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    PTEN

    PTEN is a human gene coding for an enzyme called phosphatase and tensin homolog (PTEN). PTEN in a tumor suppressor gene which prevents mutations from occurring in genetic code. Therefore, mutations in PTEN are prevalent in many malignancies including brain, breast, lung, and prostate cancers.

    Webinars

    • JUN 21, 2022 | 6:00 AM
      The future of predictive genomics in Israel
      The future of predictive genomics in Israel
      Date: June 21, 2022 Time: 6:00am (PDT), 9:00am (EDT), 3:00pm (CEST) The global understanding and practice of medicine is currently undergoing a revolutionary change. This shift to precision...
      Speaker: Zisis Kozlakidis , David Hanna , Dr. Yehudit Cohen , Sowmiya Moorthie , Shai Carmi
      Sponsored By: Thermo Fisher Scientific
      27
      OCT 07, 2020 | 12:00 AM
      Immunotherapy in Prostate and Renal Cell Carcinoma: Panoply of Futuristic Therapies
      Immunotherapy in Prostate and Renal Cell Carcinoma: Panoply of...
      Immune therapy approaches are being used in many different solid cancers today including clear cell renal carcinoma (mccRCC) and metastatic prostate adenocarcinoma. Over the past few years i...
      Speaker: Benjamin Maughan, MD, PharmD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      4
      MAY 19, 2020 | 12:45 PM
      Assessing Immune Biomarkers of Response to Anthracyclines in Breast Cancer
      Assessing Immune Biomarkers of Response to Anthracyclines in Breast...
      Background: Pathologists have long recognized that the interaction between immune and tumour cells is critical in the development and progression of breast cancer. Studies have demonstrated...
      Speaker: Melanie Spears, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      APR 10, 2019 | 12:00 PM
      Transforming Oncology with ctDNA+ctRNA Liquid Biopsy Solutions
      Transforming Oncology with ctDNA+ctRNA Liquid Biopsy Solutions
      Determining which patients would derive clinical benefit from immunotherapy is a compelling clinical question. Biomarkers have been shown to predict therapy outcome in various types of cancer...
      Speaker: Shidong Jia, MD, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      4
      OCT 11, 2018 | 9:00 AM
      Destabilization and Degradation of MYC: More Ways Than One
      Destabilization and Degradation of MYC: More Ways Than One
      The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
      Speaker: Jason De Melo, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      MAR 15, 2018 | 9:00 AM
      Axon Regeneration in the CNS: Insights from the Optic Nerve
      Axon Regeneration in the CNS: Insights from the Optic Nerve
      The inability of neurons to regenerate damaged axons within the CNS has dire consequences for victims of traumatic or ischemic brain injury and multiple neurodegenerative diseases. Like other...
      Speaker: Larry Benowitz, PhD
      Presented at: Neuroscience Virtual Event Series 2018
      1
      OCT 12, 2017 | 10:30 AM
      Hypersecretion of fibroblast-derived exosomes during chemotherapy promotes pancreatic cancer chemoresistance
      Hypersecretion of fibroblast-derived exosomes during chemotherapy...
      Pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of only 9%. Acquired drug resistance is a major factor that limits the effectiveness of chemotherapy. Exosomes, secreted...
      Speaker: Reginald Hill, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
      1
      JAN 26, 2016 | 8:00 AM
      WEBINAR: Concordance of PTEN gene status in circulating tumor cells and tumor tissue from mCRPC patients
      WEBINAR: Concordance of PTEN gene status in circulating tumor...
      DATE: January 26th, 2016 TIME: 8am pacific, 11am eastern PTEN gene loss occurs frequently in castration-resistant prostate cancer (CRPC) and may drive progression through activation of th...
      Speaker: Edith Szafer-Glusman, PhD
      Sponsored By: Epic Sciences, Epic Sciences
      9
      MAY 14, 2015 | 1:30 PM
      Germline Cancer Genetics in 2015
      Germline Cancer Genetics in 2015
      Germline cancer genetics became a reality with the cloning of the tumor suppressor gene RB1 for hereditary retinoblastoma in 1986 by Friend and Weinberg. The existence of cancer susceptibili...
      Speaker: Judy E Garber, MD, MPH
      Presented at: Genetics and Genomics Virtual Event Series 2015
      4
      SEP 16, 2014 | 9:30 AM
      Analysis of Oncomine Knowledgebase to identify NFE2L2 pathway as a novel therapeutic opportunity in multiple cancer types
      Analysis of Oncomine Knowledgebase to identify NFE2L2 pathway...
      Late-stage drug attrition rates in oncology remain higher than in other therapeutic areas. To reduce attrition, it is critical to identify appropriate drug targets and pre-clinical models. Th...
      Speaker: Nickolay Khazanov, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
      18
      FEB 05, 2014 | 2:00 PM
      C.E. CREDITS
      The impact of genetic background in mouse and rat models: concerns and solutions
      The impact of genetic background in mouse and rat models: concerns...
      It is increasingly recognized that the genetic background (i.e., all genomic sequences other than the gene(s) of interest) can have profound influences on the phenotype of an animal model. I...
      Speaker: Fernando Benavides, DVM, PhD, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      21
    JUN 21, 2022 | 6:00 AM
    The future of predictive genomics in Israel
    The future of predictive genomics in Israel
    Date: June 21, 2022 Time: 6:00am (PDT), 9:00am (EDT), 3:00pm (CEST) The global understanding and practice of medicine is currently undergoing a revolutionary change. This shift to precision...
    Speaker: Zisis Kozlakidis , David Hanna , Dr. Yehudit Cohen , Sowmiya Moorthie , Shai Carmi
    Sponsored By: Thermo Fisher Scientific
    27
    OCT 07, 2020 | 12:00 AM
    Immunotherapy in Prostate and Renal Cell Carcinoma: Panoply of Futuristic Therapies
    Immunotherapy in Prostate and Renal Cell Carcinoma: Panoply of...
    Immune therapy approaches are being used in many different solid cancers today including clear cell renal carcinoma (mccRCC) and metastatic prostate adenocarcinoma. Over the past few years i...
    Speaker: Benjamin Maughan, MD, PharmD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    4
    MAY 19, 2020 | 12:45 PM
    Assessing Immune Biomarkers of Response to Anthracyclines in Breast Cancer
    Assessing Immune Biomarkers of Response to Anthracyclines in Breast...
    Background: Pathologists have long recognized that the interaction between immune and tumour cells is critical in the development and progression of breast cancer. Studies have demonstrated...
    Speaker: Melanie Spears, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
    APR 10, 2019 | 12:00 PM
    Transforming Oncology with ctDNA+ctRNA Liquid Biopsy Solutions
    Transforming Oncology with ctDNA+ctRNA Liquid Biopsy Solutions
    Determining which patients would derive clinical benefit from immunotherapy is a compelling clinical question. Biomarkers have been shown to predict therapy outcome in various types of cancer...
    Speaker: Shidong Jia, MD, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    4
    OCT 11, 2018 | 9:00 AM
    Destabilization and Degradation of MYC: More Ways Than One
    Destabilization and Degradation of MYC: More Ways Than One
    The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
    Speaker: Jason De Melo, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
     
