Assistant Professor, Buck Institute for Research on Aging, Director of the Mass Spectrometry Core, Buck Institute; Adjunct Professor, USC.Biography
I am a Research Associate Professor with an independent laboratory and the Director of the Mass Spectrometry Core at the Buck Institute for Research on Aging. I am especially interested in protein chemistry and modern mass spectrometric technologies to advance the field of Proteomics mainly in the context of Aging Research. I am directly involved in a large variety of research projects (spanning neurodegenerative diseases, cancer, diabetes, mitochondrial damage, molecular mechanisms of aging, protein posttranslational modifications, bacterial pathogenesis etc.), and in mass spectrometric method development that will benefit biological projects. To date this work has resulted in 99 peer-reviewed publications. Several research projects include investigation of protein phosphorylation, glycosylation, acetylation, succinylation and other posttranslational modifications, as well as differential expression of proteins during disease and aging processes. I have collaborated on several projects specifically investigating mitochondrial acetylation and succinylation - and I have been working on different phosphorylation projects using various affinity enrichment strategies.