Date: September 29, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) Development and evolution are controlled, to a large degree, by regions of genomic DNA called enhancers that encode...
C9orf72 repeat expansions cause inherited amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD) and result in both loss of C9orf72 protein expression and production of potentially...
In June 2022, the ICH released the first draft of its harmonized global Drug Interaction Studies Guideline (M12). The guideline is the result of several meetings of the Expert Working Group...
Date: November 4, 2021 Time: 8:00am (PDT), 11:00am (EDT) The promise of tissue clearing techniques in combination with 3D-immunofluorescence (IF) microscopy is revolutionary. Complex biologi...
Date: September 21, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) This talk aims to describe a popular workflow that profiles specific brain cell types in healthy and diseased post-m...
Free light chains, kappa (κ) lambda (λ), are produced by plasma cells and known to be an important marker in patients with Multiple Myeloma and AL Amyloidosis. The precursor con...
Translational research strives to identify, verify, and validate biomarker candidates that can be used in clinical settings to collectively stratify biology. With the recent introduction of...
Immune checkpoint blockade (ICB) targeting T cells has enhanced clinical outcomes in patients with renal and bladder cancers; however, response rates remain limited, particularly in cases of...
B cell responses within pancreatic ductal adenocarcinoma (PDAC) tumors are associated with improved patient outcomes, yet the specific triggering antigens remain largely unknown. In this web...
Breast cancer is the most common cancer diagnosed in women and the second leading cause of female cancer death in the United States. In the last 25 years, the number of therapeutic options f...