With nearly 9 million covered lives serviced through over 150 medical centers, the VA is one of the largest, unified Healthcare System within the United States. Embedded within this system is a large intramural research program spanning biomedical, clinical, rehabilitative and healthcare delivery research program. Just over 10 years ago, the Veterans Healthcare Administration declared a need to invest in genomic medicine both in research and healthcare delivery. Ronald M. Przygodzki, MD, was brought on to build out the genomic medicine program within the Office of Research and Development, ultimately conceptualizing and leading the efforts to develop the Million Veterans Program, the largest genomic research biobank worldwide. He currently is developing the bridge between genomic research and clinic as Director, Genomic Medicine Implementation. Dr. Laurence J. Meyer, MD, PhD, was brought on as the National Director, Genomic Medicine where he developed a nationwide telehealth genetic counseling program that services the VA Healthcare system nationwide. Currently, he is the Chief Officer, Specialty Care Services where he leads the modernization of VA healthcare. Both Ron and Larry will be presenting strategies, lessons learned and goals withn genomic medicine to provide the best healthcare to our nation's Veterans.