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    Engineering T cells

    Engineering T cells is a broad description of techniques used to modify a T cells obtained from a patient or healthy donor. T cells are a subset of immune cells responsible for targeting and killing tumor cells. Once harvested from a patient or donor, the T cells can be engineered in a laboratory making them better capable of killing a specific tumor. Examples of adoptive cell therapies using engineered T cells are T cell receptor (TCR)-engineered T cells and chimeric antigen receptor (CAR) T cells.

    Trending News

    • JUN 01, 2021
      Chemistry & Physics
      "Candy" models allow the visually impaired to visualize complex 3D images with tongue
      "Candy" models allow the visually impaired to visualize complex 3D images with tongue
      New research hopes to improve accessibility to science for people who are blind or visually impaired. Approximately 36 m ...
      Written By: Kathryn DeMuth Sullivan
      2
      MAY 31, 2021
      Immunology
      Engineering Faster, More Agile T Cell Cancer Fighters
      Engineering Faster, More Agile T Cell Cancer Fighters
      Cell therapies use engineered T cells extracted from the patient’s own immune system to rally an attack on tumors. ...
      Written By: Tara Fernandes
      1
      MAY 28, 2021
      Chemistry & Physics
      Are transparent solar cells in our near future?
      Are transparent solar cells in our near future?
      Scientists are searching for alternative technologies to replace traditional silicon solar cells and the limits of their ...
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      MAY 21, 2021
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      New water filtration process mimics our bodies
      New water filtration process mimics our bodies
      An engineering team from The University of Austin has collaborated with international scientists to develop a process th ...
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      2
      MAY 19, 2021
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      How Plant Cell Walls Stay Strong but Flexible
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      MAY 18, 2021
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      Insects, Algae Might be the Way Out of a Future Food Crisis
      It's estimated that two billion people don't have access to reliable sources of nutritious food - they are food insecure ...
      Written By: Carmen Leitch
      1
      MAY 11, 2021
      Genetics & Genomics
      Gene Therapy Trial for Severe Immune Disorder is Successful
      Gene Therapy Trial for Severe Immune Disorder is Successful
      Severe combined immunodeficiency (SCID), which virtually eliminates a patient's immune system, and severely affects thei ...
      Written By: Carmen Leitch
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      MAY 10, 2021
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      Getting RNA-Based Medicine Past the Blood-Brain Barrier
      Getting RNA-Based Medicine Past the Blood-Brain Barrier
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      MAY 05, 2021
      Earth & The Environment
      How much light is too little or too much in a changing climate?
      How much light is too little or too much in a changing climate?
      A simulated evolutionary process in a laboratory has given way to blue-green algae with greater tolerance for high level ...
      Written By: Kathryn DeMuth Sullivan
      2
      MAY 03, 2021
      Microbiology
      A New Bacterial Defense System is Discovered
      A New Bacterial Defense System is Discovered
      Most DNA that we're familiar with is found in cells in a double-stranded form. So, many years ago, scientists were intri ...
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      4
      APR 24, 2021
      Technology
      'Information Theory' Detects Culprit Cancer Genes
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      APR 18, 2021
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      APR 17, 2021
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      Nanofiber-Based Drug Treats Inflammation
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      2
      APR 16, 2021
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      APR 14, 2021
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      APR 05, 2021
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      Introducing DeepTCR, the deep-learning software for T-cell receptor sequencing data
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      Written By: Kathryn DeMuth Sullivan
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      APR 01, 2021
      Immunology
      Tumor-Killing 101: Vaccine Trains Immune Cells to Keep Skin Cancer at Bay
      Tumor-Killing 101: Vaccine Trains Immune Cells to Keep Skin Cancer at Bay
      Cancer researchers have developed a therapeutic vaccine for melanoma, a deadly form of skin cancer. Instead of protectin ...
      Written By: Tara Fernandes
      3
      MAR 26, 2021
      Cell & Molecular Biology
      New 'Bio-ink' Gets 3D-Printed Organs Closer to Reality
      New 'Bio-ink' Gets 3D-Printed Organs Closer to Reality
      For the many people waiting for transplants, 3D-printed organs can't come soon enough. Researchers have been making stri ...
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      MAR 25, 2021
      Microbiology
      Good Microbes Can Help Plants Withstand Heat
      Good Microbes Can Help Plants Withstand Heat
      Bacteria live everywhere, and we're starting to understand how they affect the biology of animals and plants. This comes ...
      Written By: Carmen Leitch
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      MAR 22, 2021
      Immunology
      Gene Mutation Keeps Tumors "Cold"
      Gene Mutation Keeps Tumors "Cold"
      Immunologists have identified a mechanism through which an oncogene mutation shields pancreatic tumors from immune cells ...
      Written By: Tara Fernandes
      2
      MAR 21, 2021
      Cell & Molecular Biology
      A Model of Early Human Development is Created
      A Model of Early Human Development is Created
      Scientists now have a new way to investigate the processes underlying human development, diseases that may arise during ...
      Written By: Carmen Leitch
      1
      MAR 19, 2021
      Cell & Molecular Biology
      These Cells Can Cry Tears
      These Cells Can Cry Tears
      Reporting in Cell Stem Cell, scientists have engineered miniature versions of human tear glands that actually emit tears ...
      Written By: Carmen Leitch
      1
      MAR 18, 2021
      Cancer
      Could electricity impede cancer metastasis?
      Could electricity impede cancer metastasis?
      New research published in the journal Bioelectricity suggests that electricity and electromagnetic fields may deter the ...
      Written By: Kathryn DeMuth Sullivan
      2
    JUN 01, 2021
    Chemistry & Physics
    "Candy" models allow the visually impaired to visualize complex 3D images with tongue
    "Candy" models allow the visually impaired to visualize complex 3D images with tongue
    New research hopes to improve accessibility to science for people who are blind or visually impaired. Approximately 36 m ...
    Written By: Kathryn DeMuth Sullivan
    2
    MAY 31, 2021
    Immunology
    Engineering Faster, More Agile T Cell Cancer Fighters
    Engineering Faster, More Agile T Cell Cancer Fighters
    Cell therapies use engineered T cells extracted from the patient’s own immune system to rally an attack on tumors. ...
    Written By: Tara Fernandes
    1
    MAY 28, 2021
    Chemistry & Physics
    Are transparent solar cells in our near future?
    Are transparent solar cells in our near future?
    Scientists are searching for alternative technologies to replace traditional silicon solar cells and the limits of their ...
    Written By: Kathryn DeMuth Sullivan
    1
    MAY 21, 2021
    Chemistry & Physics
    New water filtration process mimics our bodies
    New water filtration process mimics our bodies
    An engineering team from The University of Austin has collaborated with international scientists to develop a process th ...
    Written By: Kathryn DeMuth Sullivan
    2
    MAY 19, 2021
    Cell & Molecular Biology
    How Plant Cell Walls Stay Strong but Flexible
    How Plant Cell Walls Stay Strong but Flexible
    Plant cell walls have a special ability to expand without breaking or weakening, which is crucial for plant growth. New ...
    Written By: Carmen Leitch
    1
     
