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    Tumor development

    Tumor development, or tumorigenesis, broadly describes the process by which normal cells gain malignant properties. Tumor development includes growth functions like cellular differentiation, proliferation, and metastasis.

    Webinars

    • SEP 16, 2020 | 12:15 PM
      High-resolution HCA-based phenotypic profiling of tumor spheroids and organoids
      High-resolution HCA-based phenotypic profiling of tumor spheroids...
      Image-based high-content screening (HCS) involving cancer cell lines grown in conventional two-dimensional (2D) cell culture, has provided a cornerstone assay for searching new agents to tre...
      Speaker: Meritxell B. Cutrona, PhD
      Presented at: 7th Annual Conference: SBI2 High Content
      2
      SEP 16, 2020 | 9:00 AM
      Deep multi-omic phenotyping of biospecimens for immuno-oncology applications
      Deep multi-omic phenotyping of biospecimens for immuno-oncology...
      Date: September 16, 2020 Time: 9:00am PTD, 12:00pm EDT Harnessing the power of the host immune system to treat diseases has been transformational in patient care. Physiologically relevant ce...
      Speaker: Dr. Shawn Fahl
      Sponsored By: Miltenyi Biotec
      11
      SEP 15, 2020 | 8:00 AM
      Next generation ultra high content analysis of the tumor immune microenvironment using MICS technology
      Next generation ultra high content analysis of the tumor immune...
      DATE: September 15, 2020 TIME: 08:00am PT Tumorigenesis and cancer progression are affected by the tumor immune microenvironment (TIME). The TIME not only influences the efficiency of existi...
      Speaker: Stefan Eulitz
      Sponsored By: Miltenyi Biotec
      15 2
      SEP 10, 2020 | 9:00 AM
      An Insider's Look: How One Parameter Can Optimize Key Phases of Bioprocessing Workflows
      An Insider's Look: How One Parameter Can Optimize Key Phases of...
      Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
      Speaker: Tara Barreira , Kristeena Wright
      Sponsored By: Advanced Instruments
      7
      SEP 10, 2020 | 7:30 AM
      Keynote Presentation: Discovery of a gene-microbiome interaction in lung cancer: lessons learned and future directions
      Keynote Presentation: Discovery of a gene-microbiome interaction...
      The selective pressure placed on the resident microbiota by local changes in the host environment – DNA damage, chronic inflammation, metabolic shifts, barrier damage, reduced immunosu...
      Speaker: K. Leigh Greathouse, PhD, MPH, MS, RD
      Presented at: Microbiology Week Virtual Event Series 2020
      3
      SEP 08, 2020 | 11:00 PM
      Recombination, lineage-specific mutations and the emergence of SARS-CoV-2
      Recombination, lineage-specific mutations and the emergence of...
      The recent outbreak of SARS-CoV-2 underscores the need for understanding the evolutionary processes that drive the emergence and adaptation of zoonotic viruses in humans. Here, we show that...
      Speaker: Ioan Filip, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 08, 2020 | 9:00 AM
      Advancing Toward Personalized Medicine in Lung Cancer: A Focus on Gene Rearrangement Testing
      Advancing Toward Personalized Medicine in Lung Cancer: A Focus...
      Advances in genomics and molecular biomarker testing have led to tremendous improvements, ushering in a new era of personalized medicine especially in the oncology practice. Many of these bi...
      Speaker: Yelina Noskina, PhD
      Sponsored By: Scientific Affairs, Molecular Diagnostics at Abbott
      27 3
      SEP 03, 2020 | 9:00 AM
      The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
      The Complexities of SV Analytical Ultracentrifugation: AAVs are...
      DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
      Speaker: Dr. Lake Paul
      Sponsored By: Beckman Coulter Life Sciences
      12
      AUG 26, 2020 | 8:00 AM
      Bio-Layer Interferometry as a strategic platform to validate covalent "proximity inducing" small molecules with synthetic tumor Immunotherapeutic applications
      Bio-Layer Interferometry as a strategic platform to validate covalent...
      DATE: August 26, 2020 TIME: 8:00 am PDT The host immune "recognition" of cancer forms the basis of modern tumor immmunotherapy, a highly targeted treatment option with the demonstr...
      Speaker: Anthony Rullo , Nilshad Salim, Ph.D.
