FEB 12, 2026 12:05 PM PST

Cannabis Access Tied to Big Drop in Daily Opioid Use

How can cannabis legalization influence opioid use? This is what a recent study published in Drug and Alcohol Dependence hopes to address as a team of researchers investigated behavior connections between cannabis use and opioid use. This study has the potential to help scientists, medical professionals, legislators, and the public better understand the benefits of cannabis, including how it can help the opioid epidemic.

For the study, the researchers analyzed survey data collected from 28,069 individuals designated as people who inject drugs (PWID) during 2012, 2015, 2018, and 2022 across 13 states. The goal of the study was to compare medical cannabis and medical plus recreational cannabis use to opioid use. The respondents were asked to report their past 30-day use for both cannabis and opioids. In the end, the researchers found that users who subscribed to both medical plus recreational cannabis use compared to just medical cannabis use experienced a 9-11 percent decline in opioid use.

The study notes in its conclusions, “Cannabis legalization may shape daily opioid consumption among PWID, potentially reducing drug-related harms. Differences in cannabis use following legalization may reflect disparate impact by race, due to structural racism or other factors. Future research examining whether policy attributable changes in substance use manifest health benefits among PWID is critical to developing evidence- based cannabis reform.”

This study comes as the opioid crisis remains a high talking point among medical and public circles in the United States. However, this also coincides with the rapid legalization of both medical and recreational cannabis across the country, as well. Therefore, studies like this demonstrate potential benefits of cannabis use resulting in a steady decline of opioid use.

What new insight into cannabis and opioids will researchers make in the coming years and decades? Only time will tell, and this is why we science!

As always, keep doing science & keep looking up!

Sources: Drug and Alcohol Dependence, NORML

About the Author
Master's (MA/MS/Other)
Laurence Tognetti is a six-year USAF Veteran who earned both a BSc and MSc from the School of Earth and Space Exploration at Arizona State University. Laurence is extremely passionate about outer space and science communication, and is the author of "Outer Solar System Moons: Your Personal 3D Journey".
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