MAR 06, 2018 8:00 AM PST

Performance assessment of RNA sequencing and expression arrays for transcriptome analysis in cancer research

Speaker
  • Research Scientist, Bioinformatics and Modelling Group, Proteome and Genome Research Unit, Department of Oncology, Luxembourg Institute of Health
    BIOGRAPHY

Abstract

DATE: March 6, 2018
TIME: 08:00am PST, 11:00am EST, 5:00pm CET

RNA sequencing and expression arrays are transcriptomics techniques used to quantify transcribed genes and their isoforms. The first part of the talk will compare RNA-seq and array performance for the analysis of differences between normal lung epithelium tissue and squamous cell carcinoma lung tumors. High concordance for protein-coding gene expression was observed between the platforms. However, much more discrepant results were obtained for the detection of less abundant transcripts, including long non-coding RNAs and alternatively spliced variants. The second part of the talk will describe the method that can help combine results from different platforms and analyze data generated from bulk heterogeneous samples, called independent component analysis.

In this webinar, the speaker will:

  • Describe the results of platform comparison for protein-coding and long non-coding genes
  • Explain the biases observed in RNA-seq and expression array platforms
  • Share insights on how deconvolution of transcriptomics data followed by machine learning can improve tumor classification

 

For Research Use Only. Not for use in diagnostic procedures.


Show Resources
You May Also Like
MAY 11, 2021 10:00 AM PDT
C.E. CREDITS
MAY 11, 2021 10:00 AM PDT
Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
SEP 14, 2021 7:00 AM PDT
C.E. CREDITS
SEP 14, 2021 7:00 AM PDT
Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...
JUN 09, 2021 7:00 AM PDT
C.E. CREDITS
JUN 09, 2021 7:00 AM PDT
Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
JUL 15, 2021 9:00 AM PDT
JUL 15, 2021 9:00 AM PDT
Date: July 15, 2021 Time: 9:00am (PDT), 12:00pm (EDT) The Pisces workflow robust, easy-to-use, end-to-end multi-omics solution for highly multiplexed targeted Spatial RNA analysis. VeranomeB...
JUN 03, 2021 12:00 PM CST
JUN 03, 2021 12:00 PM CST
DATE: June 3, 2021 TIME: 12:00pm SGT This webinar is a virtual event that focuses on utilizing the Gibco CTS Rotea System for Cell and Gene Therapy...
SEP 17, 2021 12:00 PM CST
C.E. CREDITS
SEP 17, 2021 12:00 PM CST
Date: September 16, 2021 Time: 9:00pm (PDT), 12:00am (EDT) 3D cellular models like organoids and spheroids offer an opportunity to better understand complex biology in a physiologically rele...
MAR 06, 2018 8:00 AM PST

Performance assessment of RNA sequencing and expression arrays for transcriptome analysis in cancer research


Specialty

Cancer Research

Molecular Biology

Gene Expression

Genetics

Bioinformatics

Biotechnology

Cell Biology

Genomics

Cancer Diagnostics

Molecular Diagnostics

Cell Culture

Biomarkers

Dna

Gene Sequencing

Dna Sequencing

Geography

North America55%

Europe24%

Asia8%

South America4%

Africa3%

Oceania1%

Registration Source

Website Visitors60%

WAVE Newsletter Promotion13%

Email Promotions9%

Client/Sponsor Promotions8%

Social Media Promotions8%

Website Banners1%

Job Title

Student23%

Research Scientist16%

Post Doc11%

Scientist9%

Educator/Faculty8%

Medical Laboratory Technician7%

Executive6%

Facility/Department Manager6%

Medical Doctor/Specialist5%

Lab Management4%

Biologist3%

Clinical Laboratory Scientist2%

Marketing/Sales1%

Organization

Academic Institution17%

Research Institute11%

Biotech Company7%

Clinical Laboratory7%

Hospital5%

Medical Center3%

Life Science Company3%

Medical School2%

Pharmaceutical Company2%

Government2%

Non-Profit Organization2%

Ambulatory Care1%

Industrial Company1%

Veterinary School1%

Other4%


Show Resources
Loading Comments...
Show Resources