      Sponsored By: Sartorius
      13
      AUG 25, 2020 | 8:00 AM
      How LV and AAV Transfection Platforms will Shape the Future of Gene Therapy Manufacturing
      How LV and AAV Transfection Platforms will Shape the Future of...
      DATE: August 25, 2020 TIME: 8:00am PDT, 10:00am CDT, 11:00am EDT Recombinant lentivirus (LV) and adeno-associated virus (AAV) are critical components of cell and gene therapies, which show g...
      Speaker: Leisha Kopp
      Sponsored By: Mirus
      18 2
      AUG 20, 2020 | 10:00 AM
      A Novel Method for the Isolation of Highly Pure Carcinoma Cell Populations from FFPE Tissue Improves Sensitivity for Detecting Somatic Mutations
      A Novel Method for the Isolation of Highly Pure Carcinoma Cell...
      DATE: August 20, 2020 TIME: 10:00am PT, 1:00pm ET Millions of formalin-fixed paraffin-embedded (FFPE) tissue specimens are archived annually. The enormous number of FFPE specimens available...
      Speaker: Carina Emery
      Sponsored By: Miltenyi Biotec
      21 1
      AUG 06, 2020 | 10:00 AM
      Part VII: From biochemical nanosensors to imaging to informatics to COVID-19 convalescent plasma - developing diagnostics and therapies for clinical medicine
      Part VII: From biochemical nanosensors to imaging to informatics...
      Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
      Speaker: Freddy Nguyen, MD, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 06, 2020 | 12:00 AM
      From biochemical nanosensors to imaging to informatics to COVID-19 convalescent plasma - developing diagnostics and therapies for clinical medicine
      From biochemical nanosensors to imaging to informatics to COVID-19...
      Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
      Speaker: Freddy Nguyen, MD, PhD
      Presented at: 2020 Beckman Symposium
      1
      JUL 29, 2020 | 5:00 PM
      Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through the Incorporation of Live Cellular Imaging
      Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through...
      Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
      Speaker: Brad Larson
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      2
      JUL 29, 2020 | 3:00 PM
      Advances and trends enabling the growth of immune-based cancer research and therapeutics
      Advances and trends enabling the growth of immune-based cancer...
      With the recent successes of immunotherapies, a fresh breeze of optimism in the fight against cancer has reinvigorated the industry. Perhaps the greatest legacy will be the realization of th...
      Speaker: David Ferrick, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      3
      JUL 29, 2020 | 2:00 PM
      Route of 41BB/41BBL costimulation determines effector function of B7-H3-CAR.CD28ζ T cells
      Route of 41BB/41BBL costimulation determines effector function...
      B7-H3 is actively being explored as an immunotherapy target for pediatric patients with solid tumors using monoclonal antibodies or T cells expressing chimeric antigen receptors (CARs). B7-H...
      Speaker: Christopher DeRenzo, MD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
      JUL 29, 2020 | 8:00 AM
      High-throughput DNA damage analyses identify synergistic drug combinations to treat malignant brain tumours
      High-throughput DNA damage analyses identify synergistic drug...
      Current methods to treat malignant brain tumors are highly intrusive, leading to poor quality of life with abysmal patient survival rates. Combined with radiation therapy, first/second-line...
      Speaker: Sachin Katyal, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
      JUL 29, 2020 | 12:00 AM
      Phenotypic and MoA Analysis of Anti-Metastatic Molecules using 3D Tumoroid Invasion Assays, Kinetic Ligand Binding, and Cellular Microscopy
      Phenotypic and MoA Analysis of Anti-Metastatic Molecules using...
      Metastasis is the main cause of death in cancer patients and one of the most complex biological processes in human diseases (Hanahan et al., 2011). The development of therapies designed to f...
      Speaker: Brad Larson
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
      JUL 29, 2020 | 12:00 AM
      Modeling anti-tumor function of human T cells
      Modeling anti-tumor function of human T cells
      Mouse models have been essential for establishing the role of the T cells in anti-tumor responses, but they have limited utility in translational studies for the testing of candidate therape...
