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    Cancer genetics and genomics

    Cancer genetics and genomics is the study of how our genetic profiles are linked to the onset or progression of malignancies. Mutations leading to cancer can be inherited or acquired (also called somatic). Cancer genetics and genomic studies evaluate how such mutations relate to cancer. Additionally, genetic and genomic studies can determine how an individual will respond to therapy and may help determine the best course of treatment for cancer.

    Webinars

    • OCT 08, 2020 | 12:00 AM
      The biology of cancer disparities: an innate immunity story
      The biology of cancer disparities: an innate immunity story
      Cancer disparities among persons of African descent are driven by both biological and nonbiological factors. There is evidence in breast cancer that psychosocial factors (environment, socioe...
      Speaker: K. Sean Kimbro, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      1
      OCT 08, 2020 | 12:00 AM
      Transcriptome analysis of breast cancer clinical specimens with long-read sequencer
      Transcriptome analysis of breast cancer clinical specimens with...
      Changes in transcriptional regulation are thought to be one of the key drivers of carcinogenesis. Although next-generation sequencer revolutionized transcriptome analysis, there are limitati...
      Speaker: Masahito Kawazu, MD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      1
      OCT 07, 2020 | 12:00 AM
      Oncogene additivity in the PI3K pathway in cancer
      Oncogene additivity in the PI3K pathway in cancer
      Activating mutations in PIK3CA are frequent in human breast cancer, and phosphoinositide 3-kinase alpha (PI3Kα) inhibitors have been approved for therapy. To characterize determinants...
      Speaker: Neil Vasan, MD, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      2
      OCT 01, 2020 | 11:00 AM
      Vitamin B6 Addiction in Acute Myeloid Leukemia
      Vitamin B6 Addiction in Acute Myeloid Leukemia
      Date: October 1, 2020 Time: 10:00am (PTD), 1:00pm (EDT) Cancer cells rely on altered metabolism to support their proliferation. We performed a CRISPR/Cas9 functional genomic screen targeting...
      Speaker: Justin Cross
      Sponsored By: Agilent
      12 1
      SEP 30, 2020 | 12:00 PM
      Efficient Generation of Gene-edited Mouse Models and Cell Lines Using Synthetic sgRNA
      Efficient Generation of Gene-edited Mouse Models and Cell Lines...
      The CRISPR/Cas genome editing system has revolutionized nearly every aspect of the life science industry. Until recently, the most used formats for this technology have been plasmids, mRNA,...
      Speaker: Gurpreet Balrey, PhD , Peter Romanienko, PhD
      Presented at: CRISPR Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      4
      SEP 30, 2020 | 7:30 AM
      Keynote Presentation: Functionalizing Genome Editing Techniques on a Broad Range of Cellular Targets
      Keynote Presentation: Functionalizing Genome Editing Techniques...
      Genome Engineering allows the easy manipulation of genomes down to the nucleotide level. Targeted deep sequencing enables the detection and quantification of low-frequency editing events. Ho...
      Speaker: Shondra Miller, PhD/Director
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 30, 2020 | 12:00 AM
      CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
      CRISPR/Cas9 as a tool to model and study cancer - insights and...
      Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
      Speaker: Grace R. Anderson, PhD
      Presented at: CRISPR Virtual Event Series 2020
      2
      SEP 23, 2020 | 12:00 PM
      Mass Cytometry in Translational Research: Session II
      Mass Cytometry in Translational Research: Session II
      B cells and tertiary lymphoid structures (TLS) promote immunotherapy response 1:00–1:30 pm PDT Presented By: Rafet Basar, MD...
      Speaker: Handan Xiang, PhD , Pei-Yu Chen, PhD , Hiranmayi Ravichandran, MS , Rafet Basar, MD , Amir Horowitz, PhD
      Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
      2
      SEP 23, 2020 | 10:30 AM
      New Insights Gained with Imaging Mass Cytometry
      New Insights Gained with Imaging Mass Cytometry
      Speaker TBD 10:30–10:50 am PDT Exploring the immune tumor microenvironment of hepatocellular carcinoma with Imaging Mass Cytometry™ 10:50 am–11:10 am PDT Presented By: Won...
      Speaker: Won Jin Ho, MD , Melissa B. Davis, PhD
      Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
      1
      SEP 23, 2020 | 6:00 AM
      Welcome and Opening Remarks
      Welcome and Opening Remarks
      ...
