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Oligo Synthesis
Oligo Synthesis: Oligonucleotide synthesis is the chemical synthesis of relatively short fragments of nucleic acids with defined chemical structure (sequence). The technique is extremely useful in current laboratory practice because it provides a rapid and inexpensive access to custom-made oligonucleotides of the desired sequence. Whereas enzymes synthesize DNA and RNA only in a 5' to 3' direction, chemical oligonucleotide synthesis does not have this limitation, although it is, most often, carried out in the opposite, 3' to 5' direction. Currently, the process is implemented as solid-phase synthesis using phosphoramidite method and phosphoramidite building blocks derived from protected 2'-deoxynucleosides (dA, dC, dG, and T), ribonucleosides (A, C, G, and U), or chemically modified nucleosides, e.g. LNA or BNA.
What's Popular in Oligo Synthesis
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MAY 18, 2021Genetics & Genomics
As the SARS-CoV-2 virus continues to mutate, rapid sequencing of COVID-19-positive samples is more critical than ever. N ...Sponsored By: Roche DiagnosticsOCT 30, 2018Drug Discovery & Development
Understanding how cancer cells avoid death despite their DNA being damaged will create new strategies to enhance cancer ...Written By: Nouran Amin
MAY 18, 2021
Genetics & Genomics
As the SARS-CoV-2 virus continues to mutate, rapid sequencing of COVID-19-positive samples is more critical than ever. N
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Sponsored By:
Roche Diagnostics
OCT 30, 2018
Drug Discovery & Development
Understanding how cancer cells avoid death despite their DNA being damaged will create new strategies to enhance cancer
...
Written By:
Nouran Amin
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SEP 27, 2022 | 9:00 AM
Date: September 27, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Synthetic DNA oligonucleotides are used broadly across many different application areas, from basic R&D to clini...MAR 29, 2022 | 9:00 AMC.E. CREDITS
Date: March 29, 2022 Time: 09:00am (PDT), 12:00pm (EDT), 17:00 (GMT) Advances in molecular and immunodiagnostics are enabling a personalized, high-precision approach to health in many clin...SEP 14, 2021 | 7:00 AM
Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...MAY 25, 2021 | 8:00 AM
Date: May 25, 2021 Time: 8:00am (PDT) Reliable expression of recombinant proteins in human, CHO, or insect cells is essential for many aspects of biomedical research and drug development, bu...MAY 11, 2021 | 10:00 AM
Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...Speaker: Paulina Kocjan , Kate Meola , Zareh Zurabyan
SEP 27, 2022 | 9:00 AM
Date: September 27, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Synthetic DNA oligonucleotides are used broadly across many different application areas, from basic R&D to clini...
MAR 29, 2022 | 9:00 AM
C.E. CREDITS
Date: March 29, 2022 Time: 09:00am (PDT), 12:00pm (EDT), 17:00 (GMT) Advances in molecular and immunodiagnostics are enabling a personalized, high-precision approach to health in many clin...
SEP 14, 2021 | 7:00 AM
Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...
MAY 25, 2021 | 8:00 AM
Date: May 25, 2021 Time: 8:00am (PDT) Reliable expression of recombinant proteins in human, CHO, or insect cells is essential for many aspects of biomedical research and drug development, bu...
MAY 11, 2021 | 10:00 AM
Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
Speaker:
Paulina Kocjan
, Kate Meola
, Zareh Zurabyan
FEB 24, 2021 | 10:00 AM
DATE: February 24, 2021 TIME: 10am PST Automated lab instruments such as liquid handlers and cell sorters are increasingly common in all types of laboratories, driving fast results for labor...
DEC 02, 2020 | 8:00 AM
DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
SEP 30, 2020 | 6:00 AM
Genome editing with an expanded CRISPR-Cas tool set increases the opportunity to make intentional, targeted changes in the genome. Furthermore, improved specificity of genome editing and abi...
JUL 22, 2020 | 10:00 AM
DATE: July 23, 2020 TIME: 10:00 am PDT The SARS-CoV-2 pandemic has taken a toll on many sectors of the medical community. As the pandemic took a grip on the laboratory, the need for diagnost...
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NOV 10, 2020
Please join us for this FREE workshop, as we present Agilent’s LC/MS hardware and software solutions for getting the most out of your analysis data....MAY 10, 2017 | 6:00 AM PDTC.E. CREDITS
The 5th Annual Event in the Genetics and Genomics Virtual Event Series is now On Demand. This event covers the most recent and exciting advances in genetics research....
NOV 10, 2020
Please join us for this FREE workshop, as we present Agilent’s LC/MS hardware and software solutions for getting the most out of your analysis data....
MAY 10, 2017
| 6:00 AM PDT
C.E. CREDITS
The 5th Annual Event in the Genetics and Genomics Virtual Event Series is now On Demand. This event covers the most recent and exciting advances in genetics research....