FEB 13, 2019 1:30 PM PST

Precision Medicine for Mice: Digital Biomarkers Transforming Drug Discovery

C.E. Credits: RACE
Speaker
  • Chief Scientific Officer, Vium
    Biography
      Laura Schaevitz has more than 20 years of experience with In vivo animal studies. As Chief Scientific Officer at Vium, she oversees the development of animal models and draws upon her experiences as a molecular and behavioral neuroscientist to direct the application of Vium's digital metrics to the animal models. In past experiences, Laura utilized a broad spectrum of mouse models including transgenic and nutrition-induced models of neurodevelopmental disorders such as autism, schizophrenia, Rett syndrome, and blindsight. Laura received her PhD in Neuroscience at Stanford University in 2006.

    Abstract

    Preclinical drug discovery is at the edge of a major transformation that promises to improve translation to the clinic through enhanced acquisition and advanced analysis of data. While an important part of the drug development process, currently preclinical studies do not always predict drug failure or success in the clinic. Limited predictive power is attributed to many factors including limited measurable parameters on a single animal, infrequent collection, and small sample sizes that are often captured under conditions that have the potential to alter the animal’s physiologic state and confound data interpretation. Digital biomarkers, captured continuously without handling, provide objective, sensitive, and clinically meaningful methods of monitoring disease and response to therapeutic interventions. This webinar reviews the the current state of digital biomarkers in preclinical studies and discusses the challenges and opportunities for more widespread adoption to improve translation of preclinical studies to the clinic.

    Learning Objectives: 

    1. Define digital biomarkers and current state in drug development
    2. Examine how high frequency capture of digital biomarkers provides objective, sensitive, and meaningful readouts of disease state and compound efficacy that may be more translatable to the clinic.
    3. Discuss challenges and opportunities for the future capture and analysis of digital biomarkers in preclinical studies


    Show Resources
    You May Also Like
    NOV 18, 2020 8:00 AM PST
    C.E. CREDITS
    NOV 18, 2020 8:00 AM PST
    DATE: November 18, 2020 TIME: 08:00am PDT We develop and implement technologies to solve some of the major bottlenecks in biomedical research. In particular, we establish new imaging approac...
    DEC 02, 2020 8:00 AM PST
    C.E. CREDITS
    DEC 02, 2020 8:00 AM PST
    DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
    NOV 16, 2020 8:00 AM PST
    C.E. CREDITS
    NOV 16, 2020 8:00 AM PST
    Date: November 16, 2020 Time: 8:00am (PST), 11:00am (EST) CRISPR screening has become the prime discovery tool in modern biomedical research and drug discovery. At the same time, most screen...
    AUG 25, 2020 8:00 AM PDT
    C.E. CREDITS
    AUG 25, 2020 8:00 AM PDT
    DATE: August 25, 2020 TIME: 8:00am PDT, 10:00am CDT, 11:00am EDT Recombinant lentivirus (LV) and adeno-associated virus (AAV) are critical components of cell and gene therapies, which show g...
    DEC 16, 2020 8:00 AM PST
    C.E. CREDITS
    DEC 16, 2020 8:00 AM PST
    Date: December 16, 2020 Time: 8:00am (PST), 11:00am (EST) Molecular imaging of living specimens offers a means to draw upon the growing body of high-throughput molecular data to better under...
    OCT 08, 2020 7:00 AM PDT
    C.E. CREDITS
    OCT 08, 2020 7:00 AM PDT
    DATE: October 8, 2020 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop thinking about ho...
    FEB 13, 2019 1:30 PM PST

    Precision Medicine for Mice: Digital Biomarkers Transforming Drug Discovery

    C.E. Credits: RACE

    Specialty

    Animal Research

    Animal Models

    Animal Sciences

    Animal Behavior

    Life Science

    Cancer Research

    Lab Animals

    Veterinary Sciences

    Immunology

    Research

    Molecular Biology

    Brain

    Cell Biology

    Animals

    Research And Development

    Geography

    Europe84%

    North America12%

    Asia2%

    Registration Source

    Website Visitors100%

    Job Title

    Research Scientist22%

    Student14%

    Medical Laboratory Technician13%

    Post Doc12%

    Medical Doctor/Specialist10%

    Scientist7%

    Clinical Laboratory Scientist4%

    Biologist3%

    Animal Care Lab Technician3%

    Educator/Faculty2%

    Executive2%

    Facility/Department Manager2%

    Veterinarian2%

    Veterinary Technician1%

    Lab Management1%

    Organization

    Academic Institution50%

    Hospital15%

    Research Institute11%

    Pharmaceutical Company4%

    Industrial Company3%

    Clinical Laboratory3%

    Medical Center2%

    Ambulatory Care2%

    Life Science Company1%

    Medical School1%

    Contract Research Organization (Cro)1%

    Manufacturer & Biotech/pharma1%

    Government/public1%

    Non-Profit Organization1%

    Other2%


    Show Resources
    Loading Comments...
    Show Resources
    Attendees
    • See more