     
  • MAY 18, 2021
    Plants & Animals
    Insects, Algae Might be the Way Out of a Future Food Crisis
    Insects, Algae Might be the Way Out of a Future Food Crisis
    It's estimated that two billion people don't have access to reliable sources of nutritious food - they are food insecure ...
    Written By: Carmen Leitch
    1
    MAY 11, 2021
    Genetics & Genomics
    Gene Therapy Trial for Severe Immune Disorder is Successful
    Gene Therapy Trial for Severe Immune Disorder is Successful
    Severe combined immunodeficiency (SCID), which virtually eliminates a patient's immune system, and severely affects thei ...
    Written By: Carmen Leitch
    1
    MAY 10, 2021
    Cell & Molecular Biology
    Getting RNA-Based Medicine Past the Blood-Brain Barrier
    Getting RNA-Based Medicine Past the Blood-Brain Barrier
    RNA molecules serve several functions, one of which is to help the cell generate proteins from active genes. It also may ...
    Written By: Carmen Leitch
    1
    MAY 05, 2021
    Earth & The Environment
    How much light is too little or too much in a changing climate?
    How much light is too little or too much in a changing climate?
    A simulated evolutionary process in a laboratory has given way to blue-green algae with greater tolerance for high level ...
    Written By: Kathryn DeMuth Sullivan
    2
    MAY 03, 2021
    Microbiology
    A New Bacterial Defense System is Discovered
    A New Bacterial Defense System is Discovered
    Most DNA that we're familiar with is found in cells in a double-stranded form. So, many years ago, scientists were intri ...
    Written By: Carmen Leitch
    4
     
