FEB 03, 2016 12:00 PM PST

Panel: How small things can have a big impact on research and breeding in your rodent colony

Speakers
  • Supervisor, North America, Veterinary Science, Research and Support, Envigo
    Biography
      Mandy Horn is the Supervisor of the North America Veterinary Science, Research and Support department at Envigo, and also serves on the IACUC. She received her Master of Science degree in Animal Sciences from Purdue University in 2008 with a focus on ruminant nutrition and reproduction, and began her career in the laboratory animal industry shortly thereafter. At Envigo, she is responsible for managing the North America VSRS team, including internal and external project management, model-related technical support, and health monitoring of internal colonies.
    • Global Manager of Genetic Quality and Breeding, Envigo
      Biography
        Sheri Wildt, MS, MBA is the Global Manager of Genetic Quality and Breeding for Envigo RMS. She attended Purdue University where she received her Bachelors of Science in Biology and Masters of Science in Molecular Genetics. Sheri also received her MBA with a concentration in Project Management. Prior to coming to Envigo, Sheri worked as a Research Scientist at Endocyte in West Lafayette, Indiana, where she was one of the primary scientists working on a folate-targeted molecular imaging agent used to identify tumors that express folate receptors. She has worked at Envigo RMS as their global breeding and genetics expert for 14 years. Her primary areas of expertise are in animal breeding, population genetics and oncology research.

      Abstract

      This presentation will discuss variables in rodent colony management that can affect colony breeding efficiency, rodent health, and factors that can modulate rodent models of disease.  Variables discussed will include housing and husbandry, environment and genetic background.  Differences in husbandry that may impact research studies are varied and include environment (temperature, humidity), caging conditions (bedding, enrichment, or cage position), as well as animal husbandry staff. The genetics discussion will detail the importance of genetic background in scientific research, particularly as it relates to transgenic rodent colony management and breeding. Discussions will include awareness and management of potential research variables to minimize variation and optimize reproducibility in research. The participants will gain a broader understanding of these variables and how to use this information in different situations.

      Learning Objectives:

      • Awareness and management of potential research variables not included in your study design
      • Communication between investigators, animal technicians, veterinarians, and support staff is key

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