precision Medicine
    Speaker: Jonas Korlach, PhD
  • JUN 20, 2019 06:00 AM PDT
    See Further: Expanded Carrier Screening Tools That Take You From Sample to Insight
    Sponsored By: QIAGEN
    Raed Samara, PhD
    Senior Global Product Manager, QIAGEN
    Rupert Yip, PhD
    Director, GPM Genetic Disease Informatics, QIAGEN
  • JUN 20, 2019 10:30 AM PDT
    The Massively Parallel Sequencing (MPS) Revolution
    Speaker: David Smith, PhD
  • JUN 20, 2019 12:00 PM PDT
    NGS Target Enrichment Solutions to Drive Discovery in Precision Medicine Research
    Sponsored By: Twist Bioscience
    Duane Hassane, PhD
    Assistant Professor of Computational Biomedicine in Med...
    Guannan Wang, PhD
    Senior Research Investigator, University of Pennsylvani...
  • JUN 20, 2019 12:00 PM PDT
    Tissue and cfDNA Rare Alleles: How Low Can We Go?
    Speaker: Seth Crosby, MD
  • JUN 20, 2019 01:30 PM PDT
    Introducing the therascreen FGFR RGQ RT-PCR Kit and Day-One Readiness at Insight Molecular Labs
    Sponsored By: QIAGEN
    David Hout, PhD
    Chief Operating Officer, Insight Genetics
    Benjamin Chaffey, PhD
    Global Product Manager, Oncology & Precision Diagnostic...
  • Systems Pharmacology in Designing Precision Therapeutics
  • JUN 20, 2019 07:30 AM PDT
    Keynote Presentation: The Impact of Patient-to-Patient Variability on Combination Cancer Therapy and Precision Oncology
    Speaker: Adam Palmer, PhD
  • JUN 20, 2019 10:30 AM PDT
    Beyond the Score: Tools for Pan-Biomarker Analysis and TMB Estimation Enabling Deeper Understanding of Somatic Alterations that Contribute to Cancer Initiation, Progression and Recurrence
    Sponsored By: QIAGEN
    Beate Litzenburger, PhD
    Product Owner of QIAGEN Clinical Insight (QCI™) Intepre...
    Raed Samara, PhD
    Senior Global Product Manager, QIAGEN
  • JUN 20, 2019 10:30 AM PDT
    Outlier Kinases as Targets for Precision Therapy
    Speaker: Vishal Kothari, PhD
  • JUN 20, 2019 01:30 PM PDT
    Single Cell CNV End-to-End Workflow to Dissect Tumor Heterogeneity
    Speaker: Lee Gibbs, PhD
  • Drug Development in the Era of Precision Medicine
  • JUN 20, 2019 09:00 AM PDT
    Keynote Presentation: Transforming Drug Discovery with Precision Medicine
    Speaker: Khyati Shah, PhD
  • The Precision Medicine Initiative - NIH
  • JUN 20, 2019 09:00 AM PDT
    Precision Medicine & Health in Action: Practicing an N-of-1 Approach in the Clinic
    Speaker: Florence Comite, MD
  • JUN 20, 2019 12:00 PM PDT
    Antiplatelet Agents for Secondary Stroke Prevention - Can We Be More Precise?
    Speaker: Karen Albright, DO, PhD, MPH
  • JUN 20, 2019 01:30 PM PDT
    Rapid Variant Modeling in a Hospital Setting
    Speaker: Matthew Bainbridge, PhD
Posters

POSTER SUBMISSION GUIDELINES

Virtual poster sessions offer the opportunity to present data to a global audience via a PDF poster and video summary, and discuss results with interested colleagues through email. Posters should be submitted as a PowerPoint file. Presentations should incorporate illustrative materials such as tables, graphs, photographs, and large-print text. This content is not peer-reviewed. Submission is free.


