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Genome engineers can leverage an ever-expanding array of biological and computational tools to make targeted genetic changes. Maintaining and optimizing components ranging from reagent desig...
As we further understand the complexity and diversity of cellular states, it is becoming necessary for a cellular engineering toolbox, consisting of molecular tools that allow control over c...
Nucleic acid analysis is crucial for the diagnostics of infectious diseases such as COVID-19. CRISPR/Cas technology, beyond its broad application in gene editing, features, in this regard, a...
Clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated protein 13 (Cas13) has been rapidly developed for nucleic-acid-based diagnostics by using its chara...
Date: November 2, 2022 Time: 7:00am (PDT), 10:00pm (EDT), 4:00pm (CEST) As part of the immune response, inflammation plays a vital role in the host defense and is dictated by the balance bet...
Traditional methods for pathogen detection are often expensive and time-consuming and requires a well-equipped laboratory. Here we present a low-cost, deployable paper-based biosensor device...
CRISPR/Cas gene editing technology has rapidly evolved over the last decade. Its versatility extends from creating targeted research-use disease models in cells and animals, to high-throughp...
The Cas9 from Francisella novicida (FnCas9) has unique properties of target identification and engagement in terms of specificity, nature of double strand break as well as length of guide RN...
Cancer, as a disease, starts with a change in the genome that results in the downregulation of genes involved in "normal" cell behavior. This genetic change can either be induced b...
The clustered regularly interspaced short palindromic repeat (CRISPR) genome-editing revolution established the beginning of a new era in life sciences. I will report the role of state-of-th...
Rapid, accurate and frequent detection of the RNA of SARS-CoV-2 and of serological host antibodies to the virus would facilitate the determination of the immune status of individuals who hav...
Simple and sensitive nucleic acid-based molecular detection plays a crucial role in the early diagnosis of infectious diseases and the rapid screening of cancers. CRISPR technology has recen...
The COVID-19 pandemic highlights the need for diagnostics that can be rapidly adapted and deployed in a variety of settings. Several SARS-CoV-2 variants have shown worrisome effects on vacci...
CRISPR has revolutionized the biosciences over the past decade. The RNA-targeting CRISPR effector protein Cas13, discovered in 2016, opened up a myriad of new applications for CRISPR-based t...
The CRISPR revolution has begun and shows no signs of slowing down. CRISPR-Cas nuclease-based genome editing strategies hold great promise for the treatment of genetic disorders. However, a...
My laboratory uses tools from pharmacology, genomics, and cell signaling to study two key aspects of cancer biology. First, we seek to understand how oncogenic signals, altered metabolic sta...
Date: November 01, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 6:00pm (CET) Our laboratory developed the Pig-a gene mutation assay as a means to simply and reliably evaluate the potential mutage...
Date: November 1, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 5:00pm (CET) Rapid and efficient organism identification and antimicrobial susceptibility reports are paramount for patient survival...
Date: November 01, 2022 Time: 8:00am (PDT), 1:00am (EDT), 4:00pm (CEST) This webinar will focus on sub-micron particle analysis utilizing high sensitivity violet side scatter detection. We w...
Date: November 01, 2022 Time: 7:00am (PDT), 10:00am (EDT), 3:00pm (CET) Molecular imaging of living specimens offers a means to draw upon the growing body of high-throughput molecular data t...
Date: November 01, 2022 Time: 6:00am (PDT), 9:00pm (EDT), 3:00pm (CEST) Density gradient ultracentrifugation is known to provide high purity and high yield viral vector separations required...
Date: October 26, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) To control and monitor the epidemiology and diffusion of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV...
Date: October 26, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Immunotherapy has transformed the treatment of metastatic and recurrent solid tumors. Advances in technology in the pa...
Date: October 26, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) In this webinar, attendees will be provided an overview of the technologies that currently exist for bacterial endotox...
Date: October 26, 2022 Time: 6:00am (PDT), 9:00pm (EDT), 3:00pm (CEST) In the global fight toward Hepatitis C elimination, hear insights into how to build a cost-effective screening program...
Date: October 25, 2022 Time: 11:00am (PST), 2:00pm (EST), 8:00pm (CEST) Candida auris is a multi-drug resistant yeast that continues to be a global threat for infection and transmission in h...