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Gene mutations
Gene mutations describe a change in the DNA sequence that makes up a gene. There are many kinds of gene mutations which have been characterized by scientists. The main categories of mutations are germline mutations, which occur in the gametes (haploid male or female reproductive cells), and somatic mutations, occur in all other cell types. Chromosomal alterations are mutations that change the structure of chromosomes in a variety of ways such as deletion, duplication, insertion, translocation, or inversion of a section of the chromosome. Point mutations include a single nucleotide change within the DNA and these mutations can be classified as silent (the mutation codes for the same amino acid so the change has no effect), missense (the mutation codes for an alternative amino acid), and nonsense (the mutation codes for a premature stop codon). Frameshift mutations occur when the addition or deletion of nucleotide(s) alter the reading frame of the sequence altering all subsequent amino acid coding.
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MAR 16, 2015Cancer
In the late 1800s, a New York surgeon named William Coley noticed that some patients with cancer seemed to fare better i ...Written By: Ilene SchneiderMAR 13, 2015Cardiology
To find out how blood flow in the heart shields against the hardening of valves in cardiovascular disease, researchers u ...Written By: Judy O'RourkeMAR 12, 2015Genetics & Genomics
A new study reveals an important connection between dozens of genes that may contribute to autism, a major step toward u ...Written By: Ilene SchneiderMAR 12, 2015Genetics & Genomics
A team of researchers has sequenced the genome of classical Hodgkin lymphoma, illuminating exactly which proteins are al ...Written By: Ilene SchneiderMAR 10, 2015Genetics & Genomics
In an advance that could lead to better identification of malignant pediatric adrenocortical tumors, and ultimately to b ...Written By: Ilene SchneiderMAR 09, 2015Genetics & Genomics
UCLA stem cell researchers have shown that a novel stem cell gene therapy method could lead to a one-time, lasting treat ...Written By: Ilene SchneiderMAR 09, 2015Genetics & Genomics
A first-of-its-kind study shows that who we inherit genetic variants from - our mother or father - is crucial for the de ...Written By: Judy O'RourkeMAR 06, 2015Neuroscience
If you walk into your local drug store and ask for a supplement to help you sleep, you might be directed to a bottle lab ...Written By: Ilene SchneiderMAR 05, 2015Neuroscience
A study from Harvard Medical School researchers at Massachusetts General Hospital and Brigham and Women's Hospital revea ...Written By: Ilene SchneiderFEB 27, 2015Genetics & Genomics
Genetically engineered T memory stem cells (Tscm) can last more than 12 years in patients' bodies, and can continually g ...Written By: Ilene SchneiderFEB 27, 2015Microbiology
Researchers at the University of York, UK, are part of a team of scientists that has discovered how bacteria can restart ...Written By: Judy O'RourkeFEB 25, 2015Cancer
In greater than 90 percent of cases in which treatment for metastatic cancer fails, the reason is that the cancer is res ...Written By: Ilene SchneiderFEB 23, 2015Genetics & Genomics
The FDA has approved the Bloom Syndrome carrier test from 23andMe, Mountain View, Calif, a direct-to-consumer (DTC) gene ...Written By: Judy O'RourkeFEB 16, 2015Health & Medicine
While it has long been known that obesity can negatively affect health in terms of cardiovascular disease, diabetes and ...Written By: Brenda Kelley KimJAN 06, 2015Earth & The Environment
Our planet's population is growing rapidly, perhaps too rapidly for our natural resources. Experts estimate that by the ...Written By: Brenda Kelley KimJAN 05, 2015Immunology
While our immune system counts on the production of antibodies to spot and sap bacteria and viruses, it does not stockpi ...Written By: Judy O'RourkeDEC 24, 2014Genetics & Genomics
Premature ovarian failure, also known as primary ovarian insufficiency (POI), affects 1 percent of all women worldwide. ...Written By: Ilene SchneiderDEC 04, 2014Cancer
Cancer researchers aiming to gain new insights into the disease are looking at it from a new angle. Through the prism of ...Written By: Judy O'RourkeDEC 02, 2014Genetics & Genomics
Two different research teams affiliated with the Broad Institute at Harvard and MIT have come up with startlingly simila ...Written By: Brenda Kelley KimNOV 18, 2014Cancer
Olaparib, an experimental twice-daily oral cancer drug, produces an overall tumor response rate of 26 percent in several ...Written By: Ilene SchneiderNOV 17, 2014Videos
A new study finds a gene mutation may protect people from high levels of bad cholesterol and heart disease, and could be ...Written By: Judy O'RourkeOCT 22, 2014Cell & Molecular Biology
How and how much living things are affected by nature vs. nurture has been an ongoing debate for many years. But, the wh ...Written By: Peter Micheli
MAR 16, 2015
Cancer
In the late 1800s, a New York surgeon named William Coley noticed that some patients with cancer seemed to fare better i
...