      Speaker: Chris Linthwaite , Andrew Quong, PhD , Alex Cherkassky, PhD
      Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
      1
      SEP 17, 2020 | 11:00 AM
      Host and Viral Transcriptomes During COVID-19 Infection
      Host and Viral Transcriptomes During COVID-19 Infection
      In less than nine months, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has killed hundreds of thousands of people, including >23,000 in New York City (NYC) alone. The...
      Speaker: Christopher E. Mason, PhD
      Presented at: Coronavirus Series
      3
      SEP 10, 2020 | 12:00 PM
      Bacterial strain typing and genomics characterization of multi-drug resistance with QIAGEN CLC Genomics Workbench
      Bacterial strain typing and genomics characterization of multi-drug...
      In this webinar, we will present QIAGEN CLC Genomics Workbench and its utility for bacterial isolate identification, strain discrimination using core genome multi-locus typing (cgMLST) and d...
      Speaker: Jonathan Jacobs, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      Sponsored By: QIAGEN
      2
      SEP 08, 2020 | 11:00 PM
      Recombination, lineage-specific mutations and the emergence of SARS-CoV-2
      Recombination, lineage-specific mutations and the emergence of...
      The recent outbreak of SARS-CoV-2 underscores the need for understanding the evolutionary processes that drive the emergence and adaptation of zoonotic viruses in humans. Here, we show that...
      Speaker: Ioan Filip, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 08, 2020 | 9:00 AM
      Advancing Toward Personalized Medicine in Lung Cancer: A Focus on Gene Rearrangement Testing
      Advancing Toward Personalized Medicine in Lung Cancer: A Focus...
      Advances in genomics and molecular biomarker testing have led to tremendous improvements, ushering in a new era of personalized medicine especially in the oncology practice. Many of these bi...
      Speaker: Yelina Noskina, PhD
      Sponsored By: Scientific Affairs, Molecular Diagnostics at Abbott
      27 3
      SEP 02, 2020 | 7:00 AM
      Whole transcriptome in situ cell atlas reveals cellular composition and interactions in the developing human brain
      Whole transcriptome in situ cell atlas reveals cellular composition...
      DATE: September 2, 2020 TIME: 03:00pm PDT, 6:00pm EDT Spatial omics is an expanding collection of methods to examine biological molecules in their geographical context. By retaining the prec...
      Speaker: Dr. Omer Bayraktar , Pawel Zajac, Ph.D. , Dr. Rudy Van Eijsden
      Sponsored By: Illumina, NanoString Technologies
      19 3
      AUG 20, 2020 | 10:00 AM
      A Novel Method for the Isolation of Highly Pure Carcinoma Cell Populations from FFPE Tissue Improves Sensitivity for Detecting Somatic Mutations
      A Novel Method for the Isolation of Highly Pure Carcinoma Cell...
      DATE: August 20, 2020 TIME: 10:00am PT, 1:00pm ET Millions of formalin-fixed paraffin-embedded (FFPE) tissue specimens are archived annually. The enormous number of FFPE specimens available...
      Speaker: Carina Emery
      Sponsored By: Miltenyi Biotec
      21 1
      JUL 29, 2020 | 1:00 PM
      Using quantitative imaging microscopy to explore and target the molecular origins of cancer
      Using quantitative imaging microscopy to explore and target the...
      The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
      Speaker: Kirk McManus, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
      JUL 22, 2020 | 10:00 AM
      Molecular Diagnostic Solutions in a Pandemic: Planning for the 2020/2021 Flu Season with the Implementation of the ePlex® Respiratory Pathogen Panel 2
      Molecular Diagnostic Solutions in a Pandemic: Planning for the...
      DATE: July 23, 2020 TIME: 10:00 am PDT The SARS-CoV-2 pandemic has taken a toll on many sectors of the medical community. As the pandemic took a grip on the laboratory, the need for diagnost...
      Speaker: Heba Mostafa, MD, PhD, D(ABMM)
      Sponsored By: GenMark Dx
      27 13
      JUL 14, 2020 | 7:00 AM
      Cancer Genomics: What We Can Learn from Africa
      Cancer Genomics: What We Can Learn from Africa
      ABSTRACT DATE: July 14, 2020 TIME: 7:00 am PDT, 10:00 am EDT This is the second topic in the webinar series on ‘ Predictive Genomics for Population & Personalized Health ’. C...
