FEB 24, 2017 8:00 AM PST

WEBINAR: Validating the Routine Use of High Resolution QTOF LC-MS/MS for the Analysis of Pesticides in Baby Food

Sponsored by: SCIEX
Speaker
  • Professor of Analytical Chemistry, University of Almeria, Spain & Head of the European Union Reference Laboratory (EURL) for Pesticide Residues in Fruits and Vegetables
    Biography
      Prof. Amadeo R. Fernández-Alba is the Director of the EURL Reference Laboratory for pesticide residues in fruits and vegetables (EURL-FV, www.eurl-pesticides.eu). He has participated as a researcher / director contracts on more than 15 EU projects, 30 competitive Spanish research projects and more than 50 research contracts with companies. He has directed 15 PhD theses and 6 are currently in development. More than 40 doctoral students and researchers from EU countries and outside the EU have developed stays in this group, actively participating in the development of research projects. He has 22 years of experience in university teaching, masters and doctoral programs.
      He is director and founder of the research group "Pesticide Residues" This group was founded in 1996 with the aim of giving impetus to the marketing of almerienses products (fruits and vegetables) in Europe. He is the author of over 256 scientific papers in ISI-JCR journals related to quality, food safety and environmental protection against chemical contamination.

    Abstract

    DATE: February 24th, 2017
    TIME: 8:00AM PT, 11:00AM ET

    Pesticide residue analysis of baby food products represents a challenge for routine control laboratories as consequence of the stringent EU MRL in place (EC/125/2006 Directive). It makes it necessary to reach low LOQ in the validated methods for a specific group of pesticides.


    The application of liquid chromatography coupled with quadrupole time of flight working in SWATH® mode allows the detection of such analytical performance avoiding matrix interferences in full scan mode.
    SWATH mode was evaluated by selecting various mass segments and 20 windows considered as optimum. Limits of quantification close to 1 ug/kg, good reproducibility (< 15%) with large linear ranges for all LC amenable pesticides included in the regulation. Additionally facilities such as easy inclusion of new target compounds in the scope and retrospective analysis were also checked. The validated methods has been applied to baby food real samples with good results.

     

    Learning objective 1: Discover a new advanced workflow for pesticide screening

    Learning Objective 2: See how a full scan work-flow can perform quantification close to 1ug/kg 

    Learning Objective 3: Find out how High Resolution Mass Spec (HRMS) handles samples with complex matrices


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