SUBMIT YOUR ABSTRACT

Enter the following information to this Submission Form:

  • Poster Title
  • Your Name
  • Your Institution
  • Your Email
  • Abstract describing the poster


All submitted abstracts will be reviewed and decisions regarding acceptance will be made as abstracts are received. You will be notified within one week of receipt about acceptance. Further details and registration materials will be provided at that time. You do not have to be present in order to have a poster displayed. Only those abstracts approved by LabRoots may display posters at this event.

If accepted, you will also have the opportunity to record a 3-5 minute summary video for each poster. LabRoots will work with each individual to create these videos. Video links and email contact information will be included on each poster displayed.

Questions? Email Posters@LabRoots.com

LabRoots Policy

Speakers

  • Adam Palmer, PhD
    Systems Biologist, Laboratory of Systems Pharmacology, Harvard Medical School
    Biography
      Adam Palmer is a systems biologist working on the analysis and design of combination cancer therapies. Adam applies experiments, theory, and analysis of data from clinical trials of cancer therapies, with a particular interest in the origins and therapeutic consequences of cell-to-cell and patient-to-patient heterogeneity in cancers. Adam is presently a postdoctoral fellow with Peter Sorger in the Laboratory of Systems Pharmacology at Harvard Medical School. Previously, Adam completed his Ph.D in Systems Biology at Harvard University with Roy Kishony, researching the relationships between mechanisms of drug action and the evolution of antibiotic resistance.
    • Khyati Shah, PhD
      Post Doctoral Research Scholar at University of California, San Francisco
      Biography
        Khyati Shah received her Ph.D. in Molecular Pharmacology from the University of the Pacific, Stockton, California. Her graduate research was completed in the lab of Jesika Faridi, Ph.D. Her work focused on the investigation of the mechanism of Akt induced tamoxifen resistance in breast cancer. Currently, Khyati is the research fellow in Bandyopadhyay Lab since 2015. Her project involves investigation of the mechanism of resistance to targeted and immuno-therapy using systems biology approach. She has three-first author publications in the reputed peer-reviewed journals and 7 oral and 15 poster talks on the use of systemic genomics and proteomic approach to design rational combination therapy and to increase the durability of therapeutic response.
      • Karen Albright, DO, PhD, MPH
        Associate Professor of Neurology, SUNY Upstate Medical University
      • Matthew Bainbridge, PhD
        Associate Director of Clinical Genomics Research, Rady Children's Institute for Genomic Medicine
        Biography
          Matthew is the Associate Director of Clinical Genomics Research, Rady Children's Institute for Genomic Medicine, where he leads a lab that focuses on increasing the diagnostic rate by incorporating novel analysis methods of WGS data and close integration of in vivo model systems with the clinic. He first trained in next generation sequencing in 2005 at the BC Genome Sciences center where he wrote the first analysis packages for NGS ChIP-seq and RNAseq data. Subsequently, Matthew worked under Dr. Richard Gibbs at the Human Genome Sequencing center in Houston, Texas where he helped launch the first clinical exome sequencing tests.
        • Benjamin Chaffey, PhD
          Global Product Manager, Oncology & Precision Diagnostics, QIAGEN
          Biography
            Ben is a member of the Oncology Diagnostics Global Product Management team at QIAGEN, with responsibility for commercialisation of innovative new Companion Diagnostic tests around the world, including the therascreen FGFR RGQ RT-PCR Kit recently approved by the FDA in the USA. A molecular biologist and immunologist by qualification, he has over a decade of experience in the IVD industry covering a range of roles including assay development, manufacturing and product management. He is based in Manchester, UK, the QIAGEN global centre of excellence for companion diagnostic development, where the FGFR RGQ RT-PCR Kit was originally developed.
          • Florence Comite, MD
            CEO & Founder, Comite Center for Precision Medicine
            Biography
              Dr. Florence Comite is an internationally recognized leader and innovator in the field of Precision Medicine, with experience in leveraging N-of-1 data to detect, predict, and reverse disorders of aging for optimal health and vitality. Dr. Comite's startup QUANTIOME™ scales her unique approach to personalized, actionable Precision Medicine as a digital application. In 2005, Dr. Comite established the Center for Precision Medicine in New York City, where she integrates and interprets genomic, metabolomic, and phenotypic data; and provides tailored interventions to executives, physicians, celebrities, and self-quantifiers around the globe. Dr. Comite is a graduate of Yale School of Medicine where she was a faculty member for 25 years and founder of Women's Health at Yale. She is an endocrinologist with multidisciplinary training in Internal Medicine, Pediatrics, Gynecology, and Andrology at the National Institute of Child Health and Human Development, National Institutes of Health. A clinical investigator, Dr. Comite has published original research in numerous clinical journals and contributes regularly to editorial publications. Her most recent abstracts, presented at the Endocrine Society in 2017 and 2018 on the imprecision of lab data, are in preparation for publication. In 2013, she authored the Amazon bestseller for men, Keep It Up: The Power of Precision Medicine to Conquer Low T and Revitalize Your Life!
            • Seth Crosby, MD
              Director Scientific Collaboration , Department of Genetics, Washington University School of Medicine