Written By:
Ilene Schneider
MAR 13, 2015
Cardiology
To find out how blood flow in the heart shields against the hardening of valves in cardiovascular disease, researchers u
...
Written By:
Judy O'Rourke
MAR 12, 2015
Genetics & Genomics
A new study reveals an important connection between dozens of genes that may contribute to autism, a major step toward u
...
Written By:
Ilene Schneider
MAR 12, 2015
Genetics & Genomics
A team of researchers has sequenced the genome of classical Hodgkin lymphoma, illuminating exactly which proteins are al
...
Written By:
Ilene Schneider
MAR 10, 2015
Genetics & Genomics
In an advance that could lead to better identification of malignant pediatric adrenocortical tumors, and ultimately to b
...
Written By:
Ilene Schneider
MAR 09, 2015
Genetics & Genomics
UCLA stem cell researchers have shown that a novel stem cell gene therapy method could lead to a one-time, lasting treat
...
Written By:
Ilene Schneider
MAR 09, 2015
Genetics & Genomics
A first-of-its-kind study shows that who we inherit genetic variants from - our mother or father - is crucial for the de
...
Written By:
Judy O'Rourke
MAR 06, 2015
Neuroscience
If you walk into your local drug store and ask for a supplement to help you sleep, you might be directed to a bottle lab
...
Written By:
Ilene Schneider
MAR 05, 2015
Neuroscience
A study from Harvard Medical School researchers at Massachusetts General Hospital and Brigham and Women's Hospital revea
...
Written By:
Ilene Schneider
FEB 27, 2015
Genetics & Genomics
Genetically engineered T memory stem cells (Tscm) can last more than 12 years in patients' bodies, and can continually g
...
Written By:
Ilene Schneider
FEB 27, 2015
Microbiology
Researchers at the University of York, UK, are part of a team of scientists that has discovered how bacteria can restart
...
Written By:
Judy O'Rourke
FEB 25, 2015
Cancer
In greater than 90 percent of cases in which treatment for metastatic cancer fails, the reason is that the cancer is res
...
Written By:
Ilene Schneider
FEB 23, 2015
Genetics & Genomics
The FDA has approved the Bloom Syndrome carrier test from 23andMe, Mountain View, Calif, a direct-to-consumer (DTC) gene
...
Written By:
Judy O'Rourke
FEB 16, 2015
Health & Medicine
While it has long been known that obesity can negatively affect health in terms of cardiovascular disease, diabetes and
...
Written By:
Brenda Kelley Kim
JAN 06, 2015
Earth & The Environment
Our planet's population is growing rapidly, perhaps too rapidly for our natural resources. Experts estimate that by the
...
Written By:
Brenda Kelley Kim
JAN 05, 2015
Immunology
While our immune system counts on the production of antibodies to spot and sap bacteria and viruses, it does not stockpi
...
Written By:
Judy O'Rourke
DEC 24, 2014
Genetics & Genomics
Premature ovarian failure, also known as primary ovarian insufficiency (POI), affects 1 percent of all women worldwide.
...
Written By:
Ilene Schneider
DEC 04, 2014
Cancer
Cancer researchers aiming to gain new insights into the disease are looking at it from a new angle. Through the prism of
...
Written By:
Judy O'Rourke
DEC 02, 2014
Genetics & Genomics
Two different research teams affiliated with the Broad Institute at Harvard and MIT have come up with startlingly simila
...
Written By:
Brenda Kelley Kim
NOV 18, 2014
Cancer
Olaparib, an experimental twice-daily oral cancer drug, produces an overall tumor response rate of 26 percent in several
...
Written By:
Ilene Schneider
NOV 17, 2014
Videos
A new study finds a gene mutation may protect people from high levels of bad cholesterol and heart disease, and could be
...
Written By:
Judy O'Rourke
OCT 22, 2014
Cell & Molecular Biology
How and how much living things are affected by nature vs. nurture has been an ongoing debate for many years. But, the wh
...
Written By:
Peter Micheli