Genetics and Genomics 2018

NanoString Technologies (NASDAQ: NSTG) is a publicly held provider of life science tools for translational research and molecular diagnostics. The company's technology enables a wide variety of basic research, translational medicine and in vitro diagnostics applications ... NanoString's products are based on a novel digital molecular barcoding technology invented at the Institute for Systems Biology (ISB) in Seattle under direction of Dr. Leroy Hood. The company was founded in 2003 with an exclusive license to develop and market the technology. In 2008, NanoString launched its first commercial instrument system and began international sales operations with its first multiplexed assays for gene expression analysis. In 2010, the company launched new applications for the system to support microRNA analysis and copy number variation detection, and in 2013 launched Prosigna®, its first in vitro diagnostic product for prognosis of early stage breast cancer. Organizations performing cancer research, biomarker validation and screening, and next-generation sequencing validation are rapidly adopting the nCounter® Analysis System. By providing simple, multiplexed digital profiling of single molecules, the NanoString platform represents a natural, digital downstream companion to next-generation sequencing and enables researchers to embark on studies that were previously inconceivable. Leading researchers and institutions are finding that NanoString's nCounter system provides the ideal platform on which to validate their discoveries and translate them into clinically useful diagnostic assays. The nCounter system is uniquely positioned to support translational research because it provides more reproducible results than methods requiring amplification, and generates high-quality data from the difficult sample types common in clinical research, including Formalin-Fixed Paraffin-Embedded (FFPE) tissues. In addition to continuing to extend the applications for the nCounter system in the discovery, target validation and routine testing segments of the genomics research market, the company's goal is to become the platform of choice for diagnostic testing based on multiplexed gene signatures that can be offered in hospitals and pathology laboratories worldwide, following appropriate regulatory approvals. These two synergistic areas of business focus provide researchers with a seamless transition from discovery to diagnostics.

Agilent (www.agilent.com) is a leader in life sciences, clinical research, diagnostics and applied chemical markets. With over 11,000 employees worldwide, the company provides laboratories worldwide with instruments, services, consumables, applications and expertise, enabling ... customers to gain the insights they seek. Agilent's expertise and trusted collaboration give them the highest confidence in our solutions. Agilent focuses its expertise on six key markets, where we help our customers achieve their goals: • Food: Agilent products can help ensure that our global food supply is free of contaminants-whether chemical, viral, bacterial or microbiological • Environmental and Forensics: From pesticides to pharmaceutical residues to trace metals, Agilent provides fast, accurate and sensitive analytical methods for monitoring contaminants affecting quality of life • Pharmaceutical: Agilent has one of the broadest solutions portfolios of any company serving the pharmaceutical industry • Diagnostics: Agilent's reliable diagnostic products give doctors the information they need in the fight against cancer and other diseases • Chemical and Energy: The world runs on energy, and energy companies need to locate, extract and refine fuels efficiently and cost-effectively • Clinical Research: Most life sciences and clinical research is done at top-tier universities, with funding from governments around the world

QIAGEN N.V., a Netherlands holding company, is the leading global provider of Sample & Assay Technologies that are used to transform biological materials into valuable molecular information. Sample technologies are used to isolate and process DNA, RNA and proteins from biological ... samples such as blood or tissue. Assay technologies are then used to make these isolated biomolecules visible and ready for interpretation. QIAGEN markets more than 500 products around the world, selling both consumable kits and automation systems to customers through four customer classes: Molecular Diagnostics (human healthcare), Applied Testing (forensics, veterinary testing and food safety), Pharma (pharmaceutical and biotechnology companies) and Academia (life sciences research).

Illumina is transforming human health as the global leader in sequencing and array-based technologies. Illumina's flexible and scalable sequencing systems support and enable a wide range of single-cell sequencing applications, from low-throughput deep interrogation of rare cell ... populations to high-throughput profiling of tissues. For more information, please visit www.illumina.com.

Horizon Discovery Group plc, a UK headquartered global life science company, is a world leader in gene editing and gene modulation. Through the application of these technologies the Company enables researchers to alter almost any gene or modulate its function in human or ... mammalian cells to generate models that mimic the genetic abnormalities found in diseases such as cancer. Horizon offers a catalogue of over 1,000,000 cell and reagent products, which along with related research services, support a greater understanding of the function of genes across all species and the genetic drivers of disease, and the development of personalised molecular, cell and gene therapies. These have been adopted by over 10,000 academic, drug discovery, drug manufacturing and clinical diagnostics customers around the globe, and are used in the Company's own R&D pipeline. Horizon is headquartered in Cambridge, UK, and is listed on the London Stock Exchange's AIM market under the ticker "HZD". www.horizondiscovery.com

ATCC is the premier global biological materials resource and standards organization whose mission focuses on the acquisition, authentication, production, preservation, development, and distribution of standard reference microorganisms, cell lines, and other materials. While ... maintaining traditional collection materials, ATCC develops high quality products, standards, and services to support scientific research and breakthroughs that improve the health of global populations.

Cytiva is a global provider of technologies and services that advance and accelerate the development and manufacture of therapeutics. Formerly part of GE Healthcare Life Sciences, we have a rich heritage tracing back hundreds of years, and a fresh beginning since 2020. Our ... customers undertake life-saving activities ranging from fundamental biological research to developing innovative vaccines, biologic drugs, and novel cell and gene therapies. Our job is to supply the tools and services they need to work better, faster and safer, leading to better patient outcomes.