              Biography
                Seth Crosby is the Director of Science Collaboration in the Department of Genetics at Washington University. Crosby works with groups within and outside the University to leverage technology to achieve research and clinical goals. He has been at Washington University for 16 years. During that time, he directed the Department of Genetics Microarray Core, which is now part of GTAC and then GTAC, itself, during its first two years. Prior to that he was the Director of Translational Research at the Genome Center (now the McDonnell Genome Institute). Prior to his tenure at Washington University, Dr. Crosby worked in the field of genomics and drug discovery at Abbott Laboratories, Pfizer and Pharmacia.
              • Lee Gibbs, PhD
                Postdoctoral Research Associate, Department of Translational Genomics, Keck School of Medicine, University of Southern California
                Biography
                  Dr. Lee D. Gibbs is a postdoctoral research associate and USC Provost's scholar in the Department of Translational Genomics at Keck School of Medicine of University of Southern California under the mentorship of Dr. John D. Carpten. He works with a multi-disciplinary team to evaluate genomic alterations that are inherited and acquired during tumor development and to understand the clinical significance of these events. His research focuses on using novel genomic sequencing technologies to reveal the unexplored landscape of tumor heterogeneity spatially and at a single cell resolution. In addition, his research focuses on the discovery and validation of biomarkers and therapeutic targets in rare and aggressive cancers that affect minorities and medically underserved populations. Dr. Gibbs's goal is to evaluate the functional significance of these genomic events and their potential to determine prognosis, diagnosis, and therapeutic response.
                • Duane Hassane, PhD
                  Assistant Professor of Computational Biomedicine in Medicine, Weill Cornell Medical College
                  Biography
                    Dr. Duane Hassane is Director of Leukemia Genomics of the Englander Institute of Precision Medicine at Weill Cornell Medicine (WCM) and an Assistant Professor of Computational Biomedicine in Medicine. Prior to joining WCM, Dr. Hassane completed his postdoctoral training in AML stem cell research at the University of Rochester School of Medicine where he focused on precision drug discovery using genomic approaches. His research group focuses on AML detection, therapy, clonal hematopoiesis, and minimal residual disease (MRD). His research led to the development of several NGS based tests in oncology including the ExACT-2 platform for augmented pan-cancer exome analysis, a New York State approved myeloid malignancies test, and the forthcoming PreCISE-1 test for clonal hematopoiesis.
                  • David Hout, PhD
                    Chief Operating Officer, Insight Genetics
                    Biography
                      Dr. Hout is the Chief Operating Officer at the Nashville, TN based diagnostic company, Insight Genetics, Inc. Dr. Hout received his Ph.D. in molecular virology and has more than 15 years of assay development and design experience throughout his tenure. Dr. Hout has published and presented extensively on the development, validation, and performance of both qPCR and Next Generation sequencing clinical assays in peer reviewed journals and at national meetings. He is also board certified as a licensed Laboratory Supervisor and has extensive experience with both CLIA and CAP compliance.
                    • Jonas Korlach, PhD
                      Chief Scientific Officer, Pacific Biosciences
                      Biography
                        Jonas Korlach was appointed Chief Scientific Officer of Pacific Biosciences in July 2012. He was previously a Scientific Fellow, supporting commercial development of the PacBio RS II system and performing research aimed at developing new applications for SMRT technologies. He co-invented the SMRT technology with Stephen Turner, Ph.D., Pacific Biosciences Founder and Chief Technology Officer, when the two were graduate students at Cornell University. Dr. Korlach joined Pacific Biosciences as the company's eighth employee in 2004. Previously, he was a Postdoctoral Researcher at Cornell University. Dr. Korlach is the recipient of multiple grants, an inventor on 70 issued U.S. patents and 61 international patents, and an author of over 70 scientific studies on the principles and applications of SMRT technology, including publications in Nature, Science, and PNAS. In 2013, Dr. Korlach was honored by the Obama White House as an Immigrant Innovator "Champion of Change." He received both his Ph.D. and his M.S. degrees in Biochemistry, Molecular and Cell Biology from Cornell, and received M.S. and B.A. degrees in Biological Sciences from Humboldt University in Berlin, Germany.
                      • Vishal Kothari, PhD
                        Research Assistant Professor of Urology, Northwestern University, Feinberg School of Medicine
                        Biography
                          The overall theme of my research is to identify, characterize and target the genes that help in the progression of aggressive prostate cancers. During my postdoctoral fellowship, I developed novel approaches to identify outlier kinases in breast and pancreatic cancer and studied the role of these kinases in oncogenic progression. I continued to apply this novel matrix to identify novel biomarkers to distinguish indolent from aggressive prostate cancer and to interrogate therapeutic targets in advanced prostate cancer. Apart from identifying biomarkers and therapeutic targets, I also have an expertise in delineating oncogenic signaling and resistance mechanisms and carry out translational research. My goal is to delineate the molecular and biological differences between the prostate cancers in African-American and Caucasian men, to help progress the field towards personalized medicine.
