DATE: February 24th, 2017
TIME: 8:00AM PT, 11:00AM ET
Pesticide residue analysis of baby food products represents a challenge for routine control laboratories as consequence of the stringent EU MRL in place (EC/125/2006 Directive). It makes it necessary to reach low LOQ in the validated methods for a specific group of pesticides.
The application of liquid chromatography coupled with quadrupole time of flight working in SWATH® mode allows the detection of such analytical performance avoiding matrix interferences in full scan mode.
SWATH mode was evaluated by selecting various mass segments and 20 windows considered as optimum. Limits of quantification close to 1 ug/kg, good reproducibility (< 15%) with large linear ranges for all LC amenable pesticides included in the regulation. Additionally facilities such as easy inclusion of new target compounds in the scope and retrospective analysis were also checked. The validated methods has been applied to baby food real samples with good results.
Learning objective 1: Discover a new advanced workflow for pesticide screening
Learning Objective 2: See how a full scan work-flow can perform quantification close to 1ug/kg
Learning Objective 3: Find out how High Resolution Mass Spec (HRMS) handles samples with complex matrices