Professor & Associate Director, Aab Cardiovascular Research Institute, University of Rochester.
Biography
Joseph Miano received his Ph.D. in Experimental Pathology from New York Medical College and did post-doctoral training with Eric Olson at the M.D. Anderson Cancer Center in Houston. His first faculty appointment was at the Medical College of Wisconsin where he worked mainly on the role of retinoids as a therapeutic for vascular diseases. He was then recruited to the University of Rochester School of Medicine and Dentistry where he is a Full Professor and Associate Director of the Aab Cardiovascular Research Institute. Dr. Miano serves as an editorial board member for several journals and is an Associate Editor of Vascular Pharmacology. He is a past Associate Editor of ATVB and Consulting Editor for Circulation Research. He is a Fellow of the American Heart Association and a member of the Vascular Cell and Molecular Biology Study Section at NIH. Current research in the Miano Lab focuses on deciphering how small snippets of code in our genome give cells exquisite control over the level of gene activity, much like a thermostat controlling the heat in a home. Passionate about new technology that drives research, Dr. Miano's lab was among the first wave of labs in 2013 to exploit the revolutionary CRISPR-Cas9 genome editing technology for purposes of altering the mouse genome and within a year, the lab generated the first CRISPR animal model carrying subtle mutations in a control element that turns on a gene.