      Speaker: Michael Overstreet, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
      JUL 16, 2020 | 10:00 AM
      Implications of Rapid IDH1/IDH2 Testing for Liquid and Solid Tumors
      Implications of Rapid IDH1/IDH2 Testing for Liquid and Solid Tumors
      DATE: July 16, 2020 TIME: 10:00 am PDT This seminar reviews clinical utility of adopting rapid IDH1/2 testing in both hematological and solid tumors and describes the adjusted workflow devel...
      Speaker: Sarah Herlihy
      Sponsored By: Abbott Molecular Diagnostic
      15
      JUL 07, 2020 | 11:00 AM
      Comprehensive landscape of the tumor microenvironment analyzed with CyTOF® technology
      Comprehensive landscape of the tumor microenvironment analyzed...
      Immune escape mechanisms such as the induction/recruitment of immunosuppressive cells and the increased expression of various immunosuppressive molecules including PD-1/PD-1 ligands are esse...
      Speaker: Hiroyoshi Nishikawa, MD, PhD
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      2
      JUL 07, 2020 | 7:30 AM
      Deciphering T cell heterogeneity in humans through analysis of antigen-specificity
      Deciphering T cell heterogeneity in humans through analysis of...
      In line with the role of T cells as critical mediators of the adaptive immune response, recombinational and junctional diversity of the T cell receptor makes each T cell almost entirely uniq...
      Speaker: Evan Newell, PhD
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      2
      JUL 07, 2020 | 6:30 AM
      Deep immunophenotyping of cancer microenvironments by Imaging Mass Cytometry™
      Deep immunophenotyping of cancer microenvironments by Imaging...
      Multiplex immunophenotyping technologies are indispensable for a deeper understanding of biological systems. Until recently, high-dimensional cellular analyses implied the loss of tissue con...
      Speaker: Noel de Miranda, PhD
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      1
      JUL 02, 2020 | 12:15 PM
      Microsatellite instability analysis for studying immunotherapy and Lynch syndrome-related cancers
      Microsatellite instability analysis for studying immunotherapy...
      Microsatellite instability (MSI) is a hypermutation phenotype that results from impaired DNA mismatch repair (MMR). The presence of high levels of MSI (MSI-H) is potentially predictive of Ly...
      Speaker: Charles Baudo, PhD
      Presented at: APJ Virtual Genetic Solutions Tour 2020
      1
    SEP 16, 2020 | 12:15 PM
    High-resolution HCA-based phenotypic profiling of tumor spheroids and organoids
    High-resolution HCA-based phenotypic profiling of tumor spheroids...
    Image-based high-content screening (HCS) involving cancer cell lines grown in conventional two-dimensional (2D) cell culture, has provided a cornerstone assay for searching new agents to tre...
    Speaker: Meritxell B. Cutrona, PhD
    Presented at: 7th Annual Conference: SBI2 High Content
    2
    SEP 16, 2020 | 9:00 AM
    Deep multi-omic phenotyping of biospecimens for immuno-oncology applications
    Deep multi-omic phenotyping of biospecimens for immuno-oncology...
    Date: September 16, 2020 Time: 9:00am PTD, 12:00pm EDT Harnessing the power of the host immune system to treat diseases has been transformational in patient care. Physiologically relevant ce...
    Speaker: Dr. Shawn Fahl
    Sponsored By: Miltenyi Biotec
    11
    SEP 15, 2020 | 8:00 AM
    Next generation ultra high content analysis of the tumor immune microenvironment using MICS technology
    Next generation ultra high content analysis of the tumor immune...
    DATE: September 15, 2020 TIME: 08:00am PT Tumorigenesis and cancer progression are affected by the tumor immune microenvironment (TIME). The TIME not only influences the efficiency of existi...
    Speaker: Stefan Eulitz
    Sponsored By: Miltenyi Biotec
    15 2
    SEP 10, 2020 | 9:00 AM
    An Insider's Look: How One Parameter Can Optimize Key Phases of Bioprocessing Workflows
    An Insider's Look: How One Parameter Can Optimize Key Phases of...
    Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
    Speaker: Tara Barreira , Kristeena Wright
    Sponsored By: Advanced Instruments
    7
    SEP 10, 2020 | 7:30 AM
    Keynote Presentation: Discovery of a gene-microbiome interaction in lung cancer: lessons learned and future directions
    Keynote Presentation: Discovery of a gene-microbiome interaction...