      Speaker: Timothy Rebbeck, PhD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      27 1
      JUL 02, 2020 | 2:00 PM
      Customized Theragen PMRA chip : design history and application examples
      Customized Theragen PMRA chip : design history and application...
      Theragen Bio. (TheragenEtex Subsidiary company) has been conducted the genome-wide research and the genome-based genetic testing services. From 2007, researchers of Theragen Bio. are collabo...
      Speaker: Kyung-Won Hong, PhD
      Presented at: APJ Virtual Genetic Solutions Tour 2020
      1
      JUL 02, 2020 | 12:45 PM
      Cancer genomics research on tumor clonality and liquid biopsy
      Cancer genomics research on tumor clonality and liquid biopsy
      Most bladder cancer (BC) cases are non-muscle-invasive BC (NIBMC), which is rarely lethal. However, nearly one-fifth of NMIBC cases progress to muscle-invasive BC (MIBC), which shows a 5-yea...
      Speaker: Yosuke Hirotsu, PhD
      Presented at: APJ Virtual Genetic Solutions Tour 2020
      1
      JUL 01, 2020 | 1:30 PM
      Experience with Expanded Carrier Screening Assay
      Experience with Expanded Carrier Screening Assay
      Genetic carrier screening is a method to help couples discover whether they are at risk of passing on serious genetic disorders to their children. When carried out before conception or early...
      Speaker: Mohamed Saleem, PhD
      Presented at: APJ Virtual Genetic Solutions Tour 2020
      1
      JUL 01, 2020 | 12:15 PM
      Simplify your journey of molecular profiling with single day NGS
      Simplify your journey of molecular profiling with single day NGS
      Learn about how the new Ion Torrent Genexus System is addressing key challenges to next-generation sequencing (NGS) implementation, like hands-on time, time-to-result, user expertise, and af...
      Speaker: Jon Sherlock, PhD
      Presented at: APJ Virtual Genetic Solutions Tour 2020
      1
      JUN 26, 2020 | 8:00 AM
      Next-Generation Cytogenetics: international, multi-center study of chromosomal aberrations in constitutional diseases and leukemia with Bionano genome imaging
      Next-Generation Cytogenetics: international, multi-center study...
      DATE: June 26, 2020 TIME: 8:00am PT Structural variants (SVs) are an important source of genetic variation in the human genome and they are involved in a multitude of human diseases as well...
      Speaker: Alexander Hoischen , Laila El Khattabi
      Sponsored By: Bionano
      16
    OCT 08, 2020 | 12:00 AM
    The biology of cancer disparities: an innate immunity story
    The biology of cancer disparities: an innate immunity story
    Cancer disparities among persons of African descent are driven by both biological and nonbiological factors. There is evidence in breast cancer that psychosocial factors (environment, socioe...
    Speaker: K. Sean Kimbro, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    1
    OCT 08, 2020 | 12:00 AM
    Transcriptome analysis of breast cancer clinical specimens with long-read sequencer
    Transcriptome analysis of breast cancer clinical specimens with...
    Changes in transcriptional regulation are thought to be one of the key drivers of carcinogenesis. Although next-generation sequencer revolutionized transcriptome analysis, there are limitati...
    Speaker: Masahito Kawazu, MD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    1
    OCT 07, 2020 | 12:00 AM
    Oncogene additivity in the PI3K pathway in cancer
    Oncogene additivity in the PI3K pathway in cancer
    Activating mutations in PIK3CA are frequent in human breast cancer, and phosphoinositide 3-kinase alpha (PI3Kα) inhibitors have been approved for therapy. To characterize determinants...
    Speaker: Neil Vasan, MD, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    2
    OCT 01, 2020 | 11:00 AM
    Vitamin B6 Addiction in Acute Myeloid Leukemia
    Vitamin B6 Addiction in Acute Myeloid Leukemia
    Date: October 1, 2020 Time: 10:00am (PTD), 1:00pm (EDT) Cancer cells rely on altered metabolism to support their proliferation. We performed a CRISPR/Cas9 functional genomic screen targeting...
    Speaker: Justin Cross
    Sponsored By: Agilent
    12 1
    SEP 30, 2020 | 12:00 PM
    Efficient Generation of Gene-edited Mouse Models and Cell Lines Using Synthetic sgRNA
    Efficient Generation of Gene-edited Mouse Models and Cell Lines...
    The CRISPR/Cas genome editing system has revolutionized nearly every aspect of the life science industry. Until recently, the most used formats for this technology have been plasmids, mRNA,...