                        • Beate Litzenburger, PhD
                          Product Owner of QIAGEN Clinical Insight (QCI™) Intepret
                          Biography
                            Dr. Beate Litzenburger is the product owner of QIAGEN Clinical Insight (QCI™) Intepret. Prior to joining the QIAGEN team, Dr. Litzenburger led clinical decision support for several next generation sequencing research protocols at MD Anderson Cancer Center. In this role, Dr. Litzenburger was responsible for providing alteration interpretation, drug, and clinical trial options to clinicians. Dr. Litzenburger received her Ph.D. in molecular genetics from the University of Aachen in Germany and was a National Cancer Institute-supported post-doctoral fellow in the Department of Clinical Cancer Prevention at MD Anderson Cancer Center.
                          • Raed Samara, PhD
                            Senior Global Product Manager, QIAGEN
                            Biography
                              Raed Samara, PhD is a Global Product Manager for NGS technologies at QIAGEN, with a focus on pre-analytics and targeted enrichment. Prior to joining QIAGEN, he was a postdoctoral fellow at the National Cancer Institute conducting research in the field of cancer immunology with emphasis on identifying strategies to boost the efficacy of cancer vaccines. He received his Ph.D. degree from Georgetown University in tumor biology.
                            • David Smith, PhD
                              Professor and Consultant, Department of Laboratory Medicine and Pathology, Mayo Clinic
                              Biography
                                David I Smith received his Ph.D. in Biochemistry from the University of Wisconsin in Madison in 1978 studying antibiotic resistance in bacteria. After doing post-doctoral work first at the Albert Einstein College of Medicine and then at the University of California, Irvine, he got his first faculty position at Wayne State University in 1985. In 1996 he joined the Mayo Clinic as a full Professor in the Department of Laboratory Medicine and Pathology. His laboratory studies the common fragile sites which are regions of profound genomic instability that are found in all individuals. His laboratory also studies the various ways that human papillomavirus is involved in the generation of different cancers. Dr. Smith is also the Chairman of the Technology Assessment Group for the Mayo Clinic Center for Individualized Medicine. The role of this group is to evaluate new technologies that could have a profound impact on basic research and its' clinical translation. The most exciting technology that has the greatest potential to change both research and clinical practice is next generation sequencing and Dr. Smith and his group have been using this technology to answer scientific questions. The advances in next generation sequencing over the past 10 years have been nothing short of incredible and it is now possible to generate terrabases of DNA sequence in a single run of a next generation sequencer. This technology can be utilized in a number of ways from characterizing just a few genes all the way to whole genome sequencing.
                              • Guannan Wang, PhD
                                Senior Research Investigator, University of Pennsylvania
                                Biography
                                  Dr. Guannan Wang is a trained molecular biologist and cancer genomics expert at University of Pennsylvania. She determines to dedicate her knowledge and skills to better understanding diseases and discovering new therapies, ultimately making positive impacts on patient care. Being a hardcore animal lover, Dr. Wang is now spearheading the effort to bring precision medicine into veterinary oncology, through personalized diagnosis and precision clinical trials in client-owned animals, ultimately improving care and treatment for our companion animals.
                                • Stephen Williams, PhD
                                  Senior Scientist, Computational Biology, 10X Genomics
                                  Biography
                                    Dr. Williams is a Senior Computational Biologist at 10x Genomics in Pleasanton, CA. He received his PhD from Virginia Commonwealth University in 2010 and continued in academia until 2015 pursuing postdoctoral fellowships at both the Salk Institute for Biological Studies and University of Virginia. Dr. Williams has published many manuscripts in high impact journals which range in focus from genetics and genomics to cardiovascular disease and cancer. In 2016 Dr. Williams joined 10x Genomics in the Applications group. His current research focuses on developing and applying novel single-cell and spatial technologies to unravel complex biological systems.
                                  • Rupert Yip, PhD
                                    Director, GPM Genetic Disease Informatics, QIAGEN
                                    Biography
                                      An industry veteran, Rupert has helped early NGS companies including Life Technologies and Illumina successfully commercialize their sequencing platforms while making bioinformatics more accessible to the late adopters. As the leader of QIAGEN Bioinformatics' Hereditary Disease Portfolio, he is responsible for QIAGEN's NGS Knowledge offerings including HGMD, CentoMD, QIAGEN Knowledgebase, and Ingenuity Variant Analysis. Rupert was a Howard Hughes Postdoctoral Fellow in Genetics at Harvard Medical School before joining the ranks of industry.
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                                    C.E. Credits

