OCT 11, 2018 8:00 AM EDT

Tissue Biomarker Analysis: A Practical Approach for Translational Research

Sponsored by: PerkinElmer, Inc.
Speakers

Abstract

DATE: October 11, 2018
TIME: 8:00AM PDT, 11:00AM EDT, 4:00PM BST, 5:00PM CEST

Simultaneous quantitation of 6 or more biomarkers in intact tissue specimens holds the key to many questions concerning the biological basis of health and disease by allowing complex cellular interactions to be captured and analyzed. However, reliable detection remains elusive due to technical challenges from many sources, including antibody cross reactivity, difficulty in balancing signals from rare and abundant targets, tissue autofluorescence and interference between fluorophores, especially for co-localized targets.

In this webinar application scientists from PerkinElmer will present a practical and validated method for highly multiplexed tissue biomarker analysis that addresses many of these challenges. Opal™ staining is an antibody-agnostic technique, which produces highly specific and reproducible results and when combined with multispectral imaging systems, such as Vectra®, is able to detect eight or more biomarkers simultaneously in one tissue section. Simultaneous detection of multiple antigens on a single tissue with multispectral imaging and analysis reveals spatial relationships between cells with the resolution needed for high-precision proximity analysis and detection of intracellular localization of targeted antigens. By elucidating the relationships between cells, Opal staining allows you to see intercellular relationships in context of the microenvironment.  
 

Learning Objectives:

  • How to overcome key challenges inherent in multiplex biomarker analysis 
  • Practical and validated approaches to multiplex IHC staining
  • Why multispectral imaging is important for generating high quality data 

  • Methods for analyzing relationships between cells  


Show Resources
You May Also Like
MAY 11, 2021 10:00 AM PDT
C.E. CREDITS
MAY 11, 2021 10:00 AM PDT
Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
JUN 09, 2021 7:00 AM PDT
C.E. CREDITS
JUN 09, 2021 7:00 AM PDT
Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
APR 21, 2021 5:00 PM CEST
APR 21, 2021 5:00 PM CEST
Date: April 21, 2021 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Spatial Answers Trilogy - Spatial Answers in Immunology Immunology Researchers share their Spatial Discoveries in SARS-C...
JUL 15, 2021 9:00 AM PDT
Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
JUL 15, 2021 9:00 AM PDT
Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
Date: July 15, 2021 Time: 9:00am (PDT), 12:00pm (EDT) The Pisces workflow robust, easy-to-use, end-to-end multi-omics solution for highly multiplexed targeted Spatial RNA analysis. VeranomeB...
APR 01, 2021 8:00 AM PDT
C.E. CREDITS
APR 01, 2021 8:00 AM PDT
Date: April 01, 2021 Time: 8:00am (PST), 11:00am (EST) Generating therapeutic antibodies is far more challenging than obtaining antibodies that merely recognize their targets. Engineering po...
MAR 16, 2021 10:00 AM PDT
C.E. CREDITS
MAR 16, 2021 10:00 AM PDT
Date: March 16, 2021 Time: 10:00am (PST) Scientific progress and breakthroughs today are often too expensive for most institutions to acquire. Each year, the National Institutes of Health (N...
OCT 11, 2018 8:00 AM EDT

Tissue Biomarker Analysis: A Practical Approach for Translational Research

Sponsored by: PerkinElmer, Inc.

Specialty

Cancer Research

Cell Biology

Biomarkers

Molecular Biology

Biotechnology

Cell Culture

Immunology

Cancer Diagnostics

Cancer Therapeutics

Biochemistry

Antibodies

Cell Signaling / Transduction

Clinical Research

Gene Expression

Molecular Diagnostics

Geography

North America43%

Europe22%

Asia16%

Africa9%

South America7%

Oceania3%

Registration Source

Website Visitors60%

Email Promotions23%

WAVE Newsletter Promotion8%

Website Banners3%

Social Media Promotions2%

Trending Newsletter Promotion1%

Other2%

Job Title

Student22%

Research Scientist18%

Scientist10%

Educator/Faculty9%

Executive8%

Medical Doctor/Specialist6%

Facility/Department Manager6%

Medical Laboratory Technician5%

Post Doc5%

Lab Management2%

Clinical Laboratory Scientist2%

Marketing/Sales1%

Consultant1%

Biologist1%

QC/QA1%

Organization

Academic Institution23%

Research Institute13%

Biotech Company11%

Hospital7%

Medical School6%

Government6%

Clinical Laboratory6%

Pharmaceutical Company5%

Life Science Company4%

Medical Center3%

Industrial Company1%

Medical Device Company1%

Non-Profit Organization1%

Contract Research Organization (Cro)1%

Other7%


Show Resources
Loading Comments...
Show Resources
Attendees
  • See more