ImmunoChemistry Technologies, LLC provides quality laboratory services and research reagents. As a contract service laboratory, ICT specializes in custom immunoassay development, manufacturing, conjugation, lyophilization, and consulting services. ICT is focused on ELISA ... development and has the knowledge to develop reliable, sensitive, and specific tests. ICT offers a line of ELISA diluents including coat buffers, conjugate stabilizers, and sample diluents designed to reduce backgrounds, increase the specific signal, and improve the stability and shelf-life of the ELISA. ICT also offers a line of fluorescent reagents to measure caspase activity, apoptosis, and cell death in vitro.

Miltenyi Biotec delivers solutions that advance biomedical research and cellular therapy. As the SARS-CoV-2 pandemic continues to take its toll around the world, Miltenyi Biotec stands committed to helping our customers navigate through this challenging time. With over 30 years ... of expertise in immunology and with our dedicated commitment to technological innovation, we offer robust research solutions, cell-specific products, and time- and material-saving tools and protocols that are ideally suited for working with infectious materials.

Canon BioMedical, a wholly owned subsidiary of Canon U.S.A., Inc., is focused on empowering the biomedical research and healthcare communities by developing, manufacturing, and marketing innovative technologies and solutions. The technologies and solutions developed will help ... enable clinicians and scientists to improve our health and advance science. Canon BioMedical will continue to pursue innovative solutions in line with Canon's Kyosei philosophy of social and environmental responsibility through the use of existing and emerging Canon technology as well as strategic partnerships.

BD is a global medical technology company that is advancing the world of health by improving medical discovery, diagnostics and the delivery of care. BD leads in patient and healthcare worker safety and the technologies that enable medical research and clinical laboratories. The ... company provides innovative solutions that help advance medical research and genomics, enhance the diagnosis of infectious disease and cancer, improve medication management, promote infection prevention, equip surgical and interventional procedures and support the management of diabetes.

Qlucore began as a collaborative research project at Lund University, Sweden, with researchers in the Departments of Mathematics and Clinical Genetics. From the beginning, the main problem the project faced was the vast amount of high-dimensional data generated by microarray ... gene expression analysis. As a result, it became clear that an interactive software tool was needed to conceptualize this information. The basic concept behind the Qlucore software is to provide a tool which can take full advantage of the most powerful pattern recognizer that exists - the human brain. The result is a core software engine that visualizes the data in 3D and which can therefore help the user to identify hidden structures and patterns. Over the last five years, a major effort has been made to build upon these early ideas and to develop a core software engine which is extremely fast and allows the user to explore and analyze high-dimensional data sets - interactively and in real time - with the use of a normal PC. Qlucore was founded in early 2007. Since then, a new version of the software has been released approximately every nine months. Qlucore's customers are mainly from the Life Science and Biotech industries.

GenTegra's mission is to protect our customer's samples from harm while in long term storage or while being transported between collection point and the laboratory or biorepository. The Active Chemical Protection™ provided by GenTegra is for weeks, months or decades. Whether ... samples are intended for advanced next generation sequencing or for pre-analytics and in vitro diagnostic our goal is to get the sample to its end use where it can deliver the same results as a freshly collected sample and do this without the need for any cold chain requirement. Reducing the risk of sample loss is an inherent advantage of GenTegra's Active Chemical Protection. Unlike freezing, Active Chemical Protection is not subject to sample loss due to extended power outages. Active Chemical Protection works at ambient temperatures and does not require maintaining freezer banks or even air conditioning for the precious samples to be perfectly safe and secure. Our products, GenTegra-DNA, GenTegra-RNA and GenPlates® allow for ambient transport, as defined by FedEx and UPS with complete protection against measurable damage to the nucleic acids being transported. The same high level of protection is provided for decades of storage at ambient laboratory conditions. If the electrical power is out for weeks there is absolutely no harm to the samples protected by GenTegra's Active Chemical Protection. GenTegra is also actively creating new products, such as our GenSaver™ collection cards, that will provide this same level of protection to pre-analytics samples collected for a variety of in vitro diagnostics tests and health screening applications.

Here's the deal. We're all about helping biologics researchers break free from tools that just don't cut it. Unleashing problem-tackling products that make a huge difference in the real science they do every day. That's our mantra, our promise and we own it.

The combination of Strand and Triesta creates a unique integrated specialized diagnostic company with a focus on next generation precision medicine. With the breadth and depth of our capabilities and expertise, we are confident that we can become a dominant player not only in ... India but also across other geographies.

PacBio® delivers highly accurate long-read sequencing for the most comprehensive view of human genetic variation. Our Sequel® IIe System provides the benefits of HiFi sequencing for deeper biological insights quickly and affordably. PacBio's end-to-end solutions include whole ... genome sequencing for de novo assembly and variant detection, full-length RNA sequencing, and targeted sequencing including our No-Amp approach.

Manuscriptedit specializes in providing services in Scientific & English editing, proofreading, medical writing, academic writing, formatting and publication support. Within a short span of time, the company has grown rapidly to be counted among the world's leading service ... providers in English editing and proofreading. It has served clients in over 80 countries. Manuscriptedit has a healthy blend of over 500 in-house and online contractual editors from top universities and research centres worldwide. The editorial panel includes subject experts in all subject fields of science, medicine, engineering, art, history, economics, politics, humanities, business management and social sciences in addition to English experts.

Bentham Science has three main operating divisions: subscription-based journals, open access titles, and e-books. We publish research literature in all areas of science, medicine, technology, humanities, and social sciences, which is available in both electronic and print ... versions.