                                    The speakers below have been approved for CME, CE, or CEU credits. To redeem your credits, locate the presentation you watched and click on the CME/CE/CEU buttons for further direction. For more general information regarding continuing education, the processes to receive credits, and the accreditation bodies, Click here


                                    Committee

                                    To download the Program Committee brochure here.


                                    • David Smith, PhD

                                      David I Smith received his B.S. in Mathematics and Molecular Biology from the University of Wisconsin in Madison. He then received his Ph.D. for the Department of Biochemistry also at the University of Wisconsin in Madison. After several postdoctoral positions he got his first ...

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                                    • Sarah Elsea

                                      Dr. Sarah H. Elsea is an Associate Professor of Molecular and Human Genetics at Baylor College of Medicine and is Senior Division Director of Biochemical Genetics at Baylor Genetics. Dr. Elsea earned a B.S. in chemistry from Missouri State University and Ph.D. in biochemistry ...

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                                    • Tatjana Matejic

                                      Tatjana is an immunologist with more than two decades of experience working at biotech and pharma companies from start-ups to large global corporations ( Pfizer,Inc. being the latest), contributing significantly to team efforts and successes of more than thirty early and clinical ...

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                                    • Khyati Shah

                                      Khyati Shah received her Ph.D. in Molecular Pharmacology from the University of the Pacific, Stockton, California. Her graduate research was completed in the lab of Jesika Faridi, Ph.D. Her work focused on the investigation of the mechanism of Akt induced tamoxifen resistance in ...

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