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Solute carriers include numerous uptake transporters that serve as major regulators of drug absorption, disposition, and clearance. Indeed, drug interactions or genetic variation that alter...
Coronavirus Disease 2019 (COVID-19) has driven the use of nucleic acid testing technology in clinical testing. There is a growing need for point-of-care testing (POCT)......
The effect of long-term mixed-waste contamination, particularly uranium and nitrate, on the microbial community in the terrestrial subsurface at the Oak Ridge Integrated Field Research Chall...
The last 20 years have seen an explosion of genetic information and data. New technological advances have made it faster and less expensive to understand the human genomes but most of those...
mRNA vaccines represent a pivotal innovation in prophylactic healthcare, offering a rapid response to emerging infectious diseases. Leveraging the cellular machinery to produce antigenic pro...
In the ever-evolving landscape of cancer therapy, immune checkpoint inhibitors have emerged as promising avenues for therapeutic antibody development. Our presentation will share GenScript...
Efficient protein turnover is essential for cell homeostasis and organ function. Loss of proteostasis is a hallmark of aging, which culminates as a severe reduction in protein turnover rates...
Disability activists have sometimes claimed their disability has actually increased their well-being. Some even say they would reject a cure to keep these gains. Yet, these same activists of...
The Irvine CubeSat STEM Program (ICSP) is a collaboration between Irvine Public Schools Foundation, and Irvine and Tustin Unified school districts that provides teams of students from all si...
Cannabis edibles and orally administered oils act slowly and unreliably because the incorporated cannabinoids do not dissolve in water. Similar poor performance profiles are observed for oth...
In the past decade, gene editing has been increasingly emphasized as an essential tool for therapy development. This has led to significant scientific advances in understanding disease mecha...
Molecular diagnostics based on clustered regularly interspaced short palindromic repeats (CRISPR) enzyme systems have been the subject of intense research....
Digital PCR (dPCR) has emerged as a powerful tool in genetic analysis, offering improved precision, sensitivity, and accuracy compared to traditional methods. In this webinar, we will provid...
Prostate cancer (PCa) affects one in nine men and is the most diagnosed solid tumor cancer among men in the United States. The introduction of the prostate-specific antigen (PSA) biomarker b...
When building your own infectious disease molecular panels there are many paths to consider. In this interview, we ask Marcus Cognetti and Dr. Ari Frenkel what approach is required to create...
Learning Objevtives: 1. Demonstrate Knowledge with gene editing, microfluidics and non-viral delivery methods. 2. Review the uses of a low-volume high-throughput transfection platform for ge...
The elegant and well-orchestrated molecular players responsible for normal neurodevelopment harbor the capacity for detrimental repercussions if mis-expressed at the wrong time, or in the wr...
This talk will focus on doing method validation work in an environment where data is gathered from laboratory information system and chromatography data system. We’ll see how these sys...
Research on decomposition odor has evolved significantly since the first introduction of this concept in the literature in 2004. This work is foundational to understanding several areas of f...
Rapid screening and speed of scale-up in protein therapeutics are critical factors in today’s immuno-oncology workflow. The ability to swiftly develop novel therapies often depends on...
T-cells targeting shared oncogenic mutations can induce durable tumor regression in epithelial cancer patients. Such T cells can be detected in tumor-infiltrating lymphocytes and peripheral...
We are developing the three-banded panther worm Hofstenia miamia as a new model system for neuroscience. Hofstenia is a rare, lab-tractable member of a lineage of early-branching marine inve...
High-resolution, 3D imaging enabled depth filters, chromatography columns and sterile filters to be analysed across multiple length scales. Generating a geometry-based database enabled struc...
Smartphone-based optical imaging and sensing devices are among the next-generation biosensors that have shown great potential to transform the field of point-of-care (POC) diagnostics....
Cancer is the #1 cause of death by disease in children. Over the last few decades, the survival rates for children with cancer have improved. These gains have been made by brilliant dedicate...
Many clinically approved drugs that are prescribed to modulate human physiology are also potent antimicrobials at physiological concentrations. Recent systematic studies indicate that bacter...