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Gene mutations
Gene mutations describe a change in the DNA sequence that makes up a gene. There are many kinds of gene mutations which have been characterized by scientists. The main categories of mutations are germline mutations, which occur in the gametes (haploid male or female reproductive cells), and somatic mutations, occur in all other cell types. Chromosomal alterations are mutations that change the structure of chromosomes in a variety of ways such as deletion, duplication, insertion, translocation, or inversion of a section of the chromosome. Point mutations include a single nucleotide change within the DNA and these mutations can be classified as silent (the mutation codes for the same amino acid so the change has no effect), missense (the mutation codes for an alternative amino acid), and nonsense (the mutation codes for a premature stop codon). Frameshift mutations occur when the addition or deletion of nucleotide(s) alter the reading frame of the sequence altering all subsequent amino acid coding.
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JUN 18, 2015Cancer
According to the National Cancer Institute, prostate cancer is the most common cancer in men in the United States, after ...Written By: Ilene SchneiderJUN 14, 2015Cancer
Oligodendroglioma, which can be an especially aggressive form of brain cancer, may be caused by a genetic mutation. Scie ...Written By: Ilene SchneiderJUN 05, 2015Videos
Space madness-the term NASA originally coined to describe a psychotic episode it worried would beset one of its astronau ...Written By: Will HectorMAY 21, 2015Cancer
When people reach late middle age, about a quarter of their skin cells carry cancer-driving mutations caused by exposure ...Written By: Ilene SchneiderMAY 15, 2015Cancer
While osteosarcoma, the most common type of cancer that starts in the bone, is rare, the consequences can be devastating ...Written By: Ilene SchneiderMAY 01, 2015Genetics & Genomics
Chemotherapy drugs damage DNA, keeping cells from replicating. However, according to researchers at the UNC School of Me ...Written By: Ilene SchneiderAPR 29, 2015Chemistry & Physics
What to do when a patient needs a blood transfusion but you don't have their blood type in the blood bank? It's a proble ...Written By: Judy O'RourkeAPR 28, 2015Genetics & Genomics
Researchers at the Institut de Recherches Cliniques de Montreal (IRCM) led by Artur Kania, Ph.D., uncovered the critical ...Written By: Ilene SchneiderAPR 28, 2015Genetics & Genomics
Yale researchers successfully corrected the most common mutation in the gene that causes cystic fibrosis, a lethal genet ...Written By: Ilene SchneiderAPR 28, 2015Genetics & Genomics
Scientists from Johns Hopkins have found that neurons are not risk-averse, if fact, they use minor "DNA surgeries" to to ...Written By: Judy O'RourkeAPR 27, 2015Genetics & Genomics
Our genomes are riddled with the detritus of ancient viruses. They infected our hominid ancestors tens of millions of ye ...Written By: Robert WoodardAPR 27, 2015Genetics & Genomics
EPFL scientists discover that certain cell structures, the centrioles, could act as information carriers throughout cell ...Written By: Will HectorAPR 23, 2015Genetics & Genomics
In light of recent developments, New York Times columnist Carl Zimmer offered this perspective on National Geographic's ...Written By: Robert WoodardAPR 23, 2015Cancer
Men with prostate cancer benefit from treatment with the pioneering drug olaparib - the first cancer drug to target inhe ...Written By: Ilene SchneiderAPR 22, 2015Genetics & Genomics
Could the epigenome provide a new avenue for gene therapies and guiding stem cell differentiation?
Written By: Robert WoodardAPR 22, 2015Genetics & Genomics
Researchers have uncovered the first evidence of a genetic link between prodigy and autism.
The scientists fo ...Written By: Judy O'RourkeAPR 22, 2015Cancer
A new research study has shown that pancreatic cancer cells can be coaxed to revert back toward normal cells by introduc ...Written By: Ilene SchneiderAPR 21, 2015Genetics & Genomics
Using the latest genome sequencing techniques, a research team led by scientists from UC San Francisco, Baylor College o ...Written By: Ilene SchneiderAPR 19, 2015Genetics & Genomics
Aneuploidy-the incorrect number of chromosomes in a cell-is quite common in early embryos; it's also the primary reason ...Written By: Will HectorAPR 17, 2015Cancer
The first-ever systematic study of the genomes of patients with ALK-negative anaplastic large cell lymphoma (ALCL), a pa ...Written By: Ilene SchneiderAPR 16, 2015Cancer
When it comes to sequencing patients' tumor genomes to personalize cancer therapy, one very important step may be missin ...Written By: Ilene SchneiderAPR 15, 2015Genetics & Genomics
An international research project to sequence whole genomes from mountain gorillas has given scientists and conservation ...Written By: Ilene SchneiderAPR 15, 2015Genetics & Genomics
Maintaining the stability and the correct sequence of our genetic information is vital to the accurate transmission of o ...Written By: Robert WoodardAPR 13, 2015Microbiology
," he says.
