Gonçalo started his lab in 2012, focusing on the molecular mechanisms defining the epigenetic state of cells of the oligodendrocyte lineage. His research group is particularly focused on how interplay between transcription factors, non-coding RNAs and chromatin modifying enzymes contributes to the transition between epigenetic states in oligodendrocyte precursor cells- with the aim to design epigenetic based-therapies to induce regeneration (remyelination) in demyelinating diseases, such as multiple sclerosis. Dr Amit Zeisel is postdoc fellow in the Department of Medical Biochemistry and Biophysics at the Karolinska Institutet in Stockholm, Sweden. Amit received is PhD in systems biology from Weizmann Instititue of Science under the supervision of Prof. Eytan Domany.
For the last three years, he has been a postdoc in the lab of Sten Linnarsson, were he developed protocols and computational tools for the analysis of single-cell RNA-seq.