Oligo Synthesis
Oligo Synthesis: Oligonucleotide synthesis is the chemical synthesis of relatively short fragments of nucleic acids with defined chemical structure (sequence). The technique is extremely useful in current laboratory practice because it provides a rapid and inexpensive access to custom-made oligonucleotides of the desired sequence. Whereas enzymes synthesize DNA and RNA only in a 5' to 3' direction, chemical oligonucleotide synthesis does not have this limitation, although it is, most often, carried out in the opposite, 3' to 5' direction. Currently, the process is implemented as solid-phase synthesis using phosphoramidite method and phosphoramidite building blocks derived from protected 2'-deoxynucleosides (dA, dC, dG, and T), ribonucleosides (A, C, G, and U), or chemically modified nucleosides, e.g. LNA or BNA.
What's Popular in Oligo Synthesis
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OCT 30, 2018Drug Discovery & Development
OCT 30, 2018Understanding how cancer cells avoid death despite their DNA being damaged will create new strategies to enhance cancer ...WRITTEN BY: Nouran Amin
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JAN 23, 2020 9:00 AM PSTC.E. CREDITS
JAN 23, 2020 9:00 AM PSTDATE: January 23, 2020 TIME: 9:00am PST, 12:00pm EST...Speaker: Matthew Poling, PhDSponsored By: Thermo Fisher Scientific - InvitrogenSEP 05, 2019 4:00 PM CESTC.E. CREDITS
SEP 05, 2019 4:00 PM CESTDATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...Speaker: Tim Schommartz, PhDSponsored By: EppendorfFEB 27, 2019 10:30 AM PSTC.E. CREDITS
FEB 27, 2019 10:30 AM PSTAn aptamer (also known as a synthetic antibody) is a stable DNA, RNA, or peptide ligand that binds with high affinity and specificity to targets such as small molecules, peptides, proteins, b...Speaker: G. Thomas Caltagirone, PhDPresented at: Drug Discovery 2019MAR 31, 2016 8:00 AM PDT
MAR 31, 2016 8:00 AM PDTDATE: March 31, 2016 TIME: 8am PT, 11am ET, 4pm GMT In this webinar, you will learn: Basics of homology-directed repair (HDR) using CRISPR-Cas9 Selection of CRISP...
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MAY 10, 2017 6:00 AM PDTC.E. CREDITS
MAY 10, 2017 6:00 AM PDTThe 5th Annual Genetics and Genomics virtual conference is now On Demand. This event covers the most recent and exciting advances in genetics research. LabRoots invites research scientists, p...