    Speaker: Gurpreet Balrey, PhD , Peter Romanienko, PhD
    Presented at: CRISPR Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    4
     
     
  • SEP 30, 2020 | 7:30 AM
    Keynote Presentation: Functionalizing Genome Editing Techniques on a Broad Range of Cellular Targets
    Keynote Presentation: Functionalizing Genome Editing Techniques...
    Genome Engineering allows the easy manipulation of genomes down to the nucleotide level. Targeted deep sequencing enables the detection and quantification of low-frequency editing events. Ho...
    Speaker: Shondra Miller, PhD/Director
    Presented at: CRISPR Virtual Event Series 2020
    1
    SEP 30, 2020 | 12:00 AM
    CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
    CRISPR/Cas9 as a tool to model and study cancer - insights and...
    Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
    Speaker: Grace R. Anderson, PhD
    Presented at: CRISPR Virtual Event Series 2020
    2
    SEP 23, 2020 | 12:00 PM
    Mass Cytometry in Translational Research: Session II
    Mass Cytometry in Translational Research: Session II
    B cells and tertiary lymphoid structures (TLS) promote immunotherapy response 1:00–1:30 pm PDT Presented By: Rafet Basar, MD...
    Speaker: Handan Xiang, PhD , Pei-Yu Chen, PhD , Hiranmayi Ravichandran, MS , Rafet Basar, MD , Amir Horowitz, PhD
    Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
    2
    SEP 23, 2020 | 10:30 AM
    New Insights Gained with Imaging Mass Cytometry
    New Insights Gained with Imaging Mass Cytometry
    Speaker TBD 10:30–10:50 am PDT Exploring the immune tumor microenvironment of hepatocellular carcinoma with Imaging Mass Cytometry™ 10:50 am–11:10 am PDT Presented By: Won...
    Speaker: Won Jin Ho, MD , Melissa B. Davis, PhD
    Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
    1
    SEP 23, 2020 | 6:00 AM
    Welcome and Opening Remarks
    Welcome and Opening Remarks
    ...
    Speaker: Chris Linthwaite , Andrew Quong, PhD , Alex Cherkassky, PhD
    Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
    1
     
     
  • SEP 17, 2020 | 11:00 AM
    Host and Viral Transcriptomes During COVID-19 Infection
    Host and Viral Transcriptomes During COVID-19 Infection
    In less than nine months, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has killed hundreds of thousands of people, including >23,000 in New York City (NYC) alone. The...
    Speaker: Christopher E. Mason, PhD
    Presented at: Coronavirus Series
    3
    SEP 10, 2020 | 12:00 PM
    Bacterial strain typing and genomics characterization of multi-drug resistance with QIAGEN CLC Genomics Workbench
    Bacterial strain typing and genomics characterization of multi-drug...
    In this webinar, we will present QIAGEN CLC Genomics Workbench and its utility for bacterial isolate identification, strain discrimination using core genome multi-locus typing (cgMLST) and d...
    Speaker: Jonathan Jacobs, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    Sponsored By: QIAGEN
    2
    SEP 08, 2020 | 11:00 PM
    Recombination, lineage-specific mutations and the emergence of SARS-CoV-2
    Recombination, lineage-specific mutations and the emergence of...
    The recent outbreak of SARS-CoV-2 underscores the need for understanding the evolutionary processes that drive the emergence and adaptation of zoonotic viruses in humans. Here, we show that...
    Speaker: Ioan Filip, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 08, 2020 | 9:00 AM
    Advancing Toward Personalized Medicine in Lung Cancer: A Focus on Gene Rearrangement Testing
    Advancing Toward Personalized Medicine in Lung Cancer: A Focus...
    Advances in genomics and molecular biomarker testing have led to tremendous improvements, ushering in a new era of personalized medicine especially in the oncology practice. Many of these bi...
    Speaker: Yelina Noskina, PhD
    Sponsored By: Scientific Affairs, Molecular Diagnostics at Abbott
    27 3
    SEP 02, 2020 | 7:00 AM
    Whole transcriptome in situ cell atlas reveals cellular composition and interactions in the developing human brain
    Whole transcriptome in situ cell atlas reveals cellular composition...
    DATE: September 2, 2020 TIME: 03:00pm PDT, 6:00pm EDT Spatial omics is an expanding collection of methods to examine biological molecules in their geographical context. By retaining the prec...