    The selective pressure placed on the resident microbiota by local changes in the host environment – DNA damage, chronic inflammation, metabolic shifts, barrier damage, reduced immunosu...
    Speaker: K. Leigh Greathouse, PhD, MPH, MS, RD
    Presented at: Microbiology Week Virtual Event Series 2020
    3
     
     
  • SEP 08, 2020 | 11:00 PM
    Recombination, lineage-specific mutations and the emergence of SARS-CoV-2
    Recombination, lineage-specific mutations and the emergence of...
    The recent outbreak of SARS-CoV-2 underscores the need for understanding the evolutionary processes that drive the emergence and adaptation of zoonotic viruses in humans. Here, we show that...
    Speaker: Ioan Filip, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 08, 2020 | 9:00 AM
    Advancing Toward Personalized Medicine in Lung Cancer: A Focus on Gene Rearrangement Testing
    Advancing Toward Personalized Medicine in Lung Cancer: A Focus...
    Advances in genomics and molecular biomarker testing have led to tremendous improvements, ushering in a new era of personalized medicine especially in the oncology practice. Many of these bi...
    Speaker: Yelina Noskina, PhD
    Sponsored By: Scientific Affairs, Molecular Diagnostics at Abbott
    27 3
    SEP 03, 2020 | 9:00 AM
    The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
    The Complexities of SV Analytical Ultracentrifugation: AAVs are...
    DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
    Speaker: Dr. Lake Paul
    Sponsored By: Beckman Coulter Life Sciences
    12
    AUG 26, 2020 | 8:00 AM
    Bio-Layer Interferometry as a strategic platform to validate covalent "proximity inducing" small molecules with synthetic tumor Immunotherapeutic applications
    Bio-Layer Interferometry as a strategic platform to validate covalent...
    DATE: August 26, 2020 TIME: 8:00 am PDT The host immune "recognition" of cancer forms the basis of modern tumor immmunotherapy, a highly targeted treatment option with the demonstr...
    Speaker: Anthony Rullo , Nilshad Salim, Ph.D.
    Sponsored By: Sartorius
    13
    AUG 25, 2020 | 8:00 AM
    How LV and AAV Transfection Platforms will Shape the Future of Gene Therapy Manufacturing
    How LV and AAV Transfection Platforms will Shape the Future of...
    DATE: August 25, 2020 TIME: 8:00am PDT, 10:00am CDT, 11:00am EDT Recombinant lentivirus (LV) and adeno-associated virus (AAV) are critical components of cell and gene therapies, which show g...
    Speaker: Leisha Kopp
    Sponsored By: Mirus
    18 2
     
     
  • AUG 20, 2020 | 10:00 AM
    A Novel Method for the Isolation of Highly Pure Carcinoma Cell Populations from FFPE Tissue Improves Sensitivity for Detecting Somatic Mutations
    A Novel Method for the Isolation of Highly Pure Carcinoma Cell...
    DATE: August 20, 2020 TIME: 10:00am PT, 1:00pm ET Millions of formalin-fixed paraffin-embedded (FFPE) tissue specimens are archived annually. The enormous number of FFPE specimens available...
    Speaker: Carina Emery
    Sponsored By: Miltenyi Biotec
    21 1
    AUG 06, 2020 | 10:00 AM
    Part VII: From biochemical nanosensors to imaging to informatics to COVID-19 convalescent plasma - developing diagnostics and therapies for clinical medicine
    Part VII: From biochemical nanosensors to imaging to informatics...
    Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
    Speaker: Freddy Nguyen, MD, PhD
    Presented at: 2020 Beckman Symposium
    1
    AUG 06, 2020 | 12:00 AM
    From biochemical nanosensors to imaging to informatics to COVID-19 convalescent plasma - developing diagnostics and therapies for clinical medicine
    From biochemical nanosensors to imaging to informatics to COVID-19...
    Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
    Speaker: Freddy Nguyen, MD, PhD
    Presented at: 2020 Beckman Symposium
    1
    JUL 29, 2020 | 5:00 PM
    Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through the Incorporation of Live Cellular Imaging
    Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through...
    Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
    Speaker: Brad Larson
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    2
    JUL 29, 2020 | 3:00 PM
    Advances and trends enabling the growth of immune-based cancer research and therapeutics
    Advances and trends enabling the growth of immune-based cancer...
