It has been noted by many in the community that for Precision Medicine to become a transformative reality, the underlying DNA and RNA sequence data have to become more precise. In my talk, I will highlight several examples how long and accurate sequence reads using SMRT Sequencing have been utilized in clinical research to uniquely inform about certain genetic dispositions, and how it has helped elucidate the underlying cause of certain diseases that had previously eluded their determination.
1. Understand the concept of generating long and accurate sequence reads using PacBio technology
2. Familiarize with examples for which long and accurate reads have helped elucidate genetic conditions that were previously undetermined