FEB 04, 2016 10:30 AM PST

Sex As A Biological Variable In Rodent Models

Speaker
  • Director, Division of Comparative Medicine, Office of Research Infrastructure Programs, Division of Program Coordination, Planning, and Strategic Initiatives, Office of the Director, National

Abstract

Historically, rodent disease models have mainly used a single sex or did not stratify outcomes by sex when both sexes were studied. These experimental approaches were based on the assumption that disease mechanisms or treatment effects observed in one sex would also apply to the other. However, it has recently been recognized that disease conditions and responses to therapy may differ between sexes.  Reversing the “single sex” or “no sex-stratification” approaches in rodent studies have been slow to change, partly due to male and. female animal availability issues and costs, insufficient investigator knowledge of reproductive and gender biology, limits on research funding, and sex-related laboratory animal management concerns. This session will provide an opportunity to educate participants how consideration of sex as a biological variable might impact design of experimental studies with rodent models in terms of science and laboratory animal care and management.

Learning Objectives: 

  1. Understand the difference between sex and gender and why one needs to pay attention to sex as a biological variable in biomedical research with rodent models
  2. Recognize common myths and urban legends about sex as a biological variable and appreciate when inclusion of one or both sexes is needed in studies with rodent models 
  3. Become familiar with general reproductive biology principles, experimental strategies, investigative techniques, and available resources when contemplating sex as a biological variable in rodent models

Show Resources
You May Also Like
SEP 14, 2021 7:00 AM PDT
Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
C.E. CREDITS
SEP 14, 2021 7:00 AM PDT
Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...
MAY 11, 2021 10:00 AM PDT
C.E. CREDITS
MAY 11, 2021 10:00 AM PDT
Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
FEB 24, 2021 10:00 AM PST
C.E. CREDITS
FEB 24, 2021 10:00 AM PST
DATE: February 24, 2021 TIME: 10am PST Automated lab instruments such as liquid handlers and cell sorters are increasingly common in all types of laboratories, driving fast results for labor...
APR 01, 2021 8:00 AM PDT
C.E. CREDITS
APR 01, 2021 8:00 AM PDT
Date: April 01, 2021 Time: 8:00am (PST), 11:00am (EST) Generating therapeutic antibodies is far more challenging than obtaining antibodies that merely recognize their targets. Engineering po...
MAR 18, 2021 8:00 AM PDT
C.E. CREDITS
MAR 18, 2021 8:00 AM PDT
DATE: March 18, 2021 TIME: 8:00am PDT Sequencing of bulk cells, single cells, and nuclei is opening doors in the understanding of complex biological processes....
MAR 16, 2021 10:00 AM PDT
C.E. CREDITS
MAR 16, 2021 10:00 AM PDT
Date: March 16, 2021 Time: 10:00am (PST) Scientific progress and breakthroughs today are often too expensive for most institutions to acquire. Each year, the National Institutes of Health (N...
FEB 04, 2016 10:30 AM PST

Sex As A Biological Variable In Rodent Models


Specialty

Animal Models

Animal Behavior

Animal Research

Cancer

T-Cells

Immunology

Research

Animals

Research And Development

Life Science

Antibodies

Flow Cytometry

Immuno-Oncology

Lab Animals

Dna Sequencing

Geography

Europe73%

North America9%

Registration Source

Website Visitors91%

Job Title

Medical Laboratory Technician38%

Scientist25%

Student13%

Executive13%

Lab Management13%

Organization

Academic Institution27%

Pharmaceutical Company18%

Government/public9%

Non-Profit Organization9%

Hospital9%

Biotech Company9%


Show Resources
Loading Comments...
Show Resources