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    Oligo Synthesis

    Oligo Synthesis: Oligonucleotide synthesis is the chemical synthesis of relatively short fragments of nucleic acids with defined chemical structure (sequence). The technique is extremely useful in current laboratory practice because it provides a rapid and inexpensive access to custom-made oligonucleotides of the desired sequence. Whereas enzymes synthesize DNA and RNA only in a 5' to 3' direction, chemical oligonucleotide synthesis does not have this limitation, although it is, most often, carried out in the opposite, 3' to 5' direction. Currently, the process is implemented as solid-phase synthesis using phosphoramidite method and phosphoramidite building blocks derived from protected 2'-deoxynucleosides (dA, dC, dG, and T), ribonucleosides (A, C, G, and U), or chemically modified nucleosides, e.g. LNA or BNA.

    What's Popular in Oligo Synthesis

    Trending News

    • MAY 18, 2021
      Genetics & Genomics
      Library Prep Methods for SARS-CoV-2 Sequencing: a Summary
      Library Prep Methods for SARS-CoV-2 Sequencing: a Summary
      As the SARS-CoV-2 virus continues to mutate, rapid sequencing of COVID-19-positive samples is more critical than ever. N ...
      Sponsored By: Roche Diagnostics
      2
      OCT 30, 2018
      Drug Discovery & Development
      Re-sensitizing Drug-resistant Human Tumor Cells
      Re-sensitizing Drug-resistant Human Tumor Cells
      Understanding how cancer cells avoid death despite their DNA being damaged will create new strategies to enhance cancer ...
      Written By: Nouran Amin
      2
    MAY 18, 2021
    Genetics & Genomics
    Library Prep Methods for SARS-CoV-2 Sequencing: a Summary
    Library Prep Methods for SARS-CoV-2 Sequencing: a Summary
    As the SARS-CoV-2 virus continues to mutate, rapid sequencing of COVID-19-positive samples is more critical than ever. N ...
    Sponsored By: Roche Diagnostics
    2
    OCT 30, 2018
    Drug Discovery & Development
    Re-sensitizing Drug-resistant Human Tumor Cells
    Re-sensitizing Drug-resistant Human Tumor Cells
    Understanding how cancer cells avoid death despite their DNA being damaged will create new strategies to enhance cancer ...
    Written By: Nouran Amin
    2

    Webinars

    • SEP 27, 2022 | 9:00 AM
      Evolution of scale for synthetic oligos
      Evolution of scale for synthetic oligos
      Date: September 27, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Synthetic DNA oligonucleotides are used broadly across many different application areas, from basic R&D to clini...
      Speaker: Ben Hinton, BSc
      Sponsored By: Thermo Fisher Scientific
      12
      MAR 29, 2022 | 9:00 AM
      Accelerating commercialization with custom OEM solutions and GMP
      Accelerating commercialization with custom OEM solutions and GMP
      Date: March 29, 2022 Time: 09:00am (PDT), 12:00pm (EDT), 17:00 (GMT) Advances in molecular and immunodiagnostics are enabling a personalized, high-precision approach to health in many clin...
      Speaker: Matthew Davies , Amy Webster , Mitch Gore , Renee Rathjen
      Sponsored By: Cytiva, IDT
      5
      SEP 14, 2021 | 7:00 AM
      What prevents you from increasing your PCR productivity?
      What prevents you from increasing your PCR productivity?
      Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...
      Speaker: Arora Phang, PhD
      Sponsored By: Eppendorf
      24 1
      MAY 25, 2021 | 8:00 AM
      Complete Workflow Solution from Gene-to-Protein
      Complete Workflow Solution from Gene-to-Protein
      Date: May 25, 2021 Time: 8:00am (PDT) Reliable expression of recombinant proteins in human, CHO, or insect cells is essential for many aspects of biomedical research and drug development, bu...
      Speaker: Stephan Fath, PhD
      Sponsored By: Thermo Fisher Scientific
      16 1
      MAY 11, 2021 | 10:00 AM
      Secure Your Next Great Discovery
      Secure Your Next Great Discovery
      Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
      Speaker: Paulina Kocjan , Kate Meola , Zareh Zurabyan
      Presented at: Eppendorf Planet of Knowledge - A New Dimension
      Sponsored By: Eppendorf
      8
    SEP 27, 2022 | 9:00 AM
    Evolution of scale for synthetic oligos
    Evolution of scale for synthetic oligos
    Date: September 27, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Synthetic DNA oligonucleotides are used broadly across many different application areas, from basic R&D to clini...
    Speaker: Ben Hinton, BSc
    Sponsored By: Thermo Fisher Scientific
    12
    MAR 29, 2022 | 9:00 AM
    Accelerating commercialization with custom OEM solutions and GMP
    Accelerating commercialization with custom OEM solutions and GMP
    Date: March 29, 2022 Time: 09:00am (PDT), 12:00pm (EDT), 17:00 (GMT) Advances in molecular and immunodiagnostics are enabling a personalized, high-precision approach to health in many clin...
    Speaker: Matthew Davies , Amy Webster , Mitch Gore , Renee Rathjen
    Sponsored By: Cytiva, IDT
    5
     