And it's not always possible to breast-feed, while some women choose not to. That's one reason wh ...Written By: Robert Woodard
JUN 18, 2015
Cancer
According to the National Cancer Institute, prostate cancer is the most common cancer in men in the United States, after
...
Written By:
Ilene Schneider
JUN 14, 2015
Cancer
Oligodendroglioma, which can be an especially aggressive form of brain cancer, may be caused by a genetic mutation. Scie
...
Written By:
Ilene Schneider
JUN 05, 2015
Videos
Space madness-the term NASA originally coined to describe a psychotic episode it worried would beset one of its astronau
...
Written By:
Will Hector
MAY 21, 2015
Cancer
When people reach late middle age, about a quarter of their skin cells carry cancer-driving mutations caused by exposure
...
Written By:
Ilene Schneider
MAY 15, 2015
Cancer
While osteosarcoma, the most common type of cancer that starts in the bone, is rare, the consequences can be devastating
...
Written By:
Ilene Schneider
MAY 01, 2015
Genetics & Genomics
Chemotherapy drugs damage DNA, keeping cells from replicating. However, according to researchers at the UNC School of Me
...
Written By:
Ilene Schneider
APR 29, 2015
Chemistry & Physics
What to do when a patient needs a blood transfusion but you don't have their blood type in the blood bank? It's a proble
...
Written By:
Judy O'Rourke
APR 28, 2015
Genetics & Genomics
Researchers at the Institut de Recherches Cliniques de Montreal (IRCM) led by Artur Kania, Ph.D., uncovered the critical
...
Written By:
Ilene Schneider
APR 28, 2015
Genetics & Genomics
Yale researchers successfully corrected the most common mutation in the gene that causes cystic fibrosis, a lethal genet
...
Written By:
Ilene Schneider
APR 28, 2015
Genetics & Genomics
Scientists from Johns Hopkins have found that neurons are not risk-averse, if fact, they use minor "DNA surgeries" to to
...
Written By:
Judy O'Rourke
APR 27, 2015
Genetics & Genomics
Our genomes are riddled with the detritus of ancient viruses. They infected our hominid ancestors tens of millions of ye
...
Written By:
Robert Woodard
APR 27, 2015
Genetics & Genomics
EPFL scientists discover that certain cell structures, the centrioles, could act as information carriers throughout cell
...
Written By:
Will Hector
APR 23, 2015
Genetics & Genomics
In light of recent developments, New York Times columnist Carl Zimmer offered this perspective on National Geographic's
...
Written By:
Robert Woodard
APR 23, 2015
Cancer
Men with prostate cancer benefit from treatment with the pioneering drug olaparib - the first cancer drug to target inhe
...
Written By:
Ilene Schneider
APR 22, 2015
Genetics & Genomics
Could the epigenome provide a new avenue for gene therapies and guiding stem cell differentiation?
Written By:
Robert Woodard
APR 22, 2015
Genetics & Genomics
Researchers have uncovered the first evidence of a genetic link between prodigy and autism.
The scientists fo ...
The scientists fo ...
Written By:
Judy O'Rourke
APR 22, 2015
Cancer
A new research study has shown that pancreatic cancer cells can be coaxed to revert back toward normal cells by introduc
...
Written By:
Ilene Schneider
APR 21, 2015
Genetics & Genomics
Using the latest genome sequencing techniques, a research team led by scientists from UC San Francisco, Baylor College o
...
Written By:
Ilene Schneider
APR 19, 2015
Genetics & Genomics
Aneuploidy-the incorrect number of chromosomes in a cell-is quite common in early embryos; it's also the primary reason
...
Written By:
Will Hector
APR 17, 2015
Cancer
The first-ever systematic study of the genomes of patients with ALK-negative anaplastic large cell lymphoma (ALCL), a pa
...
Written By:
Ilene Schneider
APR 16, 2015
Cancer
When it comes to sequencing patients' tumor genomes to personalize cancer therapy, one very important step may be missin
...
Written By:
Ilene Schneider
APR 15, 2015
Genetics & Genomics
An international research project to sequence whole genomes from mountain gorillas has given scientists and conservation
...
Written By:
Ilene Schneider
APR 15, 2015
Genetics & Genomics
Maintaining the stability and the correct sequence of our genetic information is vital to the accurate transmission of o
...
Written By:
Robert Woodard
APR 13, 2015
Microbiology
," he says.
And it's not always possible to breast-feed, while some women choose not to. That's one reason wh ...
And it's not always possible to breast-feed, while some women choose not to. That's one reason wh ...
Written By:
Robert Woodard