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FEB 20, 2017 8:00 AM PST

High throughput process development - optimizing a mAb chromatography polishing step

Speaker
  • Product Manager Design, GE Healthcare Life Sciences
    Biography
      Peter Hagwall has a scientific background in process analytical technologies and surface chemistry. For the last 5 years, Peter has been active as product manager for chromatography resins and focus on tools and methodologies for process development and characterization

    Abstract

    Development of robust purification processes requires significant time and resources. In addition, steadily increasing demands from regulatory authorities for better understanding and control of manufacturing processes put even more pressure on development work. High-throughput process development (HTPD) shortens development time at the same time as it increases the amount of information available during early process development.

    Here we will present a case study using high throughput process development tools optimizing process conditions for a mAb polishing step using a multimodal chromatography resin (Capto MMC ImpRes)


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