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Gene mutations
Gene mutations describe a change in the DNA sequence that makes up a gene. There are many kinds of gene mutations which have been characterized by scientists. The main categories of mutations are germline mutations, which occur in the gametes (haploid male or female reproductive cells), and somatic mutations, occur in all other cell types. Chromosomal alterations are mutations that change the structure of chromosomes in a variety of ways such as deletion, duplication, insertion, translocation, or inversion of a section of the chromosome. Point mutations include a single nucleotide change within the DNA and these mutations can be classified as silent (the mutation codes for the same amino acid so the change has no effect), missense (the mutation codes for an alternative amino acid), and nonsense (the mutation codes for a premature stop codon). Frameshift mutations occur when the addition or deletion of nucleotide(s) alter the reading frame of the sequence altering all subsequent amino acid coding.
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DEC 21, 2020Cell & Molecular Biology
New research has suggested that our DNA is more susceptible to mutagenic influences than we've appreciated. While organi ...Written By: Carmen LeitchDEC 21, 2020Genetics & Genomics
Salmonella are human & animal bacterial pathogens that are found everywhere. When the bacterium infects a person, it cau ...Written By: Carmen LeitchDEC 20, 2020Drug Discovery & Development
A fungal-targeting drug was shown to improve symptoms of cystic fibrosis particularly key biomarkers in lung tissue cult ...Written By: Nouran AminDEC 20, 2020Genetics & Genomics
Some researchers have sought to treat genetic diseases by correcting the mutation. But it may be possible to use another ...Written By: Carmen LeitchDEC 16, 2020Clinical & Molecular DX
In cervical cancer, mutations in healthy cells cause cells to grow and multiply uncontrollably, invading surrounding tis ...Written By: Tara FernandesDEC 15, 2020Cancer
New research from scientists at the UCLA Jonsson Comprehensive Cancer Center showcases a novel combination therapy that ...Written By: Kathryn DeMuth SullivanDEC 14, 2020Cell & Molecular Biology
Max Planck Institute for Molecular Genetics researchers have created a model that will advance the study of development ...Written By: Carmen LeitchDEC 13, 2020Cardiology
The most common cause of heart disease in elderly people is calcific aortic valve disease, in which calcium builds up in ...Written By: Carmen LeitchDEC 08, 2020Genetics & Genomics
The many advances that have propelled the field of genetics forward have taken a tremendous amount of work in different ...Written By: Carmen LeitchDEC 04, 2020Genetics & Genomics
The CRISPR-Cas9 gene-editing tool has tremendous potential to treat genetic diseases, but sometimes it makes unintended ...Written By: Carmen LeitchDEC 03, 2020Cancer
New research published in Cancer Discovery highlights the increased presence of genetic mutations in Latin American lung ...Written By: Kathryn DeMuth SullivanNOV 29, 2020Genetics & Genomics
In recent years, scientists have been able to develop gene therapies to treat some eye diseases. The eyes are uniquely q ...Written By: Carmen LeitchNOV 27, 2020Cell & Molecular Biology
The sun emits different kinds of light and rays including visible and ultraviolet (UV) and infrared. Some of those forms ...Written By: Carmen LeitchNOV 23, 2020Genetics & Genomics
Clinicians have identified a patient with a rare inherited disorder that disrupts the production of fresh blood cells, a ...Written By: Carmen LeitchNOV 23, 2020Microbiology
The pathogenic bacterium that causes tuberculosis, Mycobacterium tuberculosis, does not multiply quickly, so researchers ...Written By: Carmen LeitchNOV 22, 2020Genetics & Genomics
Our bodies need cholesterol for certain crucial functions; it's a vital component of cell walls, for example. But there ...Written By: Carmen LeitchNOV 20, 2020Genetics & Genomics
Genetic mutations are usually connected to disease, but there are some that are known to improve people's lives.Written By: Carmen LeitchNOV 18, 2020Genetics & Genomics
It’s easy to be overwhelmed by the number of workflows that are available for NGS. How do you choose? While ...Sponsored By: Roche DiagnosticsNOV 17, 2020Genetics & Genomics
A large family with some members that have a rare brain disorder has helped scientists learn more about both brain devel ...Written By: Carmen LeitchNOV 16, 2020Genetics & Genomics
It's essential for organisms to use their genomes to make proteins, and the processes of transcription and translation a ...Written By: Carmen LeitchNOV 15, 2020Genetics & Genomics
Cells have to be able to divide so new ones can replenish cells that get worn out, dysfunctional, or that accumulate dam ...Written By: Carmen LeitchNOV 12, 2020Cardiology
Cardiovascular disease is something that, in most cases, is within our ability to control. A healthy diet and active lif ...Written By: Jasper CantrellNOV 11, 2020Cell & Molecular Biology
Many types of cells in our bodies are short-lived and need to be replenished. Cell division has to be carefully controll ...Written By: Carmen LeitchNOV 09, 2020Genetics & Genomics
Liquid biopsies are tests that look for biomarkers in the blood, which can help inform the treatment of cancer. The tool ...Written By: Carmen Leitch
DEC 21, 2020
Cell & Molecular Biology
New research has suggested that our DNA is more susceptible to mutagenic influences than we've appreciated. While organi
...
