mouse monoclonal IgA; ICAM-2 Antibody (F-5) is an IgA κ mouse monoclonal ICAM-2 antibody (also designated ICAM-2 antibody) that detects the ICAM-2 protein of mouse, rat and human origin by WB, IP, IF and FCM. ICAM-2 Antibody (F-5) is available as both the non-conjugated anti-ICAM-2 antibody form, as well as multiple conjugated forms of anti-ICAM-2 antibody, including PE, FITC. Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play important, yet separate, roles in embryogenesis and development. The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily and recognizes the b2a1 and b2aM Integrins. ICAM-2 functions as a ligand for lymphocyte function-associated antigen-1 (LFA-1) and is involved in leukocyte adhesion. ICAM-3 is highly expressed on the surface of human eosinophils, and when bound to ligand may inhibit eosinophil inflammatory responses and survival. ICAM-4, also known as LW glycoprotein, interacts with Integrins aLb2, aMb2, a4b1, the aV family and aIIbb3, and selective binding to different integrins may be relevant to the pathology in a number of red blood cell associated diseases. Lastly, ICAM-5, expressed on telencephalic neurons, binds CD11a/CD18 and thus may act as an adhesion molecule for leukocyte binding in the central nervous system.