    Speaker: Dr. Omer Bayraktar , Pawel Zajac, Ph.D. , Dr. Rudy Van Eijsden
    Sponsored By: Illumina, NanoString Technologies
    19 3
     
     
  • AUG 20, 2020 | 10:00 AM
    A Novel Method for the Isolation of Highly Pure Carcinoma Cell Populations from FFPE Tissue Improves Sensitivity for Detecting Somatic Mutations
    A Novel Method for the Isolation of Highly Pure Carcinoma Cell...
    DATE: August 20, 2020 TIME: 10:00am PT, 1:00pm ET Millions of formalin-fixed paraffin-embedded (FFPE) tissue specimens are archived annually. The enormous number of FFPE specimens available...
    Speaker: Carina Emery
    Sponsored By: Miltenyi Biotec
    21 1
    JUL 29, 2020 | 1:00 PM
    Using quantitative imaging microscopy to explore and target the molecular origins of cancer
    Using quantitative imaging microscopy to explore and target the...
    The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
    Speaker: Kirk McManus, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
    JUL 22, 2020 | 10:00 AM
    Molecular Diagnostic Solutions in a Pandemic: Planning for the 2020/2021 Flu Season with the Implementation of the ePlex® Respiratory Pathogen Panel 2
    Molecular Diagnostic Solutions in a Pandemic: Planning for the...
    DATE: July 23, 2020 TIME: 10:00 am PDT The SARS-CoV-2 pandemic has taken a toll on many sectors of the medical community. As the pandemic took a grip on the laboratory, the need for diagnost...
    Speaker: Heba Mostafa, MD, PhD, D(ABMM)
    Sponsored By: GenMark Dx
    27 13
    JUL 14, 2020 | 7:00 AM
    Cancer Genomics: What We Can Learn from Africa
    Cancer Genomics: What We Can Learn from Africa
    ABSTRACT DATE: July 14, 2020 TIME: 7:00 am PDT, 10:00 am EDT This is the second topic in the webinar series on ‘ Predictive Genomics for Population & Personalized Health ’. C...
    Speaker: Timothy Rebbeck, PhD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    27 1
    JUL 02, 2020 | 2:00 PM
    Customized Theragen PMRA chip : design history and application examples
    Customized Theragen PMRA chip : design history and application...
    Theragen Bio. (TheragenEtex Subsidiary company) has been conducted the genome-wide research and the genome-based genetic testing services. From 2007, researchers of Theragen Bio. are collabo...
    Speaker: Kyung-Won Hong, PhD
    Presented at: APJ Virtual Genetic Solutions Tour 2020
    1
     
     
  • JUL 02, 2020 | 12:45 PM
    Cancer genomics research on tumor clonality and liquid biopsy
    Cancer genomics research on tumor clonality and liquid biopsy
    Most bladder cancer (BC) cases are non-muscle-invasive BC (NIBMC), which is rarely lethal. However, nearly one-fifth of NMIBC cases progress to muscle-invasive BC (MIBC), which shows a 5-yea...
    Speaker: Yosuke Hirotsu, PhD
    Presented at: APJ Virtual Genetic Solutions Tour 2020
    1
    JUL 01, 2020 | 1:30 PM
    Experience with Expanded Carrier Screening Assay
    Experience with Expanded Carrier Screening Assay
    Genetic carrier screening is a method to help couples discover whether they are at risk of passing on serious genetic disorders to their children. When carried out before conception or early...
    Speaker: Mohamed Saleem, PhD
    Presented at: APJ Virtual Genetic Solutions Tour 2020
    1
    JUL 01, 2020 | 12:15 PM
    Simplify your journey of molecular profiling with single day NGS
    Simplify your journey of molecular profiling with single day NGS
    Learn about how the new Ion Torrent Genexus System is addressing key challenges to next-generation sequencing (NGS) implementation, like hands-on time, time-to-result, user expertise, and af...
    Speaker: Jon Sherlock, PhD
    Presented at: APJ Virtual Genetic Solutions Tour 2020
    1
    JUN 26, 2020 | 8:00 AM
    Next-Generation Cytogenetics: international, multi-center study of chromosomal aberrations in constitutional diseases and leukemia with Bionano genome imaging
    Next-Generation Cytogenetics: international, multi-center study...
    DATE: June 26, 2020 TIME: 8:00am PT Structural variants (SVs) are an important source of genetic variation in the human genome and they are involved in a multitude of human diseases as well...
    Speaker: Alexander Hoischen , Laila El Khattabi
    Sponsored By: Bionano
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