     
    SEP 14, 2021 | 7:00 AM
    What prevents you from increasing your PCR productivity?
    What prevents you from increasing your PCR productivity?
    Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...
    Speaker: Arora Phang, PhD
    Sponsored By: Eppendorf
    24 1
    MAY 25, 2021 | 8:00 AM
    Complete Workflow Solution from Gene-to-Protein
    Complete Workflow Solution from Gene-to-Protein
    Date: May 25, 2021 Time: 8:00am (PDT) Reliable expression of recombinant proteins in human, CHO, or insect cells is essential for many aspects of biomedical research and drug development, bu...
    Speaker: Stephan Fath, PhD
    Sponsored By: Thermo Fisher Scientific
    16 1
    MAY 11, 2021 | 10:00 AM
    Secure Your Next Great Discovery
    Secure Your Next Great Discovery
    Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
    Speaker: Paulina Kocjan , Kate Meola , Zareh Zurabyan
    Presented at: Eppendorf Planet of Knowledge - A New Dimension
    Sponsored By: Eppendorf
    8
    FEB 24, 2021 | 10:00 AM
    Biosafety Enclosures and the Automated Lab: Steps for Success
    Biosafety Enclosures and the Automated Lab: Steps for Success
    DATE: February 24, 2021 TIME: 10am PST Automated lab instruments such as liquid handlers and cell sorters are increasingly common in all types of laboratories, driving fast results for labor...
    Speaker: David Wasescha , Simon Fogarty
    Sponsored By: Labconco
    15
    DEC 02, 2020 | 8:00 AM
    Optimize your bioprocess - From shaker to bioreactor
    Optimize your bioprocess - From shaker to bioreactor
    DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
    Speaker: Ines Hartmann , David Solbach
    Sponsored By: Eppendorf
    11
    SEP 30, 2020 | 6:00 AM
    Enhancing efficiency and specificity with improved CRISPR components and a new CRISPR analysis pipeline
    Enhancing efficiency and specificity with improved CRISPR components...
    Genome editing with an expanded CRISPR-Cas tool set increases the opportunity to make intentional, targeted changes in the genome. Furthermore, improved specificity of genome editing and abi...
    Speaker: Ashley Jacobi
    Presented at: CRISPR Virtual Event Series 2020
    Sponsored By: IDT
    2
    JUL 22, 2020 | 10:00 AM
    Molecular Diagnostic Solutions in a Pandemic: Planning for the 2020/2021 Flu Season with the Implementation of the ePlex® Respiratory Pathogen Panel 2
    Molecular Diagnostic Solutions in a Pandemic: Planning for the...
    DATE: July 23, 2020 TIME: 10:00 am PDT The SARS-CoV-2 pandemic has taken a toll on many sectors of the medical community. As the pandemic took a grip on the laboratory, the need for diagnost...
    Speaker: Heba Mostafa, MD, PhD, D(ABMM)
    Sponsored By: GenMark Dx
    27 13
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    Oligo Synthesis
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    Virtual Events

    • NOV 10, 2020
      Solving the Unsolved in Mass Spec; Agilent Innovation and Collaboration For Today's Lab
      Solving the Unsolved in Mass Spec; Agilent Innovation and Collaboration...
      Please join us for this FREE workshop, as we present Agilent’s LC/MS hardware and software solutions for getting the most out of your analysis data....
      13
      MAY 10, 2017  | 6:00 AM PDT
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      Genetics and Genomics Virtual Event Series 2017
      The 5th Annual Event in the Genetics and Genomics Virtual Event Series is now On Demand. This event covers the most recent and exciting advances in genetics research....
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    NOV 10, 2020
    Solving the Unsolved in Mass Spec; Agilent Innovation and Collaboration For Today's Lab
    Solving the Unsolved in Mass Spec; Agilent Innovation and Collaboration...
    Please join us for this FREE workshop, as we present Agilent’s LC/MS hardware and software solutions for getting the most out of your analysis data....
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    MAY 10, 2017  | 6:00 AM PDT
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    Genetics and Genomics Virtual Event Series 2017
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