    With the recent successes of immunotherapies, a fresh breeze of optimism in the fight against cancer has reinvigorated the industry. Perhaps the greatest legacy will be the realization of th...
    Speaker: David Ferrick, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    3
     
     
  • JUL 29, 2020 | 2:00 PM
    Route of 41BB/41BBL costimulation determines effector function of B7-H3-CAR.CD28ζ T cells
    Route of 41BB/41BBL costimulation determines effector function...
    B7-H3 is actively being explored as an immunotherapy target for pediatric patients with solid tumors using monoclonal antibodies or T cells expressing chimeric antigen receptors (CARs). B7-H...
    Speaker: Christopher DeRenzo, MD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
    JUL 29, 2020 | 8:00 AM
    High-throughput DNA damage analyses identify synergistic drug combinations to treat malignant brain tumours
    High-throughput DNA damage analyses identify synergistic drug...
    Current methods to treat malignant brain tumors are highly intrusive, leading to poor quality of life with abysmal patient survival rates. Combined with radiation therapy, first/second-line...
    Speaker: Sachin Katyal, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
    JUL 29, 2020 | 12:00 AM
    Phenotypic and MoA Analysis of Anti-Metastatic Molecules using 3D Tumoroid Invasion Assays, Kinetic Ligand Binding, and Cellular Microscopy
    Phenotypic and MoA Analysis of Anti-Metastatic Molecules using...
    Metastasis is the main cause of death in cancer patients and one of the most complex biological processes in human diseases (Hanahan et al., 2011). The development of therapies designed to f...
    Speaker: Brad Larson
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
    JUL 29, 2020 | 12:00 AM
    Modeling anti-tumor function of human T cells
    Modeling anti-tumor function of human T cells
    Mouse models have been essential for establishing the role of the T cells in anti-tumor responses, but they have limited utility in translational studies for the testing of candidate therape...
    Speaker: Michael Overstreet, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
    JUL 16, 2020 | 10:00 AM
    Implications of Rapid IDH1/IDH2 Testing for Liquid and Solid Tumors
    Implications of Rapid IDH1/IDH2 Testing for Liquid and Solid Tumors
    DATE: July 16, 2020 TIME: 10:00 am PDT This seminar reviews clinical utility of adopting rapid IDH1/2 testing in both hematological and solid tumors and describes the adjusted workflow devel...
    Speaker: Sarah Herlihy
    Sponsored By: Abbott Molecular Diagnostic
    15
     
     
  • JUL 07, 2020 | 11:00 AM
    Comprehensive landscape of the tumor microenvironment analyzed with CyTOF® technology
    Comprehensive landscape of the tumor microenvironment analyzed...
    Immune escape mechanisms such as the induction/recruitment of immunosuppressive cells and the increased expression of various immunosuppressive molecules including PD-1/PD-1 ligands are esse...
    Speaker: Hiroyoshi Nishikawa, MD, PhD
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
    2
    JUL 07, 2020 | 7:30 AM
    Deciphering T cell heterogeneity in humans through analysis of antigen-specificity
    Deciphering T cell heterogeneity in humans through analysis of...
    In line with the role of T cells as critical mediators of the adaptive immune response, recombinational and junctional diversity of the T cell receptor makes each T cell almost entirely uniq...
    Speaker: Evan Newell, PhD
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
    2
    JUL 07, 2020 | 6:30 AM
    Deep immunophenotyping of cancer microenvironments by Imaging Mass Cytometry™
    Deep immunophenotyping of cancer microenvironments by Imaging...
    Multiplex immunophenotyping technologies are indispensable for a deeper understanding of biological systems. Until recently, high-dimensional cellular analyses implied the loss of tissue con...
    Speaker: Noel de Miranda, PhD
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
    1
    JUL 02, 2020 | 12:15 PM
    Microsatellite instability analysis for studying immunotherapy and Lynch syndrome-related cancers
    Microsatellite instability analysis for studying immunotherapy...
    Microsatellite instability (MSI) is a hypermutation phenotype that results from impaired DNA mismatch repair (MMR). The presence of high levels of MSI (MSI-H) is potentially predictive of Ly...
    Speaker: Charles Baudo, PhD
    Presented at: APJ Virtual Genetic Solutions Tour 2020
    1
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