Written By:
Carmen Leitch
DEC 21, 2020
Genetics & Genomics
Salmonella are human & animal bacterial pathogens that are found everywhere. When the bacterium infects a person, it cau
...
Written By:
Carmen Leitch
DEC 20, 2020
Drug Discovery & Development
A fungal-targeting drug was shown to improve symptoms of cystic fibrosis particularly key biomarkers in lung tissue cult
...
Written By:
Nouran Amin
DEC 20, 2020
Genetics & Genomics
Some researchers have sought to treat genetic diseases by correcting the mutation. But it may be possible to use another
...
Written By:
Carmen Leitch
DEC 16, 2020
Clinical & Molecular DX
In cervical cancer, mutations in healthy cells cause cells to grow and multiply uncontrollably, invading surrounding tis
...
Written By:
Tara Fernandes
DEC 15, 2020
Cancer
New research from scientists at the UCLA Jonsson Comprehensive Cancer Center showcases a novel combination therapy that
...
Written By:
Kathryn DeMuth Sullivan
DEC 14, 2020
Cell & Molecular Biology
Max Planck Institute for Molecular Genetics researchers have created a model that will advance the study of development
...
Written By:
Carmen Leitch
DEC 13, 2020
Cardiology
The most common cause of heart disease in elderly people is calcific aortic valve disease, in which calcium builds up in
...
Written By:
Carmen Leitch
DEC 08, 2020
Genetics & Genomics
The many advances that have propelled the field of genetics forward have taken a tremendous amount of work in different
...
Written By:
Carmen Leitch
DEC 04, 2020
Genetics & Genomics
The CRISPR-Cas9 gene-editing tool has tremendous potential to treat genetic diseases, but sometimes it makes unintended
...
Written By:
Carmen Leitch
DEC 03, 2020
Cancer
New research published in Cancer Discovery highlights the increased presence of genetic mutations in Latin American lung
...
Written By:
Kathryn DeMuth Sullivan
NOV 29, 2020
Genetics & Genomics
In recent years, scientists have been able to develop gene therapies to treat some eye diseases. The eyes are uniquely q
...
Written By:
Carmen Leitch
NOV 27, 2020
Cell & Molecular Biology
The sun emits different kinds of light and rays including visible and ultraviolet (UV) and infrared. Some of those forms
...
Written By:
Carmen Leitch
NOV 23, 2020
Genetics & Genomics
Clinicians have identified a patient with a rare inherited disorder that disrupts the production of fresh blood cells, a
...
Written By:
Carmen Leitch
NOV 23, 2020
Microbiology
The pathogenic bacterium that causes tuberculosis, Mycobacterium tuberculosis, does not multiply quickly, so researchers
...
Written By:
Carmen Leitch
NOV 22, 2020
Genetics & Genomics
Our bodies need cholesterol for certain crucial functions; it's a vital component of cell walls, for example. But there
...
Written By:
Carmen Leitch
NOV 20, 2020
Genetics & Genomics
Genetic mutations are usually connected to disease, but there are some that are known to improve people's lives.
Written By:
Carmen Leitch
NOV 18, 2020
Genetics & Genomics
It’s easy to be overwhelmed by the number of workflows that are available for NGS. How do you choose? While
...
Sponsored By:
Roche Diagnostics
NOV 17, 2020
Genetics & Genomics
A large family with some members that have a rare brain disorder has helped scientists learn more about both brain devel
...
Written By:
Carmen Leitch
NOV 16, 2020
Genetics & Genomics
It's essential for organisms to use their genomes to make proteins, and the processes of transcription and translation a
...
Written By:
Carmen Leitch
NOV 15, 2020
Genetics & Genomics
Cells have to be able to divide so new ones can replenish cells that get worn out, dysfunctional, or that accumulate dam
...
Written By:
Carmen Leitch
NOV 12, 2020
Cardiology
Cardiovascular disease is something that, in most cases, is within our ability to control. A healthy diet and active lif
...
Written By:
Jasper Cantrell
NOV 11, 2020
Cell & Molecular Biology
Many types of cells in our bodies are short-lived and need to be replenished. Cell division has to be carefully controll
...
Written By:
Carmen Leitch
NOV 09, 2020
Genetics & Genomics
Liquid biopsies are tests that look for biomarkers in the blood, which can help inform the treatment of cancer. The tool
...
Written By:
Carmen Leitch