     
  • APR 24, 2021
    Technology
    'Information Theory' Detects Culprit Cancer Genes
    'Information Theory' Detects Culprit Cancer Genes
    A team of scientists at Johns Hopkins used “information theory” to uncover key cancer genes. One such culpri ...
    Written By: Nouran Amin
    2
    APR 18, 2021
    Cell & Molecular Biology
    Controlling the Epigenome with CRISPRoff & CRISPRon
    Controlling the Epigenome with CRISPRoff & CRISPRon
    Some parts of the genome are simple; many genes encode for proteins, and if there is an error in one of those protein-co ...
    Written By: Carmen Leitch
    1
    APR 17, 2021
    Drug Discovery & Development
    Nanofiber-Based Drug Treats Inflammation
    Nanofiber-Based Drug Treats Inflammation
    Researchers at Duke University worked on creating a self-assembling nanomaterial-based drug that can help address damage ...
    Written By: Nouran Amin
    2
    APR 16, 2021
    Genetics & Genomics
    Researchers Engineer Human-Monkey Chimera Embryos
    Researchers Engineer Human-Monkey Chimera Embryos
    A chimera human-monkey blastocyst is seen in this image by Weizhi Ji of the Kunming University of Science and Technology ...
    Written By: Carmen Leitch
    1
    APR 14, 2021
    Genetics & Genomics
    The Smell of Home: Insights Into Scent Imprinting
    The Smell of Home: Insights Into Scent Imprinting
    Right after birth, young animals go through a period in which they 'imprint,' or fixate on sights and smells that they'r ...
    Written By: Carmen Leitch
    1
     
     
  • APR 14, 2021
    Chemistry & Physics
    Amping up the fight against superbugs with black phosphorus
    Amping up the fight against superbugs with black phosphorus
    A research team from RMIT University in Melbourne, Australia, has devised an ultra-thin 2D antimicrobial coating that co ...
    Written By: Kathryn DeMuth Sullivan
    3
    APR 05, 2021
    Cancer
    Introducing DeepTCR, the deep-learning software for T-cell receptor sequencing data
    Introducing DeepTCR, the deep-learning software for T-cell receptor sequencing data
    A team from the Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center is introdu ...
    Written By: Kathryn DeMuth Sullivan
    2
    APR 01, 2021
    Immunology
    Tumor-Killing 101: Vaccine Trains Immune Cells to Keep Skin Cancer at Bay
    Tumor-Killing 101: Vaccine Trains Immune Cells to Keep Skin Cancer at Bay
    Cancer researchers have developed a therapeutic vaccine for melanoma, a deadly form of skin cancer. Instead of protectin ...
    Written By: Tara Fernandes
    3
    MAR 26, 2021
    Cell & Molecular Biology
    New 'Bio-ink' Gets 3D-Printed Organs Closer to Reality
    New 'Bio-ink' Gets 3D-Printed Organs Closer to Reality
    For the many people waiting for transplants, 3D-printed organs can't come soon enough. Researchers have been making stri ...
    Written By: Carmen Leitch
    1
    MAR 25, 2021
    Microbiology
    Good Microbes Can Help Plants Withstand Heat
    Good Microbes Can Help Plants Withstand Heat
    Bacteria live everywhere, and we're starting to understand how they affect the biology of animals and plants. This comes ...
    Written By: Carmen Leitch
    1
     
     
  • MAR 22, 2021
    Immunology
    Gene Mutation Keeps Tumors "Cold"
    Gene Mutation Keeps Tumors "Cold"
    Immunologists have identified a mechanism through which an oncogene mutation shields pancreatic tumors from immune cells ...
    Written By: Tara Fernandes
    2
    MAR 21, 2021
    Cell & Molecular Biology
    A Model of Early Human Development is Created
    A Model of Early Human Development is Created
    Scientists now have a new way to investigate the processes underlying human development, diseases that may arise during ...
    Written By: Carmen Leitch
    1
    MAR 19, 2021
    Cell & Molecular Biology
    These Cells Can Cry Tears
    These Cells Can Cry Tears
    Reporting in Cell Stem Cell, scientists have engineered miniature versions of human tear glands that actually emit tears ...
    Written By: Carmen Leitch
    1
    MAR 18, 2021
    Cancer
    Could electricity impede cancer metastasis?
    Could electricity impede cancer metastasis?
    New research published in the journal Bioelectricity suggests that electricity and electromagnetic fields may deter the ...
    Written By: Kathryn DeMuth Sullivan
    2
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