Biologist, Biosystems & Biomaterials Division
Biography
Dr. Simon is a biologist in the Biomaterials Group at the National Institute of Standards and Technology. We aim to develop reliable tools and standards for measuring the properties of cells, biomaterials, scaffolds and tissue-engineered constructs. As regenerative medicine moves from a research endeavor to a viable industry that benefits patients and U.S. commerce, reliable methods for assessing product consistency and quality are required. In one of our projects, we are working with Kapil Bharti (NIH) to establish simple, robust methods for characterizing tissue-engineered retinal pigment epithelium for use in a clinical trial to treat age-related macular degeneration. In another project, we are working with Pamela Robey (NIH) to improve sampling in measurements of osteogenesis induced by stem cell/scaffold formulations in an ectopic bone mouse model. We also work with computer scientists to develop image analysis and bioinformatics methods for assessing the physical properties of 3D tissue scaffolds and how they influence cell function. Dr. Simon is Chair of ASTM Committee F04.43 "Cells and Tissue-Engineered Constructs" where documentary standards are being developed to support the development of tissue-engineered medical products. He earned a B.S. in Biology from Bucknell University and a Ph.D. in Biochemistry from University of Virginia where his thesis focused on signal transduction during human platelet aggregation. He trained as a post-doctoral fellow in NIST Polymers Division and became a staff scientist at NIST in 2003. Dr. Simon is active in the Society for Biomaterials, ISO, TERMIS and Phacilitate, and is on the editorial board for "Biomaterials" and "Journal of Biomedical Materials Research Part B - Applied Biomaterials".