     
  • MAR 15, 2018 | 9:00 AM
    Axon Regeneration in the CNS: Insights from the Optic Nerve
    Axon Regeneration in the CNS: Insights from the Optic Nerve
    The inability of neurons to regenerate damaged axons within the CNS has dire consequences for victims of traumatic or ischemic brain injury and multiple neurodegenerative diseases. Like other...
    Speaker: Larry Benowitz, PhD
    Presented at: Neuroscience Virtual Event Series 2018
    1
    OCT 12, 2017 | 10:30 AM
    Hypersecretion of fibroblast-derived exosomes during chemotherapy promotes pancreatic cancer chemoresistance
    Hypersecretion of fibroblast-derived exosomes during chemotherapy...
    Pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of only 9%. Acquired drug resistance is a major factor that limits the effectiveness of chemotherapy. Exosomes, secreted...
    Speaker: Reginald Hill, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
    1
    JAN 26, 2016 | 8:00 AM
    WEBINAR: Concordance of PTEN gene status in circulating tumor cells and tumor tissue from mCRPC patients
    WEBINAR: Concordance of PTEN gene status in circulating tumor...
    DATE: January 26th, 2016 TIME: 8am pacific, 11am eastern PTEN gene loss occurs frequently in castration-resistant prostate cancer (CRPC) and may drive progression through activation of th...
    Speaker: Edith Szafer-Glusman, PhD
    Sponsored By: Epic Sciences, Epic Sciences
    9
    MAY 14, 2015 | 1:30 PM
    Germline Cancer Genetics in 2015
    Germline Cancer Genetics in 2015
    Germline cancer genetics became a reality with the cloning of the tumor suppressor gene RB1 for hereditary retinoblastoma in 1986 by Friend and Weinberg. The existence of cancer susceptibili...
    Speaker: Judy E Garber, MD, MPH
    Presented at: Genetics and Genomics Virtual Event Series 2015
    4
    SEP 16, 2014 | 9:30 AM
    Analysis of Oncomine Knowledgebase to identify NFE2L2 pathway as a novel therapeutic opportunity in multiple cancer types
    Analysis of Oncomine Knowledgebase to identify NFE2L2 pathway...
    Late-stage drug attrition rates in oncology remain higher than in other therapeutic areas. To reduce attrition, it is critical to identify appropriate drug targets and pre-clinical models. Th...
    Speaker: Nickolay Khazanov, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
    18
     
     
  • FEB 05, 2014 | 2:00 PM
    C.E. CREDITS
    The impact of genetic background in mouse and rat models: concerns and solutions
    The impact of genetic background in mouse and rat models: concerns...
    It is increasingly recognized that the genetic background (i.e., all genomic sequences other than the gene(s) of interest) can have profound influences on the phenotype of an animal model. I...
    Speaker: Fernando Benavides, DVM, PhD, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    21
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